Alkermes is seeking an experienced Program Manager to support our ALKS 2680 program which is currently in Phase 2 development and preparing for Phase 3 and registration. ALKS 2680 is a novel, investigational, oral, selective orexin 2 receptor (OX2R) agonist in development as a once-daily treatment for narcolepsy and idiopathic hypersomnia. This person will work closely with members across our organization including areas such as research, pre-clinical, clinical, pharmaceutical development, regulatory affairs, medical affairs, commercial, operations, policy and government affairs, patient engagement and corporate communications, as well as the senior management team to orchestrate development and execution of our fully-integrated program strategic and operational plans to support key corporate goals including the development and ultimate approval of ALKS 2680 as well as identify and execute a comprehensive lifecycle management program.
This is a hybrid on-site position based at our Waltham, MA office.
Areas of responsibility will include:
- Facilitates development and execution of fully-integrated program strategic and operational plans, including:
- Development of program strategy, business objectives, activities to achieve these, and potential constraints with team recommendations for how to address
- Identifies cross-functional linkages/potential gaps, supports team with optimization of plans and execution
- Given the phase of this program the ideal candidate will have previous experience with late-stage development and registration submission preparation and support
- Proactive management of project execution as well as facilitating and maintaining comprehensive risk management plans
- Provides strong project management support to ensure issues are resolved by the team and communication / escalation is executed as needed
- Facilitates an innovative solution-oriented mindset and transparency across the business
- Facilitates an enterprise mindset within the team and drives strong cross-functional prioritization and decision making
- Development of program strategy, business objectives, activities to achieve these, and potential constraints with team recommendations for how to address
- Provides leadership and overall program management support to the product team and key sub-teams
- Development and maintenance of program budgets, timelines, and communication tools/documents used by the team and senior management to ensure strong communication and integrated logistical operations across the business
- Contributes to enhancement and innovation of program management systems and processes to support the evolving needs of our teams and the broader organization
We’re looking for an individual who values the team dynamic, is organizationally savvy, excels in a matrixed-management/leadership environment, and enjoys working on the details without losing site of the larger organizational goals.
Basic Requirements:
- BS/MS in a scientific or engineering discipline, with 12+ years of relevant pharmaceutical product development experience
Preferred Requirements:
- Prior experience managing product teams across the drug product lifecycle continuum from early-stage through late-stage candidate development, as well as commercial and lifecycle management; including support and maintenance of program strategic plans as well as product timeline and budgetary management responsibility
- Prior experience working on regulatory submissions
- Expert knowledge of MS Project, MS Excel; knowledge of Planview and SmartSheet would be beneficial
- Exceptional verbal/written communication, time/resource management, attention to detail, interpersonal and organization skills
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QualificationsThe annual base salary for this position ranges from $212,000 to $240,000. In addition, this position is eligible for an annual performance pay bonus. Exact compensation may vary based on skills, training, knowledge, and experience. Alkermes offers a competitive benefits package. Additional details can be found on our careers website: www.alkermes.com/careers#working-here
About UsWhy join Team Alkermes?
Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts’ Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.
Skills Required
- BS or MS in a scientific or engineering discipline
- 12+ years of relevant pharmaceutical product development experience
- Prior experience with late-stage development and registration submission preparation and support
- Prior experience managing product teams across the drug product lifecycle, including timeline and budget management responsibility
- Prior experience working on regulatory submissions
- Expert knowledge of MS Project and MS Excel
- Knowledge of Planview and SmartSheet
- Exceptional verbal and written communication, time/resource management, attention to detail, interpersonal and organization skills
What We Do
Alkermes focuses on the development of innovative medicines that seek to address unmet needs of people living with serious mental illness, addiction, and cancer. As a fully-integrated, global biopharmaceutical company, we apply our scientific expertise and proprietary technologies to develop products that are designed to make a meaningful difference in the way patients manage their disease. We are inspired by some of the most pressing public health challenges of our time to help advance innovation with the potential to improve treatment options and outcomes for patients. Beyond our important mission of developing medicines, we believe it is our responsibility to take a holistic approach as we seek to support patients, caregivers, and broader impacted communities. In this context we also work to help support and enhance the systems through which these complex diseases are treated. We are committed to patient engagement, disease education and awareness, and advocacy for important policies that support equitable access to quality treatment. Headquartered in Dublin, Ireland, we have an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. See our Community Guidelines: https://www.alkermes.com/social-community-guidelines
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