Director, HTA, Value & Evidence (HV&E) - Obesity

Posted Yesterday
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29 Locations
In-Office or Remote
177K-294K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Lead global HEOR and evidence-generation strategy for obesity assets. Design and execute RWE, economic models, and PRO strategies; create launch dossiers; manage cross-functional teams, vendors, budgets, and external partnerships to support reimbursement and patient access.
Summary Generated by Built In
Use Your Power for Purpose
As a leading biopharmaceutical company, Pfizer is dedicated to the discovery and delivery of high value therapies across a variety of disease areas. It is our mission to bring innovative medicines to patients that significantly improve their lives, and our priority is to ensure patients have access to these medicines.
The Health Technology Assessment (HTA), Value & Evidence (HV&E) team is responsible for ensuring patients have affordable, timely access to medicines and vaccines by advancing innovative value and evidence solutions to inform healthcare decision-making.
The Director, HTA, Value & Evidence (HV&E) - Obesity will support the strategic goals of the Primary Care Division by driving optimal patient access for Pfizer's portfolio of Obesity products.
This role influences global business objectives by guiding strategic evidence development to ensure optimal patient access for Obesity treatments. The HV&E Director will be responsible for developing and executing against the global evidence generation strategy, including direct oversight of evidence generation activities and dissemination of technical deliverables.
This position will be part of Pfizer's dynamic Global HTA Value and Evidence team and will have the important role of managing health economics and outcomes research (HEOR) to generate data to support patient access to Obesity treatments. This position will be working closely with the Primary Care Global Access Strategy and Pricing (GASP) team, US Market Access team, cross-functional and country teams to foster a culture that promotes innovation and thrives on doing better for Pfizer's patients and society in general.
What You Will Achieve
In this role, you will:
  • Lead the development of the evidence generation strategy to support the value of internal medicine assets (focus on Obesity treatments) in the Primary Care Division, in close partnership with the cross-functional matrix team (e.g., medical, commercial, access strategy/pricing, statistics, clinical).
  • Lead the coordination of input from local country/regional teams on evidence needs and ensure that the input is appropriately incorporated into the evidence strategy to support global market access needs at launch and through lifecycle.
  • Lead the design and execution of global HEOR studies (e.g., network meta-analyses, non-interventional studies, economic models) from concept through publication.
  • Lead the timely development of launch deliverables including value & evidence strategy, global value dossiers/AMCP/JCA dossiers, systematic literature reviews, economic models, and innovative tools to successfully support reimbursement and access requirements in partnership with the regions/countries.
  • Develop patient-reported outcomes strategy and incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence aligned with overall asset strategy and to ensure global reimbursement and access requirements.
  • Provide strategic input into clinical trial designs (e.g., patient populations, comparators, endpoints) and analysis to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.
  • Partner with internal stakeholders to ensure appropriate customer-facing dissemination of HEOR materials per regulatory guidance and internal SOPs
  • Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.

Basic Qualifications:
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
  • Graduate degree required (e.g. MSc, MPH, PhD)
  • 7+ years of experience with MSc/MPH/MBA degree; 5+ years with PharmD/PhD/DrPH in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
  • Expertise in HEOR strategy, evidence development, fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation.
  • Capable of independently managing complex non-interventional study projects
  • Knowledge and understanding of drug development process
  • Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
  • Excellent oral and written English communication skills
  • Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to business priorities and prioritize accordingly
  • An "execution mindset" focused on getting things done quickly and simply
  • Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities and expertise in stakeholder engagement
  • Leadership in cross-functional teams (e.g. influence medical, clinical, and commercial teams constructively and without conflict); strategic thinking, and ability to guide junior team members
  • Skilled in functioning within a matrix organization
  • Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize & address/resolve
  • Change oriented, comfortable responding to unexpected demands with tight timelines

Bonus Points If You Have (Preferred Requirements):
  • Knowledge and experience in the Obesity therapy area
  • Experience with HTA organizations such as NICE, CADTH, PBAC, ICER and other HTA groups
  • Experience in supporting global Obesity launch
  • Experience with developing evidence strategies to optimize access in both the reimbursement and cash-pay / direct-to-consumer channels
  • Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use

OTHER JOB DETAILS:
  • Last Date to Apply for Job: August 27, 2026
  • Ability to travel travel domestically and internationally
  • Ability to work in all US time zones
  • Location: US any Pfizer site or Europe any Pfizer site
  • NOT eligible for Relocation Package
  • This position is hybrid and requires working onsite 2 to 3 days per week
The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Market Access

Skills Required

  • Graduate degree required (e.g., MSc, MPH, PhD)
  • 7+ years (MSc/MPH/MBA) or 5+ years (PharmD/PhD/DrPH) in HEOR or related fields
  • Expertise in HEOR strategy, evidence development, health economic modeling, PROs, statistics, and RWE/observational study methods
  • Ability to independently manage complex non-interventional study projects
  • Knowledge and understanding of the drug development process
  • Excellent interpersonal skills and ability to engage internal and external stakeholders
  • Excellent oral and written English communication skills
  • Ability to assess anticipated value and align projects to business priorities
  • Execution mindset focused on delivering results quickly and simply
  • Strong project management skills (contracting, budgeting, vendor management) and ability to manage multiple complex projects
  • Leadership in cross-functional teams and ability to guide junior team members
  • Experience functioning within a matrix organization
  • Organized, detail oriented, and able to anticipate needs proactively
  • Comfortable with change and working under tight timelines
  • Knowledge and experience in the Obesity therapy area
  • Experience with HTA organizations (e.g., NICE, CADTH, PBAC, ICER)
  • Experience supporting global Obesity launch
  • Experience developing evidence strategies for reimbursement and cash-pay/direct-to-consumer channels
  • Experience using AI tools (generative technologies such as ChatGPT or Microsoft Copilot) and understanding responsible AI practices

What the Team is Saying

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Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Official materials describe comprehensive medical, dental, vision, and mental-health support, plus fertility/family‑building and transgender‑inclusive coverage; eligible Pfizer medications are noted as available at no cost in U.S. plans. Wellness resources such as telehealth and preventative programs are also emphasized.
  • Retirement Support Company documents highlight a 401(k) with matching contributions plus an additional Retirement Savings Contribution beyond the match. Financial planning support and company‑paid life and disability insurance further bolster long‑term security.
  • Leave & Time Off Breadth Corporate pages and job postings describe paid vacation and holidays, caregiver leave, and paid parental leave for both parents. Materials also note that details can vary by role and location.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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