Executive Director, IT Lead, Europe

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are seeking an experienced Regional IT Lead to establish and oversee the set up and execution of IT operations in Europe. This role will serve as the primary technology partner for business functions in Europe, also acting as the bridge between local stakeholders and global IT teams. The Regional IT Lead will ensure that IT needs are met in alignment with global platforms, delivering end-to-end solutions for local implementation while driving operational excellence in IT services. This leader will build and scale the regional IT function through a balanced model of internal team development and strategic vendor partnerships to deliver agile, high-quality support across the region.

Reporting directly to the SVP and General Manager, Europe Region, this individual will collaborate closely with country and regional leaders as well as global Information Sciences (IT) partners. The role also dotted-line reports to the VP, Commercial & Medical Affairs Information Systems. The position requires versatility—balancing the establishment of local capabilities with the development of scalable solutions that integrate seamlessly into global frameworks.

Commercial and Medical Affairs Systems

• Serve as the primary liaison between European Commercial (Sales, Marketing, Market Access) and Medical Affairs stakeholders and global Information Systems teams, fostering cross-functional collaboration while maintaining data governance and separation of processes.

• Partner with business leaders to develop prioritized roadmaps and capture requirements, ensuring alignment with global IT platform roadmaps while tailoring solutions to regional needs.

• Support rollout, localization, and adoption of global platforms (e.g., CRM, digital engagement, Omnichannel marketing, medical information, medical content management, field engagement tools).

• Partner with regional Commercial, Supply Chain and Quality teams to ensure IT systems supporting product distribution, logistics, and product release operate reliably and comply with regional regulatory standards.

• Oversee regional system enhancements, integrations, and facilitate compliance with regional and global regulations, including pharmacovigilance, promotional review, and data privacy.

• Provide Tier 1–2 application support in partnership with global support teams, ensuring seamless end-to-end service delivery.

• Lead change management for new IT systems, including user testing, training, communications, and stakeholder alignment to ensure successful adoption and continuous improvement.

Information Technology and Security

• Establish and manage relationships with regional managed service providers and vendors.

• Collaborate with global IT infrastructure teams to ensure reliable and secure delivery of core IT services (network, hardware, collaboration platforms, endpoint management).

• Manage onboarding and offboarding processes, ensuring timely provisioning/deprovisioning of accounts and devices aligned with regional and global IT policies and security standards.

• Ensure regional adherence to global IT service management and change control processes, including incident, request, and problem management, while coordinating escalations with global support teams.

• Partner with global Information Security teams to ensure adherence to enterprise security standards, policies, and regulatory requirements.

• Lead Europe-specific implementation and oversight of security controls—including identity and access management, data protection, compliance monitoring, cybersecurity training, audits, and incident response coordination with global security operations.

R&D Systems:

• Partner with global R&D IT to enable secure access to research and clinical platforms in compliance with regulatory requirements (GxP, GDPR, CTMS, EDC, RIM, eCTD, PV safety database, HIPAA etc).

Required Skills, Experience and Education:

• Proven leadership experience building and scaling IT teams in emerging regional operations, including recruitment, performance management, and fostering a culture of accountability and continuous improvement.

• Hands-on knowledge of IT infrastructure, end-user services, and cybersecurity practices.

• Strong understanding of Commercial data ecosystems (CRM, digital engagement, social, and third-party sources) and their integration across platforms.

• Knowledge of master data management (MDM), data warehousing principles and technologies, and enterprise analytics environments (e.g., Databricks, Snowflake), supporting Commercial and Medical insights.

• In-depth knowledge of GxP systems, regional regulatory, compliance, and data privacy frameworks and processes.

• Experienced in leading organizational change for IT initiatives, driving user adoption through clear communication, stakeholder alignment, and compelling storytelling.

• Collaborative and effective in building rapport across global, regional, and functional teams.

• Comfortable with ambiguity and skilled at defining operating models, processes, and roles while simultaneously implementing capabilities.

• Bachelor’s degree (or equivalent).

• Minimum of 12 years of experience delivering technology services and support, including Commercial systems.

• At least 4 years of experience leading regional IT activities within a life sciences organization

Preferred Skills:

• Experience supporting pre-commercial or commercial launches in pharma strongly preferred.

• Familiarity with Omnichannel principles and technology platforms in life sciences.

• Experience with an Oncology launch is desired.

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