At Renasant Bio, we are driven by a singular goal: to change what’s possible for patients with kidney disease. ADPKD remains one of the most challenging areas in medicine, and we believe it requires bold thinking, rigorous science, and a team committed to doing things differently.
We’re looking for individuals who bring both scientific rigor and creativity to hard problems, and who believe great work is built through respectful, direct collaboration. You communicate with honesty and transparency, adapt quickly as priorities evolve, and hold yourself—and others—to a high standard. Above all, you operate with urgency and purpose, grounded in the knowledge that patients are waiting.We are seeking a highly motivated Contract Research Associate / Senior Research Associate with strong hands-on expertise in mammalian tissue culture and cell line generation to support our Early Discovery Biology team.
This is a bench-focused role critical to enabling our discovery pipeline through the generation, maintenance, and characterization of robust cell models. The ideal candidate is highly organized, technically strong in tissue culture, and comfortable working in a fast-moving startup environment with evolving priorities.
Key Responsibilities
- Independently perform mammalian tissue culture, including cell maintenance, expansion, passaging, cryopreservation, and cell banking
- Generate and characterize stable mammalian cell lines, including pooled and clonal populations
- Execute cell engineering workflows including transfection/transduction, antibiotic selection, and clone expansion
- Support cell-based assays and experimental workflows across discovery programs
- Monitor cell health, troubleshoot culture issues, and ensure consistent high-quality cell supply
- Maintain accurate experimental records and support protocol optimization
- Manage tissue culture reagents, inventory, and general lab organization
- Collaborate closely with scientists across biology to support project timelines and deliverables
Requirements
- BS or MS in Cell Biology, Molecular Biology, Biotechnology, or related field
- 3+ years (RA) or 5+ years (Senior RA) of hands-on mammalian cell culture experience
- Demonstrated expertise in aseptic technique and mammalian cell line maintenance
- Experience generating stable cell lines (transfection/transduction, selection, clonal expansion)
- Experience with cell counting, viability assessment, and cryopreservation • Strong troubleshooting, organizational, and communication skills
- Ability to work independently in a fast-paced team environment
- Biotech industry experience
- Familiarity with molecular biology techniques (RNA prep, protein prep)
- Experience with protein characterization methods (Western blot, immunostaining, flow cytometry)
Preferred
Please note that we do not accept unsolicited resumes from recruitment agencies and external recruiters. No fees will be paid for such submissions.
Skills Required
- BS or MS in Cell Biology, Molecular Biology, Biotechnology, or related field
- 3+ years hands-on mammalian cell culture experience
- Demonstrated expertise in aseptic technique and mammalian cell line maintenance
- Experience generating stable cell lines (transfection/transduction, selection, clonal expansion)
- Strong troubleshooting, organizational, and communication skills
What We Do
5AM was founded in 2002 and pursues investments in advanced life science innovations, and seeks to be diversified across the biopharmaceutical therapeutics, and platform technologies. Within each sector, 5AM invests across multiple therapeutic areas and modalities and evaluates opportunities based on innovative platform technologies, corporate spin-offs and products with shorter development cycles. Content 5AM shares on this platform is not, and may not be relied on, in any manner, as legal, tax, investment, accounting or other advice or as an offer to sell or a solicitation of an offer to buy an interest in any private fund, special purpose or other investment vehicle sponsored by 5AM Ventures. Content 5AM shares on this platform is not an investment recommendation. For a full list of all 5AM portfolio companies, please visit: https://5amventures.com/portfolio/
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