Jobs at Cytokinetics

Scientist I will design and synthesize novel small molecules for cardiovascular and neuromuscular drug discovery programs. Responsibilities include compound design, organic synthesis, chromatographic purification, compound characterization, multi-parameter optimization, computational modeling with tools such as MOE, and interpretation of biology and DMPK data. The role contributes to cross-functional project teams, documents experiments in an electronic lab notebook, and communicates research progress and findings.

Lead statistical support for clinical development, including protocol design, statistical analysis plans, clinical trial analyses, regulatory submissions, and interpretation of complex biomedical data. Collaborate cross-functionally to guide clinical strategy, decision-making, and regulatory interactions. Apply advanced statistical, machine learning, and AI methods to clinical and observational datasets while contributing to innovation and best practices.

Leads talent acquisition strategy and full-cycle recruiting across Europe for multiple business functions. Partners with senior leaders and HR on workforce planning, talent market insights, sourcing, pipelines, and hiring outcomes. Oversees recruiting agencies and contract recruiters, strengthens employer branding and university partnerships, and improves recruiting processes, systems, reporting, governance, and candidate experience. Ensures compliance with employment regulations and GDPR while coaching stakeholders and aligning European recruiting operations with global teams.

Lead HCP personal promotion marketing strategy and execution for cardiovascular therapies. Develop segmentation, positioning, messaging, promotional programs, and customer engagement initiatives while supporting launch readiness and brand growth. Partner with sales, medical affairs, market access, regulatory, legal, analytics, and omnichannel teams. Use market insights, competitive intelligence, and performance analytics to optimize commercial strategy, ensure compliance, and influence cross-functional execution.

Supports the CEO as a trusted administrative and strategic partner by managing complex calendars, executive and Board meetings, global travel, expenses, communications, confidential documents, stakeholder relationships, and special projects. The role requires exceptional discretion, autonomy, judgment, organization, business acumen, and responsiveness while coordinating with senior leaders, Board members, investors, partners, and other external stakeholders.

Leads marketing strategy and execution for cardiovascular therapies across Spain and Portugal. Responsibilities include brand positioning, launch planning, omnichannel engagement, market research, congresses, agency management, budgeting, performance monitoring, compliance, and cross-functional collaboration with Medical Affairs, Regulatory, Market Access, Sales, and global marketing teams.

Leads commercial strategy and execution across Spain and Portugal, including sales, marketing, stakeholder engagement, launch readiness, market access collaboration, team leadership, campaign oversight, compliance, P&L ownership, forecasting, and business planning. The role requires extensive Spanish pharmaceutical or biotech experience, specialty therapy launch success, healthcare-system expertise, and the ability to lead high-performing cross-functional teams.

Field-based Key Account Manager responsible for executing commercial strategy for aficamten in France: build customer targets and sales plans, engage HCPs/KOLs/centers, achieve sales targets, manage CRM and pharmacovigilance reporting, analyze territory and competitors, run high-value projects, and ensure compliance with legal and company regulations while collaborating with internal teams.

Serves as the strategic finance partner to Commercial functions, leading budgets, forecasts, long-range planning, operating expense and headcount management. Performs variance analysis, financial modeling, investment trade-off evaluation, launch and growth decision support, executive reporting, and board-level analysis. Builds scalable planning infrastructure, dashboards, and repeatable forecasting processes while advising senior leaders on financial risks, opportunities, and resource allocation.

Lead sourcing and supplier relationship management for CMOs, labs and critical suppliers across development through commercialization. Drive supplier selection, RFIs/RFPs, contract negotiations, performance monitoring, risk mitigation, audits, and cross-functional collaboration with CMC, Technical Operations, Procurement, Legal, Quality, and global teams.

Lead statistical genetics analyses (GWAS, fine-mapping, Mendelian randomization) and multi-omics integration to identify and prioritize genetic targets for cardiovascular and muscle diseases. Develop bioinformatics pipelines, manage large-scale genomic and clinical datasets, design AI/ML phenotyping methods, collaborate with biologists and clinicians, and communicate findings in publications and regulatory documents.

Lead statistician providing statistical leadership for clinical development and study design, SAPs, DMC coordination, regulatory submissions, exploratory analyses integrating multimodal data, mentoring staff, and advancing AI/ML-enabled insights across clinical programs.

Provide high-level, confidential administrative and operational support to the CFO and CFO organization, managing complex calendars, Board and audit materials, travel, meetings, executive communications, and special projects while handling sensitive financial and corporate information with discretion.

Serves as the strategic finance partner to Commercial leadership, leading budgets, forecasts, long-range planning, operating expense and headcount management. Performs variance analysis, evaluates commercial investments and launch decisions, develops financial models and business cases, and advises executives on risks, opportunities, and resource allocation. Builds scalable planning infrastructure, dashboards, and forecasting processes while preparing executive and Board-level analyses and presentations.

Leads enterprise strategy, business development analytics, drug revenue forecasting, valuation modeling, strategic planning, executive and board analyses, and the company’s AI initiative. Builds commercial forecasts from epidemiology, pricing, diagnosis, treatment, and uptake assumptions; develops rNPV, DCF, scenario, sensitivity, and transaction models; supports portfolio decisions and deal evaluations; coordinates AI governance and adoption; and delivers decision-ready recommendations to senior leadership and the Board.

Conduct preformulation assessments and develop formulations for poorly water-soluble small molecules supporting preclinical PK, pharmacology, and toxicology studies. Lead solid-form screening, solubility and stability testing, dissolution studies, and HPLC/UPLC method development. Manage laboratory timelines and contract research organizations, support candidate selection and first-in-human documentation, and author technical reports for CMC and regulatory use. Collaborate with cross-functional discovery, CMC, biology, chemistry, and pharmacokinetics teams.

Lead pricing governance, contracting, and market access analytics for GVAD. Develop deal modeling, performance dashboards, channel and distribution analyses, and actionable insights to inform contracting, revenue/rebate forecasts, and cross-functional decision-making.

Lead QA oversight for drug substance and drug product manufacturing and testing performed by CMOs/CTLs. Manage a QA team, approve batch records and GMP documents, oversee investigations/CAPAs, support inspections and audits, drive technology transfers, process validation, supplier oversight, and continuous improvement to ensure global regulatory compliance and product quality.

The Senior Manager, Quality Compliance leads quality compliance activities, overseeing product complaint handling, regulatory inspections, and quality processes while collaborating with cross-functional teams.

The Director of Operational Excellence will lead process improvement initiatives and enhance operational efficiency in Supply Chain and Manufacturing, ensuring high-quality medicine delivery. This role requires collaboration with stakeholders and expertise in Lean methodologies.