Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.
Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.
Position Overview
We are looking for a Director or Senior Director of Organizational Development to help shape how Flagship grows, evolves, and thrives. Reporting to the VP of Talent Development, you'll build the talent, leadership, and organizational capabilities that enable our science-driven enterprise to scale with purpose.
Key ResponsibilitiesTalent Management & Development
- Design and evolve Flagship's talent management framework, including performance management, succession planning, career development, talent reviews, coaching, mentoring, and leadership development.
- Foster a culture of continuous feedback and development supported by modern talent technologies and AI-enabled solutions.
- Build career pathways and talent mobility programs that strengthen employee growth, retention, and organizational capability.
Organizational Development & Change
- Build scalable organizational development and change management frameworks, tools, and playbooks.
- Partner with senior leaders to lead change initiatives, strengthen leadership capability, and improve organizational effectiveness.
- Develop change readiness, stakeholder engagement, and communication strategies that support successful transformation.
Strategic Communications & Program Leadership
- Partner with HR, Communications, and business leaders to deliver clear, engaging communications that support organizational initiatives.
- Lead a portfolio of high-impact OD programs from strategy through implementation, using data and analytics to measure success and continuously improve outcomes.
- Align stakeholders, priorities, budgets, and resources across multiple concurrent initiatives.
- 8+ years of experience in Organizational Development, Talent Management, Learning & Development, or a related HR discipline.
- Proven success designing and scaling talent management programs, career development frameworks, and continuous feedback cultures.
- Hands-on experience leading enterprise change management initiatives; Prosci, Kotter, or similar methodology is a plus.
- Strong program and project management skills, with the ability to manage multiple strategic initiatives in a matrixed organization.
- Experience using modern talent management platforms (e.g., Workday, Lattice, Culture Amp, 15Five) and leveraging people analytics to drive decisions.
- Experience in biotech, life sciences, pharmaceuticals, venture capital, or another innovation-driven environment is preferred.
- Exceptional communication, collaboration, and influencing skills, with the ability to build trust across all levels.
- Strategic, hands-on leader who thrives in ambiguity and enjoys building new capabilities.
- Bachelor's degree or equivalent experience; advanced degree or HR/change management certification is a plus.
- Ability to work in our Cambridge, MA office four days per week.
Why Flagship Pioneering
This is a role for a builder — someone energized by creating what does not yet exist, inside one of the most consequential innovation organizations in the world.
- Everything we build is oriented around improving human health and the health of our planet. The organizational systems you design will directly accelerate that mission.
- You will shape OD practices across an enterprise and its entire ecosystem of platform companies — rare scope for any practitioner.
- You will partner with world-class scientists, entrepreneurs, and capital managers. Curiosity and bold thinking are expected and celebrated.
- This role sits at the intersection of strategy and execution, with direct partnership with senior leadership.
- As Flagship grows, so does this function. There is genuine opportunity to expand your team and deepen your impact over time.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
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Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected].
The salary range for this role is $172,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected].
Skills Required
- 8+ years of experience in Organizational Development, Talent Management, Learning & Development, or related HR discipline.
- Proven success designing and scaling talent management programs, career development frameworks, and continuous feedback cultures.
- Hands-on experience leading enterprise change management initiatives.
- Experience using modern talent management platforms (Workday, Lattice, Culture Amp, 15Five) and leveraging people analytics.
- Strong program and project management skills; ability to manage multiple strategic initiatives in a matrixed organization.
- Exceptional communication, collaboration, and influencing skills.
- Strategic, hands-on leadership and comfort with ambiguity while building new capabilities.
- Bachelor's degree or equivalent experience.
- Ability to work in Cambridge, MA office four days per week.
- Experience with Prosci, Kotter, or similar change management methodology.
- Experience in biotech, life sciences, pharmaceuticals, venture capital, or other innovation-driven environment.
- Advanced degree or HR/change management certification.
Flagship Pioneering Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Flagship Pioneering and has not been reviewed or approved by Flagship Pioneering.
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Fair & Transparent Compensation — Feedback suggests salary bands are visible for many Boston/Cambridge roles and pay is considered competitive for key scientific and leadership positions. Transparency in postings supports expectations that offers align with local biotech norms.
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Healthcare Strength — Feedback suggests medical, dental, vision, disability, life insurance, HSA options, and mental-health coverage are comprehensive and well-regarded. Multiple items are employer-verified, reinforcing confidence in core health benefits.
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Parental & Family Support — Feedback suggests maternity/paternity leave and family leave are offered at meaningful levels. These programs sit alongside paid holidays, sick days, and PTO to support family needs.
Flagship Pioneering Insights
What We Do
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique, hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.5 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions. The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).









