Astera is a private foundation on a mission to steer science and technology toward an abundant future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to dramatically accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive scientific progress.
Unlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. You can read more about our mission, vision, and programming here.
Position SummaryWe are looking for a mission- and culturally-aligned finance leader to cover our Controller's planned leave of absence and own Astera's finance function end-to-end during that period. This is a contract role with a defined term. Depending on our needs and how the engagement goes, this role has the potential to convert to a permanent role owning FP&A and finance operations.
The engagement runs from September 2026 through June 2027. We intend to start ahead of the leave to allow for a substantial overlap and handoff with the Controller, so you'll build deep context before taking the reins. During the coverage period, you'll own accounting, treasury, compliance, and FP&A, with one direct report (an Accounting Manager).
Astera has doubled to 100 FTEs since December 2025 and projects growth to 300 by the end of 2027. As we scale, we anticipate a permanent, expanded finance leadership need. If the fit is right on both sides, this role is well-positioned to convert into full ownership of FP&A and finance operations—partnering with investment, operations, and programs leadership to manage the end-to-end budgets and grants behind our 30 internal projects (ranging from $1M to $20M each) and our external grantees.
This is ideal for a finance leader who thrives in dynamic, entrepreneurial environments, is comfortable stepping into full ownership quickly, and is energized by the possibility of helping build the financial foundation of a high-impact, experimental organization for the long run.
This role reports to the COO of the Foundation Division.
Key ResponsibilitiesDuring the coverage period, you'll own Finance end-to-end:
Lead FP&A: Partner with budget leads and Astera leadership on financial analysis, including budget-to-actuals reporting and deep-dive analyses.
Drive Financial Operations: Manage agreements and payments across vendors, payroll, grants, and investments. Work directly in Ramp, our spend management platform, to ensure data accuracy. Establish and revise program budgets and grants.
Lead Financial Reporting and Compliance: Oversee the preparation of accurate, timely financial statements and ensure successful completion of taxes and annual audits by managing relationships with accounting, audit, and tax partners.
Oversee the Balance Sheet and Treasury: Collaborate with internal and external partners to monitor and report on Astera's investment portfolio, supporting informed decision-making and risk management.
Should the role convert, the long-term focus shifts to permanent ownership of FP&A and finance operations, scaling our financial systems as Astera grows.
We're also looking for someone who will:
Continuously improve systems: The landscape is changing rapidly, and this role should be excited to strive for best-in-class financial systems that improve the team's efficiency and effectiveness.
Teach and learn from others: We care about professional development, and we're looking for someone excited to uplevel the full finance team.
Flex to "unknown unknowns": Astera is a new kind of philanthropic organization that doesn't constrain itself in how it delivers impact. This role will need to flex to emerging needs across the finance and operations stack.
~8–12 years of experience in financial management and strategic finance, preferably in startups. An ideal candidate has likely led the finance and accounting functions in a prior environment.
Motivated by enabling science that could reshape the future.
Exceptional relationship orientation and verbal + written communication.
Gives and receives feedback well.
Comfortable operating outside a fixed job description and thriving in a startup-like environment.
Eagerness to use AI and new technology as an opportunity to improve effectiveness.
Bias to action and experimentation.
Commitment to high standards, ownership, and tenacious problem solving.
This role is based at our Emeryville, CA office 5 days per week.
Skills Required
- 8-12 years of experience in financial management and strategic finance
- Experience leading finance and accounting functions
- Demonstrated FP&A and financial analysis experience (budget-to-actuals, deep-dive analyses)
- Accounting, treasury, and financial operations ownership (including payroll, payments, grants, investments)
- Experience working with Ramp or similar spend-management platforms
- Experience managing audits, tax filings, and relationships with accounting/audit/tax partners
- Experience managing grants and program budgets
- Exceptional verbal and written communication and stakeholder management
- Comfort operating in startup-like, fast-changing environments
- Eagerness to use AI and new technology to improve finance effectiveness
- Ability to work onsite in Emeryville, CA five days per week
What We Do
Astera is a private foundation with a $2.5B endowment focused on steering science and technology toward an abundant future for all. They operate like a high-velocity startup, integrating neuroscience, AI, and bioengineering for AGI research.
