As a Histotech Assistant working in the Histology Laboratory, you will be responsible for contributing to diagnosis, treatment, and care of patients by performing a volume and variety of Histopathology technical procedures as trained under direct supervision including embedding of tissue blocks and performing microtomy.
Additional responsibilities include:
- Retrieval and verification of patient samples
- Tracking specimens
- Accessioning
- Specimen photography
- Processing tissue specimens using various protocols
- Maintaining laboratory equipment
- Performing Hematoxylin and Eosin staining
- Performing coverslipping techniques
- Performing case assembly and distribution
- Handling outside/consultation material
- Troubleshooting equipment, reagent, and case issues
- Reagent preparation
- Reviewing pending list/logs
- Filing and retrieving tissue blocks and slides
- Handling/disposal of hazardous chemicals
- Subject matter expert of Lab Information System
- Record retention
- Answering phones
Visit the Clinical Labs career site to watch a brief video of Olyvia discussing her role as a Histotech Assistant at Mayo Clinic.
*This position does not typically meet ASCP Board of Certification Route 2 eligibility requirements for Histology Technician Examination.
*Individuals hired to this position are required to complete 2 years in this position before becoming eligible to apply to other positions within Mayo Clinic.
**This position is not eligible for visa sponsorship; Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
QualificationsTo be considered for this position, you must have an associate's degree. In lieu of an associate degree, you may be considered if you have a high school diploma or GED and 2 years of relevant/demonstrated experience.
*This is a limited tenure position for a maximum of 3 years. You will be eligible to reduce to 0.5 full-time equivalency (FTE) if accepted into the Mayo Clinic School of Health Sciences (MCSHS) Histology Technician Program. You must work towards completion of MCSHS Histology Technician program prerequisites: https://college.mayo.edu/academics/health-sciences-education/histology-technician-program-arizona-florida-and-minnesota/.
Additional Requirements
- Medical terminology preferred.
- Laboratory or leadership experience preferred.
- Demonstrated communication, organizational, and problem-solving skills.
Application Requirements
*All must be included for your application to be considered:
- CV/Resume
- Cover letter
- NACES detailed international equivalency for foreign degrees.
- Internal candidates must provide their past three performance appraisals.
**DLMP employees that have been in current lab/position for less than 2 years must attach early release approval from supervisor.
***Non-DLMP internal applicants that have been in their current department/position for less than 1 year must attach early release approval from supervisor.
*International transcript:
- MUST have a DETAILED equivalency evaluation.
- MUST show US equivalent degree.
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Associate's degree OR high school diploma/GED plus 2 years relevant experience
- CV/Resume
- Cover letter
- NACES detailed international equivalency for foreign degrees
- Detailed international transcript equivalency showing US equivalent degree (if applicable)
- Demonstrated communication, organizational, and problem-solving skills
- Authorization to work in the U.S. without visa sponsorship (no sponsorship provided)
- Medical terminology knowledge
- Laboratory or leadership experience
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.






