Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
We are seeking a highly motivated Research Associate with a focus on Drug Metabolism and Pharmacokinetics (DMPK) to join our team. The ideal candidate will contribute to our efforts in pharmacokinetics screening, plasma protein binding, and microsomal assays.
This role offers an exciting opportunity to work in a collaborative and fast-paced environment, supporting the development of cutting-edge therapies for cardiovascular and skeletal muscle disorders.
Responsibilities:
Bioanalysis: plasma and tissue processing/analysis to determine the drug concentration using the Sciex LC/MS-MS.
Plasma Protein Binding Studies: Conduct experiments to determine the binding affinity of compounds to plasma proteins using Sciex LC/MS-MS
Microsomal Assays: Perform microsomal stability studies to assess the metabolic stability and run the assay using the Sciex LC/MS-MS
Data Analysis and Interpretation: Analyze experimental data using appropriate software (WNL) and statistical methods and provide clear and concise summaries of findings to support decision-making.
Documentation and Reporting: Maintain detailed records of experimental procedures, results, and observations in laboratory notebooks and electronic databases. Prepare technical reports and presentations for internal meetings and regulatory submissions.
Collaboration: Collaborate effectively with cross-functional teams, including medicinal
chemistry, pharmacology, and toxicology, to support drug discovery and development projects.
Lab Maintenance: Ensure proper maintenance and organization of laboratory equipment, reagents, and supplies. Adhere to safety protocols and maintain a clean and safe working environment.
Qualifications:
Bachelor's with 3 to 5 years of experience or Master's degree in Pharmaceutical Sciences, Chemistry, Biochemistry, or a related field with 2 to 4 years.
Hands-on experience with DMPK assays, including screening, plasma protein binding, and microsomal assays are preferred but not required.
Proven analytical and problem-solving skills, with the ability to critically evaluate and interpret experimental data.
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Pay Range:
In the U.S., the hiring pay range for fully qualified candidates is $54.30-$63.35 per hour. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.
Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.
Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.
Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.
Here are some ways to check for authenticity:
We do not conduct job interviews through non-standard text messaging applications
We will never request personal information such as banking details until after an official offer has been accepted and verified
We will never request that you purchase equipment or other items when interviewing or hiring
If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at [email protected]
Please visit our website at: www.cytokinetics.com
Cytokinetics is an Equal Opportunity Employer
Skills Required
- Bachelor's with 3 to 5 years of experience or Master's degree with 2 to 4 years in Pharmaceutical Sciences, Chemistry, Biochemistry, or related field
- Hands-on experience with DMPK assays preferred
- Proven analytical and problem-solving skills
What We Do
Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised and/or declining. As a leader in muscle biology and the mechanics of muscle performance, we are developing small molecule drug candidates specifically engineered to impact muscle function and contractility. Proud to be a San Francisco Business Times Best Place to Work in 2021 and 2022, a Great Place to Work-Certified company in 2022 and a part of Fortune's Best Workplaces in the Bay Area in 2022 and Fortune's Best Workplaces in BioPharma in 2022.
