The Problem
Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.
What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.
We are developing all of it. The care, the science, the technology.
Who We Are
Amae Health is a Series B, venture-backed Public Benefit Corporation delivering specialty outpatient care for people with severe mental illness through high-acuity, in-person clinics nationwide.
Our integrated model brings psychiatry, therapy, primary care, dietitians, and community support together under one roof. Leading health systems—including NewYork-Presbyterian, Cedars-Sinai, Mass General Brigham, Novant Health, and CommonSpirit—partner with us to expand this level of care.
Alongside care delivery, we are building the science and technology the field has long lacked—proprietary clinical protocols, novel measurement, and an AI-driven data platform designed for severe mental illness.
The impact: fewer hospitalizations, greater stability, and more people living meaningful lives in their communities.
The Team
We are clinicians, operators, technologists, and scientists who chose Amae because the problem is hard and the stakes are real. We are not interested in incremental improvements to a broken system—we are redefining it.
Our teams work cross-functionally because the work demands it. The psychiatrist informs the product roadmap. Engineers understand the clinical complexity their technology must solve. Researchers sit alongside the operators running the clinics their work measures. Every function—finance, product, people, growth, technology—exists to serve one goal: better outcomes for the people we care for.
The Role
Reporting to the Co-Founder & CEO, this role will facilitate both internal and external work streams, supporting various efforts including managing the office of the CEO, and enabling successful execution of strategic programs. Primary functions include special projects, communications, fundraising, hiring, administration, and C-Suite planning. Highly cross-functional, the Chief of Staff will navigate high-priority, sensitive business initiatives in a collaborative and team focused manner.
What You’ll Do
- Act as an in-house consultant and strategic advisor to the executive and senior leadership team based on priorities and vision of the CEO
- Lead the process for development of the long-term strategy and annual strategic plan in collaboration with the C-Suite
- Develop/maintain KPI Dashboard and high-level performance metrics
- Provide insights and develop strategic communications for the CEO
- In partnership with the executive team, execute and manage strategic projects and tasks, and operate as a self-starter
- Produce and edit persuasive business communications
- Establish a centralized insights, analytics process to power decisions and strategy
What You'll Have
- 2+ years professional experience in consulting; investment banking; investing (venture capital or private equity); or within a start-up organization
- Strategic and flexible approach to business problem solving
- Intellectually curious and can serve as an effective thought partner to all; bringing creativity, an analytical mind, and high intellectual horsepower
- You’re comfortable using tools like ChatGPT/Claude to accelerate research, writing, analysis, and ops workflows (and you know when not to rely on them)
- High attention to detail, even under urgent or high-pressure circumstances
- Experience managing multiple projects in a highly dynamic and fluid environment
- High-wattage energy that's infectious across teams -- the kind of person who raises the tempo of every room they walk into
- Passion and interest for Amae’s mission
- This is 100% in person full-time role based in our San Francisco office in the Cow Hollow / Marina
What We’re Building
Most healthcare companies ask you to optimize an existing system. We’re building one that has never existed.
- A national care model designed for the highest-acuity patients in behavioral health.
- Precision medicine for severe mental illness, using multimodal clinical, behavioral, and social data to personalize treatment.
- A clinical operating system that integrates longitudinal data, real-time patient signals, and purpose-built tools into a single decision layer.
- New science and measurement frameworks to define what real outcomes look like in SMI—stability, functional improvement, and hospitalizations avoided.
- A health-system partnership model proving coordinated SMI care can work at scale.
If you want to maintain the status quo, this isn’t the place. If you want to build what doesn’t exist yet—and change how an entire population receives care—keep reading.
Compensation & Benefits
Compensation includes a base salary of $125,000 - $185,000 (based on experience) plus equity ownership, giving you a meaningful stake in Amae's growth. Total compensation includes comprehensive medical/dental/vision, unlimited PTO, parental leave, and programs built around employee well-being. We’ll share specifics during the interview process.
Amae Health is building the care platform, the precision medicine, and the frontier science that severe mental illness has never had. If you want to be part of creating something this hard and this important, something that has never been done, we’d like to talk.
What We Value
We center care in all we do. Empathy is not a brand value. It’s how we make clinical decisions, build products, and treat each other.
We challenge convention. The existing system is the problem. We question it, we test alternatives, and we move with urgency when something works.
We take the work seriously, not ourselves. High standards and humanity are not in tension. We hold a hard bar for quality while leaving room for humor and levity.
Your job isn’t done until the job is done. We close gaps, we follow through, and we don’t hide behind titles or org charts.
We win together and fail together. We own outcomes as a team. We learn fast. We don’t do blame.
We hustle with humility. Speed matters. So does integrity. We assume best intent and stay grounded in the mission.
Skills Required
- 2+ years professional experience in consulting, investment banking, investing (VC/PE), or at a startup
- Strategic and flexible approach to business problem solving
- Intellectually curious and effective thought partner with strong analytical skills
- Comfortable using tools like ChatGPT or Claude to accelerate research, writing, analysis, and ops workflows
- High attention to detail under urgent or high-pressure circumstances
- Experience managing multiple projects in a highly dynamic and fluid environment
- Strong written communication skills to produce and edit persuasive business communications
- High-energy, team-oriented personality who raises the tempo of teams
- Passion and interest for Amae's mission (severe mental illness care)
- This is a full-time, 100% in-person role based in the San Francisco Cow Hollow / Marina office
What We Do
Amae Health is a Public Benefit Corporation providing specialized, psychiatry-led outpatient care for individuals with severe mental illness (SMI), such as schizophrenia and bipolar disorder. They operate in-person clinics that integrate psychiatry, therapy, primary care, and social support, utilizing a data-driven precision medicine platform and AI-powered tools to improve patient outcomes and redefine the care experience.
