Downstream Process Development Senior Scientist

Posted 7 Days Ago
Be an Early Applicant
Athens
In-Office
Senior level
Software • Pharmaceutical
The Role
The Senior Scientist will lead downstream process development projects, conduct experiments, and collaborate on scaling processes while ensuring regulatory compliance.
Summary Generated by Built In

At DEMO SA, one of the world’s largest pharmaceutical manufacturers in injectable facilities, our new Biotechnology Center in Athens, Kryoneri is now fully operational.

Biotechnology is transforming healthcare, and DEMO is at the forefront with cutting-edge research and innovation. As we continue to grow, we are looking for a high-caliber DSP Senior Scientist to join our team.

Main duties and responsibilities:

  • Plan and execute downstream process development projects, including chromatography and filtration strategies.
  • Design, plan, and perform experiments to identify Critical Process Parameters (CPPs) and their impact on Critical Quality Attributes (CQAs).
  • Apply advanced statistical and experimental design methodologies (e.g., DoE) to optimize process performance.
  • Conduct process characterization studies, such as viral clearance, resin reuse, and process limit evaluations.
  • Collaborate with cross-functional teams to scale processes from lab to pilot and commercial scale.
  • Author and review technical documentation, including development reports, protocols, and support regulatory submissions.
  • Provide technical support during technology transfer and scale-up.
  • Stay at the forefront of innovation by monitoring industry trends and integrating novel technologies into our workflows.

Requirements
  • PhD or MSc in Biochemical Engineering, Biotechnology, Biochemistry, or related field.
  •  5+ years of hands-on experience in downstream process development within the biopharmaceutical industry.
  • Expertise in chromatography, filtration, and process characterization techniques.
  • Strong grasp of DoE principles and statistical analysis tools (e.g., JMP, Minitab).
  • Experience with GMP environments, regulatory expectations, and tech transfer.
  • Excellent problem-solving skills and a passion for data-driven decision-making and a team player.

Benefits

The Company offers competitive remuneration, continuous learning and development opportunities, and a friendly and challenging working environment.

Top Skills

Chromatography
Doe
Filtration
Jmp
Minitab
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The Company
HQ: Krioneri
849 Employees

What We Do

DEMO is a dynamic Greek industrial and commercial organization, specializing in the development, production and supply of pharmaceutical products.
The company is the largest supplier of injectables for public hospitals in Greece, exports 80% of its annual production and is recognized as one of the official suppliers of the United Nations, UNICEF, the World Health Organization (WHO), Doctors Without Borders and the International Committee of the Red Cross. With over 3,300 circulation licenses in 86 countries worldwide, the largest factory in SE Europe and over 1,400 employees, DEMO paves the way for pharmaceutical self-sufficiency for Greece and Europe.
Today, DEMO implements investments of €356 million, strengthening production and R&D, while entering the development and production of active ingredients and Biotechnology.
At the same time, the company is committed to ensuring equality, diversity and inclusion in the working environment and has adopted -within this context- the Diversity Charter for Greece.
DEMO moves "Always Forward" driven by its corporate philosophy of providing quality and reliable pharmaceutical products, for everyone.

Learn more at www.demo.gr

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