Director, HTA, Value & Evidence, Lung Cancer

Posted 12 Hours Ago
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3 Locations
In-Office or Remote
177K-294K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Leads U.S. health technology assessment, value, and evidence strategy for Pfizer’s lung cancer and precision medicine portfolio. Oversees HEOR, real-world evidence, economic modeling, patient-reported outcomes, evidence generation, publications, AMCP dossiers, and payer-facing materials. Collaborates with global, medical, market access, commercial, alliance, academic, and external stakeholders to support reimbursement, appropriate use, and patient access. Requires advanced expertise in health economics, epidemiology, healthcare research, oncology, project management, and U.S. healthcare policy.
Summary Generated by Built In
ROLE SUMMARY
The Director, HTA, Value & Evidence (HV&E), US, Lung Cancer will support the strategic goals of the Oncology Division by driving optimal patient access & appropriate use of medicines within the lung cancer & precision medicine portfolio.
This role directly impacts the ability to achieve business objectives on a US basis by providing strategic guidance and robust evidence development relevant to achieve appropriate use by providers and optimal patient access by demonstrating the value of our medicines. The HV&E Director will be responsible for developing and executing against the US evidence generation strategy, including direct oversight of evidence generation activities and dissemination of technical deliverables, in collaboration with Global HV&E and US Medical.
This position will work closely with Global HVE, GASP, cross-functional US teams, and cross-company alliance partners to foster a culture that promotes innovation, collaboration and thrives on doing better for Pfizer's patients and for US healthcare providers and systems.
ROLE RESPONSIBILITIES
  • Lead the development of the evidence generation strategy to support the value of medicines in the lung cancer & precision medicine portfolio in the Oncology Division in close partnership with the cross-functional matrix team.
  • Lead the coordination of input from US Medical, field-facing colleagues, US Market Access, cross-alliance partners and GASP and USMA team on evidence needs and ensure that the input is appropriately incorporated to develop and integrate the evidence strategy to support market access needs at launch and through lifecycle.
  • Lead the design and execution of HEOR studies (eg, network meta-analyses, Real World Evidence studies such as non-interventional studies), including studies involving site engagement, chart abstraction, and retrospective data collection, from concept through publication.
  • Lead the timely development of US value & evidence strategy in coordination with US Medical, Global HV&E, customer-facing deliverables such as AMCP dossiers, systematic literature reviews, economic models, and innovative tools to successfully support reimbursement and access requirements in conjunction with US customer facing teams.
  • As needed, provide strategic input into clinical trial designs (eg, patient populations, comparators, endpoints) and analysis and interpretation of PRO data to enable successful differentiation negotiations, reimbursement, and appropriate patient access with US payers, and regulatory decision makers.
  • Partner with internal & cross-alliance stakeholders to ensure appropriate customer facing dissemination of HEOR materials per regulatory guidance and internal SOPs, including development of PVPs, promotional materials and FDAMA 114 compliant materials.
  • Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.

BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
  • Graduate degree minimum (e.g. MSc, MPH, PhD) required
  • 7+ years of experience required with MSc/MPH/MBA degree; 5+ years of experience required with PharmD/PhD in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
  • Demonstrated in depth understanding of fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation. Capable of independently managing complex non-interventional study projects
  • Knowledge and understanding of drug development process and the US healthcare /economic environment.
  • Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
  • Excellent oral and written English communication skills
  • Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to business priorities and prioritize accordingly
  • An "execution mindset" focused on getting things done quickly and simply
  • Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
  • Ability to influence key members of medical, clinical, cross-alliance and commercial teams constructively and without conflict
  • Skilled in functioning within a matrix organization by managing through influence
  • Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize & address/resolve
  • Change oriented, comfortable responding to unexpected demands with tight timelines; team player

PREFERRED QUALIFICATIONS
  • Demonstrated ability to manage and oversee real-world evidence studies involving clinical sites, medical record review, chart abstraction vendors, data quality oversight, protocol-aligned abstraction processes, and operational execution from study start-up through analysis and reporting is preferred.
  • Knowledge and experience in the oncology therapeutic area with lung cancer experience preferred.
  • Experience with the US healthcare environment.
  • Experience with HTA organizations/submissions such as ICER, CMS-IPAY (IRA) and other HTA groups such as NICE.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
  • Ability to travel domestically and internationally based on business needs
  • Ability to work in all US time zones

Other Job Details:
  • Last Date to Apply for Job: September 01, 2026
  • NOT Eligible for Relocation Package
  • Position is hybrid and will require to work 2/3 days a week from site
The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Market Access

Skills Required

  • Graduate degree, such as MSc, MPH, or PhD
  • At least 7 years of experience with an MSc, MPH, or MBA in HEOR or a related field
  • At least 5 years of experience with a PharmD or PhD in HEOR or a related field
  • In-depth knowledge of health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies
  • Ability to independently manage complex non-interventional study projects
  • Knowledge of the drug development process and U.S. healthcare and economic environment
  • Excellent interpersonal, oral, and written English communication skills
  • Ability to assess project and program value against business priorities
  • Strong project management skills, including contracting, budgeting, vendor management, multitasking, and managing competing deadlines
  • Ability to influence medical, clinical, cross-alliance, and commercial teams constructively
  • Experience functioning effectively within a matrix organization and managing through influence
  • Organized, detail-oriented, proactive, and able to anticipate and resolve needs
  • Ability to adapt to change, unexpected demands, and tight timelines
  • Ability to travel domestically and internationally based on business needs
  • Permanent U.S. work authorization and authorization to work for any U.S. employer
  • Experience overseeing real-world evidence studies involving clinical sites, medical record review, chart abstraction vendors, data quality, and operational execution
  • Oncology therapeutic-area knowledge, preferably lung cancer experience
  • Experience with the U.S. healthcare environment
  • Experience with HTA organizations and submissions, including ICER, CMS-IPAY, IRA, or NICE

What the Team is Saying

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Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Official materials describe comprehensive medical, dental, vision, and mental-health support, plus fertility/family‑building and transgender‑inclusive coverage; eligible Pfizer medications are noted as available at no cost in U.S. plans. Wellness resources such as telehealth and preventative programs are also emphasized.
  • Retirement Support Company documents highlight a 401(k) with matching contributions plus an additional Retirement Savings Contribution beyond the match. Financial planning support and company‑paid life and disability insurance further bolster long‑term security.
  • Leave & Time Off Breadth Corporate pages and job postings describe paid vacation and holidays, caregiver leave, and paid parental leave for both parents. Materials also note that details can vary by role and location.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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