Jobs at Cytokinetics

Leads clinical and postmarketing pharmacovigilance operations, including ICSR review, case assessment, regulatory reporting, safety-data reconciliation, REMS support, vendor oversight, quality management, and inspection readiness. Develops scalable PV procedures, manages safety database activities, investigates deviations and CAPAs, and drives process improvements. Serves as a senior subject-matter expert while partnering with Drug Safety, Regulatory Affairs, Quality, Clinical Development, Medical Affairs, IT, and external vendors.

Provides legal support to European affiliates, focusing on drafting, negotiating, and managing commercial agreements. Advises business partners on contracting, distribution channels, competition law, privacy, GDPR, compliance, and legal risk across European jurisdictions. Supports the Irish entity on company secretarial and regulatory matters, collaborates with cross-functional teams, maintains EU-specific contract templates and playbooks, and contributes to AI-enabled contract management improvements.

Provides senior strategic legal counsel on corporate and commercial matters, including business development, licensing, technology acquisitions, contract negotiation, legal risk assessment, and cross-functional initiatives. Leads or supports legal technology and AI implementation, manages outside counsel and budgets, and advises business leaders on practical legal solutions. Requires substantial biotechnology, pharmaceutical, healthcare, in-house, or specialized law firm experience.

Leads pharmaceutical GDP Quality operations, Responsible Person duties, and WDA compliance for outsourced distribution activities. Oversees third-party logistics providers, distributors, wholesalers, supplier qualification, Quality Agreements, audits, CAPAs, deviations, recalls, temperature-controlled distribution, and inspection readiness. Establishes and improves the GDP quality system, maintains regulatory compliance across EU and global markets, and provides independent quality oversight within a virtual pharmaceutical organization.

Manages and improves GxP training programs, including curricula, assignments, learning materials, training systems, metrics, and inspection readiness. Develops instructor-led, virtual, and eLearning content; administers Veeva Vault Training; collaborates with Quality, IT, Document Control, and business stakeholders; supports audits and regulatory inspections; and ensures compliance with FDA, EMA, ICH, and other GxP requirements.

Leads European commercial sales training and capability development for a biopharmaceutical company. Responsibilities include designing competency frameworks, onboarding, sales curricula, launch-readiness programs, digital engagement training, field coaching, and just-in-time resources. The role oversees European training activities, measures effectiveness and ROI, manages budgets, and collaborates with sales, marketing, medical, regulatory, compliance, market access, HR, and country leadership. Regular travel across European markets is required for field coaching and training delivery.

Leads the company’s pharmaceutical Quality Systems organization, overseeing QMS, document control, GxP training, inspection readiness, compliance, continuous improvement, metrics, and eQMS enhancements. Manages Quality professionals, establishes strategic roadmaps and budgets, ensures alignment with FDA, EMA, ICH, and cGMP requirements, and serves as the QMS business process owner.

Conduct in vivo and in vitro cardiovascular research supporting preclinical drug development. Responsibilities include rodent handling and dosing, tissue collection, primary cell isolation, ex vivo organ experiments, molecular and biochemical assays, iPSC-derived cardiomyocyte and engineered heart tissue studies, and assay development. The role requires independent experimental design, troubleshooting, data interpretation, project ownership, and collaboration across scientific disciplines.

Scientist I will design and synthesize novel small molecules for cardiovascular and neuromuscular drug discovery programs. Responsibilities include compound design, organic synthesis, chromatographic purification, compound characterization, multi-parameter optimization, computational modeling with tools such as MOE, and interpretation of biology and DMPK data. The role contributes to cross-functional project teams, documents experiments in an electronic lab notebook, and communicates research progress and findings.

Leads talent acquisition strategy and full-cycle recruiting across Europe for multiple business functions. Partners with senior leaders and HR on workforce planning, talent market insights, sourcing, pipelines, and hiring outcomes. Oversees recruiting agencies and contract recruiters, strengthens employer branding and university partnerships, and improves recruiting processes, systems, reporting, governance, and candidate experience. Ensures compliance with employment regulations and GDPR while coaching stakeholders and aligning European recruiting operations with global teams.

Lead HCP personal promotion marketing strategy and execution for cardiovascular therapies. Develop segmentation, positioning, messaging, promotional programs, and customer engagement initiatives while supporting launch readiness and brand growth. Partner with sales, medical affairs, market access, regulatory, legal, analytics, and omnichannel teams. Use market insights, competitive intelligence, and performance analytics to optimize commercial strategy, ensure compliance, and influence cross-functional execution.

Supports the CEO as a trusted administrative and strategic partner by managing complex calendars, executive and Board meetings, global travel, expenses, communications, confidential documents, stakeholder relationships, and special projects. The role requires exceptional discretion, autonomy, judgment, organization, business acumen, and responsiveness while coordinating with senior leaders, Board members, investors, partners, and other external stakeholders.

Leads commercial strategy and execution across Spain and Portugal, including sales, marketing, stakeholder engagement, launch readiness, market access collaboration, team leadership, campaign oversight, compliance, P&L ownership, forecasting, and business planning. The role requires extensive Spanish pharmaceutical or biotech experience, specialty therapy launch success, healthcare-system expertise, and the ability to lead high-performing cross-functional teams.

Field-based Key Account Manager responsible for executing commercial strategy for aficamten in France: build customer targets and sales plans, engage HCPs/KOLs/centers, achieve sales targets, manage CRM and pharmacovigilance reporting, analyze territory and competitors, run high-value projects, and ensure compliance with legal and company regulations while collaborating with internal teams.

Serves as the strategic finance partner to Commercial functions, leading budgets, forecasts, long-range planning, operating expense and headcount management. Performs variance analysis, financial modeling, investment trade-off evaluation, launch and growth decision support, executive reporting, and board-level analysis. Builds scalable planning infrastructure, dashboards, and repeatable forecasting processes while advising senior leaders on financial risks, opportunities, and resource allocation.

Lead statistical genetics analyses (GWAS, fine-mapping, Mendelian randomization) and multi-omics integration to identify and prioritize genetic targets for cardiovascular and muscle diseases. Develop bioinformatics pipelines, manage large-scale genomic and clinical datasets, design AI/ML phenotyping methods, collaborate with biologists and clinicians, and communicate findings in publications and regulatory documents.

Provide high-level, confidential administrative and operational support to the CFO and CFO organization, managing complex calendars, Board and audit materials, travel, meetings, executive communications, and special projects while handling sensitive financial and corporate information with discretion.

Serves as the strategic finance partner to Commercial leadership, leading budgets, forecasts, long-range planning, operating expense and headcount management. Performs variance analysis, evaluates commercial investments and launch decisions, develops financial models and business cases, and advises executives on risks, opportunities, and resource allocation. Builds scalable planning infrastructure, dashboards, and forecasting processes while preparing executive and Board-level analyses and presentations.

Leads enterprise strategy, business development analytics, drug revenue forecasting, valuation modeling, strategic planning, executive and board analyses, and the company’s AI initiative. Builds commercial forecasts from epidemiology, pricing, diagnosis, treatment, and uptake assumptions; develops rNPV, DCF, scenario, sensitivity, and transaction models; supports portfolio decisions and deal evaluations; coordinates AI governance and adoption; and delivers decision-ready recommendations to senior leadership and the Board.

Conduct preformulation assessments and develop formulations for poorly water-soluble small molecules supporting preclinical PK, pharmacology, and toxicology studies. Lead solid-form screening, solubility and stability testing, dissolution studies, and HPLC/UPLC method development. Manage laboratory timelines and contract research organizations, support candidate selection and first-in-human documentation, and author technical reports for CMC and regulatory use. Collaborate with cross-functional discovery, CMC, biology, chemistry, and pharmacokinetics teams.