Global Payroll Manager

Hippocratic AI has developed the only safe, safety-focused Large Language Model (LLM) for healthcare, resulting in the only autonomous patient-facing clinical agents in the industry. We are delivering abundance for the first time in healthcare by bringing deep clinical expertise to every human. No other technology has the potential to have this level of global impact on health. Come join the most capitalized healthcare AI company with the most deployed customers and the broadest platform of applications. Our highly mission-oriented team, coupled with innovative partners like the Cleveland Clinic, Baylor Scott & White, Northwestern, Wellspan, HCA, and Oschner, is building the most transformative company in healthcare in history.

• Reinvent healthcare with AI that puts safety first. We’re building the world’s first healthcare-only, safety-focused LLM — a breakthrough platform designed to transform patient outcomes at a global scale. This is category creation.

• Work with the people shaping the future. Hippocratic AI was co-founded by CEO Munjal Shah and a team of physicians, hospital leaders, AI pioneers, and researchers from institutions like El Camino Health, Johns Hopkins, Washington University in St. Louis, Stanford, Google, Meta, Microsoft, and NVIDIA.

• Backed by the world’s leading healthcare and AI investors. We recently raised a $126M Series C at a $3.5B valuation, led by Avenir Growth, bringing total funding to $404M with participation from CapitalG, General Catalyst, a16z, Kleiner Perkins, Premji Invest, UHS, Cincinnati Children’s, WellSpan Health, John Doerr, Rick Klausner, and others.

• Build alongside the best in healthcare and AI. Join experts who’ve spent their careers improving care, advancing science, and building world-changing technologies — ensuring our platform is powerful, trusted, and truly transformative

As the Global Payroll Manager, you will hold end-to-end ownership for the company’s payroll operations, optimizing processes to strategically support Hippocratic AI’s next phase of growth. This role requires extensive cross-functional collaboration with HR, Accounting, and Legal to ensure timely, accurate, and compliant payruns and regulatory filings across all jurisdictions. Over the long term, you will be responsible for building and leading a high-performance payroll operations team to scale with the global business.

Payroll Processing & Compliance:

• Own end-to-end payroll process for exempt and hourly employees across all global entities.

• Own payroll setup for new hires and ensure all employee changes (comp, deductions, benefits, garnishments, tax elections, etc.) are processed accurately and on time.

• Partner with the India Accounting team to ensure accurate and timely payroll administration for India-based employees, including support on local compliance requirements.

• Manage payroll administration through Employer of Record (EOR) providers across global jurisdictions and support payroll readiness for expansion into new countries/states.

• Ensure compliance with all applicable wage and hour regulations, payroll tax registration and filing requirements across relevant U.S. jurisdictions, and maintain complete payroll records aligned with legal and tax obligations.

• Develop, implement, and maintain robust payroll, time-off, leave, and workers’ compensation procedures and guidelines; monitor compliance and ensure operational accuracy.

• Drive payroll controls and documentation; serve as the payroll compliance owner (including SOX-ready controls, where applicable).

Audits, Reporting & Controls

• Perform pre- and post-payroll audits, prepare reconciliations, and conduct payroll variance analysis each cycle to proactively identify and resolve discrepancies.

• Own monthly/quarterly/annual payroll reconciliations and reporting, including:

  • W-2 and 1099 preparation

  • Quarterly/annual amendments

  • 401(k) testing and reconciliations

  • Payroll tax filings and reporting

• Manage incentive and equity payroll processing (ISOs, NQSOs), ensuring accurate withholding, reporting, and tax-related submissions, including estimated tax obligations when applicable.

• Liaise with auditors and coordinate payroll tax, benefits, and compliance audits; ensure documentation readiness and issue resolution.

Financial Reporting & Close

• Partner with Accounting to support month-end close processes, including creating and maintaining payroll and benefits journal entries, accruals, and reconciliation of payroll registers to the general ledger in accordance with GAAP.

• Prepare post-payroll reports and reconcile bank deposits and payroll funding, identifying discrepancies and resolving issues in a timely manner.

• Provide leadership with reporting and insights related to payroll forecasting, cash needs, and benefits requirements.

Process Improvement & Cross-Functional Partnership

• Collaborate closely with People, Finance, Legal, and internal stakeholders to ensure a seamless employee experience, resolve payroll issues quickly, and maintain data integrity across systems.

• Continuously improve payroll operations in a fast-paced environment by building scalable workflows, documenting processes, and strengthening internal controls to support future audits and growth.

Must Have:

• Bachelor’s degree (or equivalent practical experience) with 10+ years of progressive payroll experience, including ownership of U.S. payroll in a high-growth technology company; global payroll exposure strongly preferred.

• Deep knowledge of U.S. payroll, wage and hour compliance, and employment tax regulations, including federal and multi-state requirements (registrations, filings, and remittances).

• Experience operating in complex multi-state and multi-country environments, including managing payroll through Employer of Record (EOR) partners and supporting expansion into new jurisdictions.

• Working knowledge of payroll accounting principles, including journal entries, accruals, and payroll-to-GL reconciliations; close partnership with Accounting required (GAAP familiarity preferred).

• Experience administering equity and incentive payroll (RSUs, ISOs, NQSOs) and related payroll tax reporting and withholding.

• Hands-on experience with modern payroll and HRIS systems such as Rippling (preferred), ADP, Workday, or similar; ability to troubleshoot and improve workflows across integrated systems.

• Demonstrated ability to operate with high ownership in a fast-paced environment — able to prioritize competing deliverables, manage deadlines, and drive issues to resolution.

• Strong communication and stakeholder management skills, with the ability to partner effectively across People, Finance, Legal, external vendors, and employees.

• Excellent analytical and problem-solving capabilities, sound judgment, and exceptional attention to detail and accuracy.

Join us and help build the future of safe, life-changing AI in healthcare. There’s never been a more exciting moment to make an impact.

***Be aware of recruitment scams impersonating Hippocratic AI. All recruiting communication will come from @hippocraticai.com email addresses. We will never request payment or sensitive personal information during the hiring process.