Director, End to End Portfolio Lead
Location: Pearland, TX (On-site)
This on-site leadership role in Pearland, TX drives critical site-wide investment and transformation initiatives, including ownership of a flagship 3D Filler CAPEX project. You will play a pivotal role in shaping long-term site strategy, enabling successful new product introductions, and ensuring operational excellence during a high-impact growth phase.
What you will get:
A competitive compensation. In addition, below you will find a comprehensive summary of the benefits package we offer:
Performance-related bonus.
Medical, dental and vision insurance.
401(k) matching plan.
Life insurance, as well as short-term and long-term disability insurance.
Employee assistance programs.
Paid time off (PTO).
Compensation for this role will be determined by the candidate’s qualifications, skills, experience, and relevant knowledge.
What you will do:
Lead end-to-end ownership of critical site CAPEX projects, including the 3D Filler program, with accountability for scope, cost, schedule, and business outcomes.
Translate site strategy into executable project roadmaps that deliver revenue growth, profitability, and long-term operational capability.
Build and lead cross-functional teams across Engineering, Operations, Quality, Procurement, HR, and Commercial to deliver complex initiatives.
Develop and validate project charters, business cases, and capital authorization requests, ensuring strategic, technical, and financial alignment.
Drive operational readiness by ensuring early integration of operations, process knowledge, and organizational capability during design and build phases.
Proactively manage project risks and issues, escalating to Steering Committee and Leadership Teams as required.
Partner with Quality and Customer Project Management to ensure cGMP compliance, successful PPQ, regulatory approval, and alignment with customer requirements.
What we are looking for:
Bachelor’s degree in biotechnology, biology, chemistry, engineering, business, project management, or a related field; a science or engineering discipline is preferred.
Demonstrated experience leading capital projects, project management initiatives, and/or operational excellence programs in complex environments.
Solid background within pharmaceutical, CDMO, or regulated manufacturing operations.
Strong understanding of GMP-regulated manufacturing and safe work environments.
Proven leadership experience, including leading cross-functional teams and driving accountability for results.
Ability to translate strategy into execution, balancing technical, operational, and business priorities.
Experience building organizational capability and supporting continuous improvement in a multi-layered organization.
About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.
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What We Do
At Lonza, we enable A Healthier World by supporting our healthcare customers on the path to commercialization. Our community of 16,000 talented employees work across a global network of more than 30 sites to deliver for our customers across the pharma, biotech and nutrition markets.
