Downstream Process Development Scientist

Job Description:

At Ferring Pharmaceuticals, we help people around the world build families and live better lives. We are entrepreneurial and innovative, with a global team focused on scientific advances in the areas of reproductive and women’s health, gastroenterology and urology. Ferring + You is all about working together and sharing ideas, so that we can bring science to life for patients around the world.

Joining our R&D teams North of Lausanne, Switzerland, you will discover an empowering culture and the opportunity to create and deliver innovative products that have the potential to change lives. Collaborating with colleagues inside and outside Ferring, we are focused on growing our capabilities with new therapeutics, life-cycle management and personalized solutions. Doing revolutionary work is in your hands.

Ferring+You

Ferring Biologics Innovation Center (FBIC), at Biopôle Epalinges, is looking for a Scientist to join the DSP Development team.

As part of the Ferring strategy to strengthen its portfolio of Biologics, you are involved in the Biologics DSP development activities including process development, DSP characterization and validation, DSP scale-up, technology transfer, DSP platform improvement and new technologies investigations.

As a FBIC team member, you are joining an international, dedicated and engaged team where your input will be highly valued and where open communication is crucial. Take benefit of a brand new and state-of-the-art lab ideally situated in the beautiful Lake Geneva region.

Your day at Ferring

• With a Quality by Design (QbD) approach in mind and by using state-of-the-art equipment (e.g. ÄKTA Pure, Krosflo FS-15 etc.), perform process development activities including membrane/resin chromatography and filtration (NFF and TFF) experiments to develop robust and lean Biologics processes fit for technology transfer to CMO and clinical material generation

• Be involved in the implementation of the pilot scale DSP capacity and perform pilot scale activities (200 L batch purification)

• Analyze data, report results and progress to the head of DSP and team, troubleshoot and propose a way forward

• Write and/or review laboratory-related and DSP-related SOPs, work instructions and protocols in English

• Write and/or review experimental reports, development/tech transfer reports, meeting minutes and presentations in English

• Be involved in the implementation of the Quality systems, the procedures and the instructions supporting IND/BLA submissions

• Be accountable for lab area and equipment. Make sure that equipment is maintained and calibrated. Make sure that stock of chemicals/consumables is at right level

• Propose means for process and yield improvements, including the use of new technologies

• Implement lean tools in the lab such as 5s at the bench

Behind our innovation…There’s you

• Experience in the purification of Biologics and acquired knowledge of purification process development is a must have. Examples of relevant experience are resin screening, Design of Experiment (DOE) approach, viral inactivation/filtration, UF/DF development, etc. Experience of designing a process for highly concentrated solution is a plus

• Experience in pilot-scale activities is a plus

• Experience in purification process development of viral vectors is a plus

• Experience with robotic platform (Tecan) and/or modelling (GoSilico) is a plus

• Master’s degree (or equivalent relevant experience) in bioprocess/pharmaceutical sciences field

• At least 8 years of hands-on experience in using chromatography and filtration equipment, > 10 years preferred

• Communicate orally and in writing fluently in English

• Knowledge of the Quality requirements (GLP/GMP) related to CMC development activities of biologics

• Experience in regulatory interactions is a plus

• Strong ability and passion to work in a collaborative manner

People come first at Ferring

• Get inspired from our commitment to advocate for everyone’s right to build a family, no matter who you are, where you live or who you love

• Our inclusive support package – “Building Families at Ferring” provides equal and accessible policies for all employees who wish to start their family journey, ensuring a global standard, irrespective of location and role

• Parental leave for both birthing and non-birthing parents

• Extended support on family building journey

Making a difference in the life of millions of people means we succeed by working together. Our diverse backgrounds, experiences, expertise, and perspectives enable us to find solutions to even the most challenging problems, and our success is tied to each team member’s contributions. Imagine the power of your career when it’s Ferring + You.

Behind our purpose… There’s you

If our mission and your vision are aligned, please apply!

We strive to build and maintain an inclusive and diverse workplace with equal opportunities and mutual respect for all employees regardless of their backgrounds and socioeconomic status.

Location:Switzerland HQ - St-Prex