Job Description
Director, Business Engagement & Technology – Commercial Cell and Gene TherapyLocation: Hybrid or On-site
Company OverviewVertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. We focus on specialty markets where we have deep expertise in science, technology, and patient needs. At Vertex, our Data, Technology & Engineering (DTE) organization plays a critical role in accelerating business performance, enabling digital and AI transformation, and delivering scalable platforms that support innovation across the enterprise.
Role SummaryThe Director of Business Engagement & Technology will serve as the strategic technology leader supporting the Commercial CGT business unit. This role is responsible for shaping and executing the data, technology, and AI roadmap that enables the business to scale global operations effectively.
This leader will act as the primary DTE partner, ensuring strong alignment between business priorities and technology strategy. The role will drive portfolio planning, oversee project execution, and partner across teams to deliver business value through modern, scalable, and compliant technology solutions.
Key Responsibilities• Serve as a strategic technology partner for the Commercial Cell and Gene Therapy business unit.
• Define and lead the data, technology, and AI roadmap to support business growth and global operational scale.
• Act as the primary liaison and trusted advisor between the business and DTE.
• Shape, prioritize, and manage the project portfolio to align with strategic business goals and enterprise technology priorities.
• Oversee large project execution, ensuring delivery against scope, timeline, budget, and expectations
• Translate business strategies and operational needs into actionable technology initiatives and solution roadmaps.
• Partner with cross-functional stakeholders across DTE, Commercial, Supply Chain, Quality and others
• Identify opportunities to leverage data, digital platforms, and AI capabilities to improve decision-making, efficiency, and business outcomes.
• Drive governance, planning, and communication processes for technology investments and program delivery.
• Ensure solutions are scalable, secure, compliant, and aligned with enterprise architecture standards.
• Monitor evolving business needs, industry trends, and emerging technologies to continuously enhance the technology strategy.
• Build strong stakeholder relationships and influence decision-making at senior leadership levels.
Required Qualifications• Bachelor’s degree in Information Technology, Computer Science, Engineering, Business, or a related field; advanced degree preferred.
• Significant leadership experience in business engagement, technology strategy, digital transformation, or related roles.
• Demonstrated experience partnering with business leaders to define and deliver technology roadmaps tied to strategic outcomes.
• Proven success managing complex project portfolios and leading cross-functional technology initiatives.
• Experience overseeing project execution in a matrixed, global organization.
• Strong understanding of data, enterprise technology platforms, and AI-enabled business solutions.
• Ability to bridge business strategy and technical execution with strong communication and influencing skills.
• Experience serving as a primary business partner or relationship manager for technology functions.
• Strong organizational, prioritization, and decision-making skills.
• Ability to operate effectively in a fast-paced, highly collaborative environment.
Technical Skills Required• Technology roadmap development
• Data strategy and enablement
• AI and advanced analytics strategy
• Project portfolio management
• Program and project execution oversight
• Business relationship management
• Digital transformation leadership
• Cross-functional stakeholder management
• Enterprise technology planning
• Governance and prioritization frameworks
• Scalable global operations support
• Technology-business alignment
• Budget management
Preferred Skills• Experience supporting Commercial, Cell and Gene Therapy, or Hematology-focused business functions.
• Commercial technology and GxP system expertise, including experience with platforms such as Salesforce
• Familiarity with regulated industry environments such as biotechnology, pharmaceuticals, or healthcare.
• Experience with global technology deployments and change management.
• Strong understanding of enterprise data ecosystems, reporting, and analytics capabilities.
• Ability to identify and implement innovative digital and AI solutions that improve commercial effectiveness.
• Experience working within a Data, Technology & Engineering or similar enterprise technology function.
• Executive presence with the ability to communicate strategy, risks, and progress to senior stakeholders.
BenefitsVertex offers a competitive and comprehensive rewards package designed to support employees’ well-being, growth, and success. Benefits may include:
• Competitive base salary and incentive compensation
• Comprehensive medical, dental, and vision coverage
• Retirement savings programs
• Paid time off and company holidays
• Professional development and learning opportunities
• Wellness and employee assistance programs
• Inclusive and collaborative work environment
• Opportunities to contribute to transformative work that impacts patients globally
Pay Range:
$198,000 - $297,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Skills Required
- Bachelor's degree in Information Technology, Computer Science, Engineering, Business, or related field
- Advanced degree (e.g., MS, MBA, PhD)
- Significant leadership experience in business engagement, technology strategy, or digital transformation
- Demonstrated experience partnering with business leaders to define and deliver technology roadmaps tied to strategic outcomes
- Proven success managing complex project portfolios and leading cross-functional technology initiatives
- Experience overseeing project execution in a matrixed, global organization
- Strong understanding of data, enterprise technology platforms, and AI-enabled business solutions
- Ability to bridge business strategy and technical execution with strong communication and influencing skills
- Experience serving as a primary business partner or relationship manager for technology functions
- Strong organizational, prioritization, and decision-making skills
- Ability to operate effectively in a fast-paced, highly collaborative environment
- Technology roadmap development
- Data strategy and enablement
- AI and advanced analytics strategy
- Project portfolio management
- Program and project execution oversight
- Business relationship management
- Digital transformation leadership
- Cross-functional stakeholder management
- Enterprise technology planning
- Governance and prioritization frameworks
- Scalable global operations support
- Technology-business alignment
- Budget management
- Experience supporting Commercial, Cell and Gene Therapy, or Hematology-focused business functions
- Commercial technology and GxP system expertise, including Salesforce
- Familiarity with regulated industry environments such as biotechnology, pharmaceutical, or healthcare
- Experience with global technology deployments and change management
- Strong understanding of enterprise data ecosystems, reporting, and analytics capabilities
- Ability to identify and implement innovative digital and AI solutions that improve commercial effectiveness
- Experience working within a Data, Technology & Engineering or similar enterprise technology function
- Executive presence with ability to communicate strategy, risks, and progress to senior stakeholders
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
