Expert In Vitro Biologist

Posted 12 Days Ago
Be an Early Applicant
New York, NY, USA
In-Office
Mid level
Biotech • Pharmaceutical
The Role
Develop and optimize patient-derived and tissue-specific organoid and complex co-culture models for discovery oncology. Design and run semi-/high-throughput endpoint and kinetic assays using advanced microscopy. Perform 3D cell culture assays and molecular techniques (CellTiter-Glo, Western blot, ELISA, flow cytometry, IF/IHC) to assess viability, proliferation, differentiation, and drug responses.
Summary Generated by Built In

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence.  We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.  This position may include relocation benefits as well.  We aim to recruit the best people who stand out among their peers and embody our Core Values:

  • Client Focused: We only succeed when our clients succeed.
  • Outstanding: We deliver meticulous results through outstanding performance.
  • Good: We act ethically and morally.
  • Employee-Centric: We honor and support our employees.
  • Nimble: We are prepared to adapt in an ever-changing industry.
  • Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for an Expert In Vitro Biologist.

Job duties include, but are not limited to, the following:

  • Establish, expand, and maintain patient-derived and tissue-specific organoid cultures. Independently optimize protocols for improved fidelity, maturation, and biological relevance.
  • Independently develop, troubleshoot, and improve complex co-culture model systems incorporating primary human tumor cells, fibroblasts, immune cells, and microenvironment components to deliver robust scientific answers.
  • Establish and optimize novel in vitro assays using 3D organotypic models, complex co-cultures, organoids, transwell systems, air-liquid interface, and/or organ-on-a-chip platforms representing both healthy and disease states to support discovery oncology programs.
  • Design and execute semi- or high-throughput endpoint and kinetic assays for safety and efficacy screening of molecules during early discovery using advanced microscopy.
  • Perform 3D cell culture assays, including viability, proliferation, differentiation, and drug response studies, using cellular and molecular biology techniques such as CellTiter-Glo, Western blotting, ELISA, flow cytometry, and immunofluorescence staining.

Job requirements include, but are not limited to:

  • PhD in cell biology, bioengineering, cancer biology, or a related discipline; or MS in a related field with 4+ years of relevant research experience.
  • Working knowledge of at least one of the focus areas: renal, pancreatic, lung, or colon biology.
  • Experience with molecular biology techniques such as IF, IHC, western blotting, and flow cytometry.
  • Experience with advanced microscopy techniques (confocal, light sheet, high-content imaging) for assessing the phenotype of complex models and kinetic assays.
  • Excellent communication skills – verbal and written.
  • Works well both as a team and as an individual.
  • Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

This is a day shift position (approx. 8a-5p local time).

Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.

Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.

This job posting will remain open until 9/14/2026 or until a qualified candidate has been selected, whichever comes first.

Skills Required

  • PhD in cell biology, bioengineering, cancer biology, or related discipline; or MS with 4+ years relevant research experience
  • Experience establishing and maintaining patient-derived and tissue-specific organoid cultures
  • Experience developing and optimizing complex co-culture model systems incorporating primary human tumor cells, fibroblasts, immune cells, and microenvironment components
  • Working knowledge of at least one focus area: renal, pancreatic, lung, or colon biology
  • Experience with molecular biology techniques: immunofluorescence (IF), immunohistochemistry (IHC), Western blotting, and flow cytometry
  • Experience with advanced microscopy techniques: confocal, light sheet, and high-content imaging
  • Experience designing and executing semi- or high-throughput endpoint and kinetic assays using advanced microscopy
  • Experience with assay readouts such as CellTiter-Glo, ELISA, and other cellular/molecular endpoints
  • Excellent verbal and written communication skills
  • Strong teamwork, attention to detail, problem-solving, learning agility, and ability to work across functions
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The Company
HQ: Indianapolis, Indiana
71 Employees
Year Founded: 2005

What We Do

The pharmaceutical and biotech industries experienced a tremendous amount of change this past decade. For companies to remain relevant and competitive, they must respond quickly and effectively to the unique challenges they face. Our company was started to assist companies in navigating these hurdles. Cogent has earned a reputation for reliability regarding our partnership to our clients. We believe that the key to maintaining that commitment is attracting and retaining good people to be part of our team. Our commitment to our clients is intertwined with our commitment to our employees. Cogent employs talented individuals who also bring a positive, team oriented approach to the tasks at hand. Each day, our people demonstrate their motivation and initiative to make things simple and to innovate while being empowered by the drive to make the right decisions. This passion for excellence means our customers trust our partnership and employees choose to join – and stay with – Cogent Scientific.

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