Director Clinical Bioinformatics

Posted 9 Days Ago
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Hiring Remotely in San Diego, CA, USA
In-Office or Remote
205K-308K Annually
Expert/Leader
Healthtech • Biotech
The Role
Leads clinical bioinformatics for end-to-end assay and application solutions, including novel algorithms on the DRAGEN platform. Oversees regulated genomic and multi-omic product development, manages globally distributed teams and managers, partners with customers and key opinion leaders, and guides innovation and competitive strategy across oncology, genetics, and reproductive health applications.
Summary Generated by Built In
What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Illumina is seeking a Director of Clinical Bioinformatics to lead delivery of informatic solutions that power Illumina’s end-to-end solutions and assay informatics. We are looking for an experienced bioinformatics leader that is passionate about powering new applications with innovative new informatics approaches using Illumina sequencing and multi-omic technologies. This is a unique opportunity to be a core contributor to Illumina’s mission to unlock the power of the genome by creating our next application solutions and industry leading bioinformatic algorithms. 

Location: The ideal candidate is based in San Diego, CA or within California with the ability to travel to San Diego on a regular 

basis. 

Responsibilities 

• Lead bioinformatics for design, delivery, and validation of end-to-end assay and application solutions.  

• Innovate vigorously to deliver high value solutions to drive next wave of precision medicine and multi-omics applications 

• Responsible for design and implementation of novel bioinformatics algorithms on the DRAGEN platform 

• Build and manage relationships with external customers, partners, and key opinion leaders and represent Illumina externally 

• Develop program to proactively monitor, and tactically and strategically respond to competitive technologies  

Requirements 

• Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.

• Proven track record of successfully leading major multi-disciplinary product development projects from concept to commercial release 

• Extensive experience developing Bioinformatics algorithms for multiple technologies (NGS and microarray) and domain areas (oncology, genetics, and reproductive health) 

• Broad experience building regulated lab developed tests, distributed IVD products, or regulated instrument systems 

• Must effectively balance innovation roadmap with execution-oriented product development projects 

• Exceptional communication skills  

• Able to deliver result in uncertain and fast-paced environment  

• Results oriented leader with 5+ years leading globally distributed teams; must have experience managing managers 

 

#LI-REMOTE

 

 

The estimated base salary range for the Director Clinical Bioinformatics role based in the United States of America is: $205,100 - $307,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Skills Required

  • Bachelor's degree
  • At least 18 years of related experience
  • At least 10 years of management experience
  • Proven success leading major multidisciplinary product development projects from concept through commercial release
  • Extensive experience developing bioinformatics algorithms for NGS and microarray technologies
  • Experience across oncology, genetics, and reproductive health domains
  • Experience building regulated laboratory-developed tests, distributed IVD products, or regulated instrument systems
  • Ability to balance innovation roadmaps with execution-oriented product development
  • Exceptional communication skills
  • Ability to deliver results in uncertain and fast-paced environments
  • At least 5 years leading globally distributed teams
  • Experience managing managers

Illumina Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Illumina and has not been reviewed or approved by Illumina.

  • Healthcare Strength — Health coverage includes comprehensive medical (HMO/PPO), dental, vision, mental health, life, and disability insurance with options such as FSAs/HSAs and wellness resources. Offerings are described as robust across regions with customization in certain locations.
  • Leave & Time Off Breadth — Time-off programs include flexible schedules and remote work, PTO or flexible time off, paid holidays and sick leave, and volunteer time. Company-wide shutdowns during summer and winter add additional paid time away.
  • Parental & Family Support — Family-focused programs include fertility assistance, adoption assistance, and reproductive health support alongside family medical leave. Paid parental leave is provided, with specifics varying by country and employment status.

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The Company
HQ: San Diego, CA
7,400 Employees
Year Founded: 1998

What We Do

Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.

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