Company Overview
Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.
Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.
This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.
The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts
Summary
We are seeking a highly collaborative and enthusiastic Corporate Counsel to partner and provide strategic, tactical and operational legal guidance. Reporting to the Vice President, Legal, the Corporate Counsel will be responsible for a wide range of contracts, including clinical trial, research, supply, and other strategic agreements. You be an integral part of the legal function and will play a key role in partnering with teams across the organization, particularly our clinical operations team and external clinical research organization. You will identify compelling risk allocation and intellectual property concerns and convey them in business-first terms to the appropriate internal stakeholders. You will play a key role in corporate transactions, including collaborations, licensings, financings, strategic alliances, and M&A, as needed. Additionally, you will support a growing legal team with a wide variety of operational goals, including scaling the department and establishing processes and procedures, This role offers a broad range of responsibilities and significant growth opportunities in an exciting and growing company
Your Role:
Contracting and Transactions:
- Draft, review, and negotiate the company’s wide array of contacts for departments across the organization (including MSAs, CTAs, Consulting Agreements, etc.
- Provide business partnership to the clinical operations organization as a legal subject matter expert on contract interpretation and related legal best practices
- Support corporate transactions, including mergers, acquisitions, divestitures, investments, joint ventures, financings, and strategic alliances, as applicable
- Provide sound contract management, achieve company goals, and comply with company policies
- Assess contracts to determine risk levels and advising internal stakeholders on the same
- Continually improve the contracting process to ensure efficiency and provide internal education on legal policies and procedures
General:
- Support the legal department operations by developing and refining legal processes and policies and communicating such practices to the internal business teams
- Research legal matters relevant to the business as needed
- Partner closely with outside counsel, provide timely, pragmatic, and strategic advice on a wide variety of matters including general corporate, intellectual property, compliance matters and more, as needs arise
- Stay ahead of applicable laws, regulations, trends, and industry-specific guidance
- Execute other projects as the need arises as part of a small legal team
What You Bring:
Experience and Credentials:
- Juris Doctor (JD) from ABA-accredited law school with the ability to practice in Massachusetts.
- Minimum 5-6 years of legal experience, ideally including both in-house experience and law firm training
- Knowledge of the operations of a pharmaceutical or biotech company is a plus
Skills and Attributes:
- Strong negotiation abilities and business acumen.
- Deep contracting experience in the pharmaceutical space, particularly with clinical trial agreements, research collaborations, and strategic transactions
- Familiarity with intellectual property concerns within strategic agreements is ideal
- Strong drafting and analytical skills
- Strong organizational skills and attention to detail with a proven ability to handle multiple tasks efficiently and effectively
- Ability to manage multiple concurrent objectives, projects, groups, or activities, making effective judgments as to prioritizing and time allocation
- Collaborative, flexible, positive and pragmatic work style with excellent written and verbal communication skills
- Ability to thrive in a collaborative team setting and a desire to be innovative in rapidly evolving and fast-paced corporate environment
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
What We Do
Tango Therapeutics is a biotechnology company discovering and developing novel medicines targeting cancer vulnerabilities to deliver transformational new therapies for patients.
Tango was launched in 2017 with a $55 million Series A investment from Third Rock Ventures. The company has established a robust product engine that leverages advances in DNA sequencing and CRISPR-based target discovery to generate breakthrough medicines that have the potential to provide deeper, more sustained benefit than today’s targeted therapies, and extend the benefit of available immuno-oncology agents.
Tango Therapeutics is focused on three areas of drug development, each in well-defined patient populations currently lacking effective treatment options, and each with hallmarks of cancer that have not been targeted yet. These include: loss of tumor suppressor gene function; multiple oncogenic drivers; and immune evasion.
What fuels each of Tango’s programs is an increasingly sophisticated ability to utilize synthetic lethality - the interaction between two genes that causes cell death when both are inactivated. In cancer cells, one of these genes is inactivated by mutation; the other will be inactivated by a drug. This approach leaves normal cells largely unaffected, with the potential to greatly enhance anti-tumor efficacy and reduce associated toxicity.
Tango’s success will be driven by its depth of understanding of the genetic subtypes of cancer, and corresponding insights into novel drug targets and combinations uniquely relevant to each subtype. By shaping discovery efforts in this way, Tango has the potential to reach the clinic quickly, and with a clear plan for identifying the patients most likely to benefit from each new treatment, an approach that could increase both speed and probability of success in translating novel target discoveries into transformational new medicines for patients.

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