Director, External Science Lead, Biologics Discovery and Design

Posted 3 Hours Ago
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Cambridge, MA, USA
In-Office
177K-294K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Lead sourcing, evaluation, and partnership execution for external biologics discovery, protein engineering, and AI/ML-enabled design platforms. Build cross-functional diligence teams, drive RU alignment, shepherd opportunities through governance and BD/legal, and represent Pfizer externally to integrate innovative platforms into internal workflows for portfolio impact.
Summary Generated by Built In
ROLE SUMMARY
Discovery Network (DN), External Science Lead Biologics Discovery and Design supports Pfizer's broad strategic objectives which include creating a future R&D ecosystem where internal capabilities and science blend with external innovation and where breakthrough ideas can develop into differentiated medicines.
You will facilitate the evaluation and application of innovative biologics discovery and design platforms to strengthen Pfizer R&D pipeline. As part of the Preclinical & Translational Sciences (P&TS) and the Discovery Network (DN) team you will partner closely with BioMedicine Design (BMD) and engage the global life sciences ecosystem (academia, biotech, venture, and consortia) to source and advance technologies spanning protein therapeutic discovery, design, optimization and early developability, including AI/ML-enabled approaches. You will work closely across all Research Units (RUs) to ensure broad applicability and portfolio impact, leading diligence, governance, and partnership execution aligned with strategic priorities.
ROLE RESPONSIBILITIES
  • Lead global networking and sourcing of external biologics discovery and protein engineering technologies
  • Identify and evaluate AI/ML-enabled platforms for protein design, structure prediction, and design-make-test workflows
  • Partner with Bio-Molecular Design to define high-impact use cases and integration pathways into internal workflows
  • Drive alignment and adoption across all Research Units (RUs) and partner lines
  • Build and lead cross-functional diligence teams to evaluate scientific and strategic fit
  • Shepherd prioritized opportunities through governance and deal processes with BD and Legal
  • Leverage internal capabilities to position Pfizer as partner-of-choice and enable collaboration success
  • Represent Pfizer externally at key biologics and platform technology forums

MINIMUM QUALIFICATIONS
  • PhD or similar advanced degree with 5+ years of relevant industry experience, including significant experience in biologics discovery, protein engineering, or related discipline
  • Experience in business development, alliance management, or technology partnerships
  • Knowledge of early developability and biologics optimization considerations
  • Experience evaluating external scientific opportunities and driving prioritization
  • Experience working in cross-functional, matrix organizations
  • Strong communication skills, verbal, written and presentation, with experience communicating to different business groups/lines influencing senior stakeholders
  • Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity

PREFERRED QUALIFICATIONS
  • Experience in pharmaceutical drug development (Idea to Candidate) process.
  • Previous experience in biotechnology companies and/or venture investment.
  • Experience in process development, formulation, or drug product technologies

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Travel to partnering conferences, scientific meetings, Pfizer and collaborator sites required app. 20% of time
Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.
Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use.
The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Bus Dev & Strategic Planning

Skills Required

  • PhD or similar advanced degree with 5+ years relevant industry experience in biologics discovery, protein engineering, or related discipline
  • Experience in business development, alliance management, or technology partnerships
  • Knowledge of early developability and biologics optimization considerations
  • Experience evaluating external scientific opportunities and driving prioritization
  • Experience working in cross-functional, matrix organizations
  • Strong verbal, written, and presentation communication skills with ability to influence senior stakeholders
  • Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot
  • Experience in pharmaceutical drug development (Idea to Candidate) process
  • Previous experience in biotechnology companies and/or venture investment
  • Experience in process development, formulation, or drug product technologies
  • Demonstrated leadership experience including influencing peers, coaching others, and overseeing colleagues to achieve outcomes

What the Team is Saying

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Pfizer

Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Multiple U.S. medical plan options include telehealth, comprehensive mental‑health support, fertility/family‑building benefits, transgender‑inclusive coverage, and certain Pfizer medications at no cost. A Wellbeing Wallet and wellness resources broaden the health and wellbeing offering.
  • Retirement Support A 401(k) with company matching is paired with an additional Pfizer Retirement Savings Contribution, alongside company‑paid life and disability insurance. One‑on‑one financial planning support is provided through Fidelity.
  • Leave & Time Off Breadth Paid time off spans vacation, holidays, and personal days, with additional caregiver and medical leave. U.S. parental leave commonly includes 12 weeks paid with options for additional unpaid bonding time and a return‑to‑work transition.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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