Head of Operations

Sorry, this job was removed at 08:21 p.m. (UTC) on Tuesday, Sep 22, 2026
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Boston, MA, USA
In-Office
175K-200K Annually
Senior level
Artificial Intelligence • Healthtech • Software • Biotech
The Role
Lead operations and people functions for a rapidly scaling global startup. Own culture, performance management, manager development, HRIS, payroll, benefits, onboarding, compliance, compensation, leveling, recruiting strategy, headcount planning, interview processes, and employer branding across US and European entities. Build scalable systems and processes while partnering closely with company leadership in a hands-on role.
Summary Generated by Built In

Job Title: Head of Operations
Employment Status: Full-time
Office Hours: Monday - Friday; 4:1 hybrid schedule
Location: Boston, Massachusetts
Compensation: $175,000-200,000 base + variable + equity options
*compensation may be negotiated based on experience level

About Ketryx:

Ketryx is an AI platform that enables healthcare and life sciences companies to ship life-saving products in weeks instead of years.

Exploding product complexity is burying companies in compliance paperwork and blocking innovation. Our AI software removes this friction, dissolving the historical tradeoff between innovation and compliance, and enables regulated industries to innovate at the pace of modern software.

Ketryx already touches the lives of millions of patients and powers 4 of the world’s top 5 life science companies and 25% of the Fortune 500 life science market. Backed by Lightspeed Ventures, our founders are the former Head of AI at Amgen and CTO of Wolfram Cloud.

Healthcare and life sciences is just the beginning for us. Automotive, aerospace, energy — if it’s regulated, it’s because society decided it matters. These products move humanity, shape our future, and are safety-critical. Come join us and help build the AI platform to power safe innovation.

The Role

We're hiring a Head of Operations to own all things operations & people as Ketryx scales. You'll inherit a small, capable team and a company that is growing quickly across the US and Europe, with all the ambiguity and opportunity that comes with it. Your mandate is over the people here at Ketryx & how we work, by building + refining our systems, hiring engine, and culture that allow us to grow fast and execute without losing what makes our team effective.

This is a hands-on leadership role based in Boston, including quarterly travel to our Vienna office. You'll set our strategy around cross-functional collaboration, be responsible for designing how we work, and answer a tactical People question in Slack. Our customers build products that keep people alive. The faster we help them ship safely, the sooner these products reach patients. How well we hire, develop, and support our own team is critical!

You will report to Erez, our CEO and Co-founder

Responsibilities

Culture and Collaboration

  • Ensure our values are incorporated into how we work every day at Ketryx, focusing on creating an environment where people can execute on a world-class level
  • Own performance management: goal setting, review cycles, calibration, and the harder conversations that follow
  • Build manager capability across a team where many leaders are first-time managers
  • Run engagement measurement and, more importantly, act on what it tells us

People Operations & Compensation

  • Own HRIS, payroll, benefits, onboarding, and offboarding across US and European entities
  • Build process where it removes friction and resist it where it doesn't
  • Build out a leveling framework, compensation bands, and equity philosophy that hold up across engineering, GTM, and G&A
  • Maintain employment compliance across multiple countries and states as we expand
  • Run market benchmarking and annual comp cycles in partnership with Finance

Talent acquisition and scaling

  • Build a hiring engine that consistently lands senior engineers, GTM talent, and life sciences domain experts in a competitive market
  • Partner with leadership on headcount planning and sequencing — what we hire, when, and why
  • Raise the bar on interview design, structured evaluation, and candidate experience so hiring decisions are consistent and defensible
  • Develop Ketryx's employer brand to help us attract high-caliber talent
Required Skills
  • 8+ years in HR/People Operations with at least three leading the function or a major pillar of it, especially at high growth startups
  • Strong opinions on what can work, a willingness to try something new, and a network of People leaders to tap into for broader questions
  • Direct experience scaling a company through significant headcount growth — you've seen what breaks at 100, 200, 500 people and have opinions about it
  • Comfort operating without a large team or established playbook — you build the thing and then run it
  • Strong recruiting instincts; you can assess engineering and GTM talent markets and partner credibly with engineering leaders
  • Demonstrated ownership of compensation and leveling design
  • Multi-country employment experience (US and EU) or clear evidence you can get up to speed fast
  • Sound judgment in ambiguous, confidential situations, and the directness to bring hard news to the leadership team early
Preferred Skills
  • Experience supporting distributed teams across US and European time zones
What We Offer
  • Competitive compensation
  • Generous stock options possible
  • Work in an exciting field with a positive impact on the world
  • Opportunity to learn and grow as part of a global team
  • Generous PTO for full-time

Ketryx is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, color, family or medical care leave, gender identity or expression, genetic information, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran status, race, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable laws, regulations and ordinances

Ketryx is saving and improving lives by making medical software safe and reliable. We empower software teams building medical applications to create safe, secure, and compliant products used by patients and providers worldwide. We believe that, by automating much of the documentation and quality processes, teams will be able to produce safer and more innovative medical software faster.

Ketryx is at the forefront of helping teams incorporate AI/ML into medical software and that’s why we need you!

What We Offer
  • Competitive compensation
  • Generous stock options possible
  • Work in an exciting field with a positive impact on the world
  • Opportunity to learn and grow as part of a global team
  • Generous PTO for full-time

Ketryx is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, color, family or medical care leave, gender identity or expression, genetic information, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran status, race, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable laws, regulations and ordinances

Ketryx is saving and improving lives by making medical software safe and reliable. We empower software teams building medical applications to create safe, secure, and compliant products used by patients and providers worldwide. We believe that, by automating much of the documentation and quality processes, teams will be able to produce safer and more innovative medical software faster.

Ketryx is at the forefront of helping teams incorporate AI/ML into medical software and that’s why we need you!


Skills Required

  • 8+ years of experience in HR or People Operations
  • At least 3 years leading the HR/People function or a major pillar of it
  • Experience working at high-growth startups
  • Experience scaling a company through significant headcount growth
  • Ability to operate without a large team or established playbook
  • Strong recruiting instincts and ability to assess engineering and go-to-market talent markets
  • Experience owning compensation and leveling design
  • Multi-country employment experience across the US and Europe, or ability to quickly develop it
  • Sound judgment in ambiguous and confidential situations
  • Direct communication skills, including bringing difficult news to leadership early
  • Experience supporting distributed teams across US and European time zones

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The Company
HQ: Cambridge, MA
70 Employees
Year Founded: 2021

What We Do

Ketryx is the first and only connected application lifecycle management software for the life sciences industry. Our automation-based software enables companies building FDA-regulated software and AI-based applications to accelerate development through modern cloud-based tools while improving quality and compliance. Ketryx creates a real-time, and traceable, single source of truth by overlaying product development tools and connecting all items, risks, code, and tests. Teams reduce their time to market with automated documentation and improve their quality and compliance through the enforcement of SOPs across connected systems

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