Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity.
The Importance of the Role
This internship represents an exceptional opportunity for a student interested in biotech R&D to gain hands on experience with advanced automation technologies, including Tecan Fluent liquid handling systems, automated tangential flow filtration platforms, and high throughput purification modalities.
The intern will work in a highly collaborative, cross functional environment, and will contribute to activities that directly impact Sarepta’s ability to generate critical research materials (Fabs, mAbs, proteins, and other biologics) for internal chemistry and biology partners. They will also play a key role in process development efforts for early-stage research programs. This role offers scientific mentorship, including support from team members experienced in academic and industry training.
The Opportunity to Make a Difference
In this role, the intern will have the opportunity to:
Develop, test, and optimize workflows for the Autopulse automated tangential flow filtration instrument, enabling efficient buffer exchange and concentration of multiple therapeutic modalities (Fab, Mab, proteins, and oligo conjugates).
Perform experimental design, execution, and data analysis to establish high-quality TFF workflows following ERPD pipeline updates.
Support downstream process development efforts using Tecan Fluent systems in both RoboColumn and batch filter plate formats to generate critical purification data for upstream and downstream development teams.
Set up, execute, and troubleshoot high throughput purification experiments to accelerate development timelines across ERPD.
Collaborate closely with upstream, downstream, and analytical development groups, gaining exposure to multiple scientific disciplines and technologies.
Document experimental execution and results to enhance team knowledge sharing and process reliability.
Contribute to continuous improvement initiatives by identifying opportunities to improve workflow efficiency, automation robustness, and interteam collaboration.
More about You
Current undergraduate or graduate student in Chemical Engineering, Bioengineering, Biochemistry, Biotechnology, Biology, or related scientific discipline.
Strong interest in laboratory research, bioprocess development, or automation enabled experimentation.
Comfort working with complex instrumentation and a willingness to learn new automated systems and workflows.
Strong analytical, problem-solving, and documentation skills.
Ability to thrive in a collaborative team environment and communicate effectively with peers and mentors.
Demonstrated curiosity, attention to detail, and motivation to improve laboratory processes.
Preferred Qualifications
Prior hands on experience with laboratory automation, liquid handlers (e.g., Tecan), or filtration systems is a plus.
Experience working with proteins, antibodies, or viral vectors in an academic or industry setting.
Familiarity with chromatography, filtration, or other downstream purification techniques.
Program Timeline
This application is for a 12-week summer internship program that will start on May 18th and conclude on August 7th, 2026.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
Top Skills
What We Do
Sarepta Therapeutics, headquartered in Cambridge, Massachusetts, is a global biotechnology company on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development. Our vast pipeline is driven by our multi-platform Precision Genetic Medicine Engine in gene therapy, RNA and gene editing.
For information on our Community Guidelines, please visit sarepta.com/community-guidelines.
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