At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome — one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing deep, hard science with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.
We are seeking a Accounting Operations Manager to serve as the bridge between operations and finance at Nautilus. This role will own the integrity of inventory transactions, operational financial controls, standard costing methodologies, and manufacturing variance analysis for our reagent, flow cell, and instrumentation product lines. You will work cross-functionally with operations, supply chain, procurement, and leadership to ensure our NetSuite ERP and inventory systems accurately reflect the economics of the business.
This is a highly hands-on role, ideal for someone who has operated in biotech, life sciences, medical device, or other regulated manufacturing environments where inventory and operational accounting are deeply intertwined. You will play a critical role in enabling scalable financial reporting, accurate gross margins, inventory visibility, and operational decision-making as Nautilus moves from pre-commercial to commercial stage.
This position will report to the Corporate Controller.
Responsibilities
Inventory & Operational Financial Controls
Own month-end inventory close processes across raw materials, work-in-process, and finished goods (reagent kits, flow cells, and instrument components)
Ensure timely and accurate closure of purchase orders, receipts, inventory transfers, and sales orders in NetSuite
Reconcile inventory movements, adjustments, yield loss, and scrap across Reagent and Flow Cell product lines
Partner with operations and supply chain teams to improve ERP transaction discipline and inventory accuracy
Maintain inventory subledger integrity and support reconciliation to the general ledger
Review inventory discrepancies, negative inventory balances, and operational exceptions
Support implementation and optimization of NetSuite workflows and inventory controls as Nautilus scales toward commercialization
Cost Accounting & Manufacturing Finance
Build and maintain standard costing methodologies for raw materials, packaging, labor, freight, contract manufacturing, and cold-chain storage
Develop and maintain product-level and batch-level COGS models for reagent kits, flow cells, and instrumentation
Create labor, freight, and materials standards and perform variance analysis against actuals, including quarterly standard cost validations and revaluations
Analyze purchase price variances, manufacturing variances, and gross margin drivers
Support pricing decisions and operational improvement initiatives through financial analysis
Partner with operations to improve yields, throughput, and cost efficiency
Reporting & Cross-Functional Support
Build operational finance KPIs and reporting dashboards for inventory and cost performance
Support forecasting, budgeting, and financial planning activities related to inventory and cost of goods sold
Assist with audit readiness, inventory procedures, and SEC/investor reporting
Maintain SOX 404 internal control documentation and procedures for inventory and cost accounting processes
Collaborate with leadership on scaling operational and financial infrastructure as the company moves from pre-commercial to commercial stage
Qualifications
6+ years of experience in manufacturing finance, cost accounting, inventory accounting, supply chain finance, or operational finance roles
Experience working in biotechnology, life sciences, medical device, diagnostics, or other regulated manufacturing environments (preferred)
Strong understanding of inventory accounting, standard costing, variance analysis, and operational financial controls
Experience with ERP systems such as NetSuite, SAP, or similar (NetSuite strongly preferred)
Advanced Excel / financial modeling capabilities
Ability to work cross-functionally with operations, procurement, and leadership teams
Comfortable operating in a fast-paced, early-stage biotech environment
#LI-MM1
Skills Required
- Minimum of 6+ years of related work experience in cost accounting, preferably in manufacturing or biotechnology.
- Degree in Finance or Accounting, or equivalent experience.
- Solid knowledge of GAAP related to inventory and COGS required.
- Experience working with enterprise financial systems (NetSuite is a plus).
- Strong analytical skills and proficiency in Excel.
What We Do
Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus (Nasdaq: NAUT) set about solving a vexing problem: how to bring true proteomics to the world in a way that accelerates therapeutic development, dramatically improves medical diagnostics, and makes personalized and predictive medicine a reality. The extraordinary team at Nautilus represents a wide spectrum of disciplines and expertise, including: protein chemists, chip designers, molecular biologists, data scientists, material scientists, biophysicists, optical engineers, microfluidics engineers, bioinformaticists, software engineers, and more. Nautilus is positioned to revolutionize proteomics, transform the way drugs are developed, and significantly improve the way human health is managed.
