Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
Dyne Therapeutics seeks a strategic and execution-oriented Executive Director, Corporate Development to lead external growth initiatives. Reporting to the Chief Business Officer (CBO), this role focuses on identifying and executing partnership and alliance opportunities aligned with Dyne’s neuromuscular focus and expansion of the FORCE platform into new therapeutic areas. The Executive Director, Corporate Development works closely with the CBO, Chief Innovation Officer, CSO, CFO, IR team, and other executives to drive strategic assessments and investor messaging.
The role can be remote with travel to Waltham, MA.
Key Responsibilities
Business Development Execution:
- Support and drive business development efforts including preparing pitch decks, engaging with counterparties, supporting due diligence, and negotiations.
- Lead term-sheet development and negotiation in collaboration with CBO, Legal and Finance.
- Coordinate cross-functional diligence efforts across scientific, clinical, CMC, commercial, and IP domains.
- Manage external advisors, data rooms, and timelines to ensure efficient transaction execution.
Strategic Planning:
- Define strategy and support indication assessments for Dyne’s initiatives to expand the reach of its FORCE platform beyond neuromuscular disease.
- Build market maps and identify strategic whitespace opportunities aligned with Dyne’s platform capabilities.
- Conduct competitive intelligence and landscape analysis to inform prioritization.
- Develop scenario models and strategic frameworks to evaluate new therapeutic areas and partnership opportunities.
Investor Messaging:
- Support messaging for key investor meetings by conducting deep analysis of the competitive landscape and Dyne’s position within it.
- Lead end-to-end execution of partnership and alliance transactions, including diligence, valuation, and negotiation.
- Maintain a prioritized pipeline of external opportunities aligned with Dyne’s strategy.
- Collaborate cross-functionally to integrate scientific, clinical, and commercial insights into deal assessments.
- Develop board-ready investment cases and strategic recommendations.
- Represent Dyne externally with potential partners, investors, and at industry events.
Qualifications
- 12+ years of experience in biotech/pharma corporate development, business development, strategy, or related fields.
- BA/BS required; MBA or advanced degree in life sciences (PhD/MD/PharmD) preferred.
- Proven track record of executing partnerships, alliances, and strategic transactions.
- Strong scientific literacy and ability to collaborate with R&D and innovation teams.
- Excellent communication skills and experience preparing investor-facing materials.
- Timeliness and effectiveness of partnership execution.
- Impact of strategic assessments on corporate direction.
- Quality and clarity of investor messaging and materials.
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
What We Do
Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne has a broad portfolio of programs for serious muscle diseases, including candidates for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com.
