The Reagent Discovery group in Discovery Tech Futures, R&D, is looking for a motivated Automated Antibody Engineering Scientist to join a team focused on developing high-throughput antibody workflows for the next generation of IDEXX diagnostics. The successful candidate will employ a broad range of molecular biology and biochemistry techniques — from gene design and cloning through antibody generation to provide validated reagents for downstream immunoassay development. The ideal candidate will thrive in a dynamic, multidisciplinary, and collaborative environment.
At IDEXX, the ability to rapidly develop high-quality antibody reagents is foundational to advancing pet health diagnostics. The Reagent Discovery team is the critical bridge between biomarker discovery and immunoassay development — and this role sits at the center of that pipeline. As a Scientist II, you will drive the molecular biology and antibody generation workflows that move novel biomarkers from target sequence to validated reagent, directly enabling new diagnostic tools for the veterinarians and pet owners we serve.
You will need direct experience with molecular biology techniques, including primer design, gene synthesis, cloning strategies, and recombinant construct development for antibody expression.
You have designed and executed workflows for antibody generation using recombinant antibody expression, display technologies, or a combination of platforms.
You are comfortable working across the full bench workflow — from sequence analysis and construct design through transfection, expression, and basic protein characterization.
You have worked cross-functionally with discovery and assay development teams, communicating experimental data clearly and aligning with stakeholders on project timelines.
You are organized and detail-oriented, with the ability to advance multiple concurrent projects in a fast-paced environment.
Design and execute molecular biology workflows for antigen and antibody construct development, including primer design, PCR-based cloning, site-directed mutagenesis, and sequence verification.
Develop and optimize recombinant expression constructs using mammalian, insect, or bacterial systems to support high-throughput antigen production.
Devise and execute antibody generation workflows, including platform selection, immunization or display screening, and hit confirmation.
Perform protein and antibody characterization utilizing standard biochemical techniques including SDS-PAGE, Western blot, ELISA, BLI, and analytical SEC.
Develop and maintain automated liquid handling protocols to increase throughput and reproducibility across molecular biology and screening workflows.
Collaborate with LC/MS and genomics teams to evaluate incoming biomarker targets and establish feasible antigen design and production strategies.
Partner with downstream immunoassay development teams to communicate reagent performance data, define acceptance criteria, and meet delivery milestones.
Generate clear, concise presentations and communicate progress updates to cross-functional audiences.
Leverage published literature to identify novel molecular biology, antibody generation, and expression technologies applicable to the Reagent Discovery pipeline.
Document experiments and maintain accurate electronic records. Adheres to appropriate safety procedures and regulatory requirements.
A degree in Molecular Biology, Biochemistry, Immunology, or a related discipline Candidates should possess a Bachelor’s with 5-7 years’ of relevant laboratory experience, Master's with 3-5 years’ experience of relevant laboratory experience.
Strong hands-on experience with molecular biology techniques including primer design, PCR, restriction enzyme cloning, Gibson assembly, site-directed mutagenesis, and sequence analysis is a must.
Experience with recombinant protein or antibody expression in mammalian, insect, or bacterial systems is a must.
Familiarity with standard protein characterization techniques (e.g., SDS-PAGE, analytical SEC, Western blot, ELISA).
Familiarity with laboratory automation platforms (e.g., Hamilton, Tecan, Biomek, or similar liquid handling systems).
Experience in protein purification utilizing AKTA FPLC or similar instruments is a plus.
Experience in antibody discovery platforms such as hybridoma technology, phage display, or single B-cell cloning is a plus.
Background in immunoassay development or in vitro diagnostics is a plus.
Working knowledge of binding assay technologies such as BLI or SPR is a plus.
Ability to work independently and collaboratively toward a unifying set of goals.
Strong analytical, problem-solving, and communication skills are a must.
Organizational skills and ability to plan and prioritize work across multiple projects are a must.
Takes initiative and is accountable; detail-oriented and adaptable to shifting priorities.
Salary range starting at $90,000 based on experience
Opportunity for annual cash bonus
Health / Dental / Vision Benefits Day-One
5% matching 401k
Additional benefits including but not limited to financial support, pet insurance, mental health resources, volunteer paid days off, employee stock program, foundation donation matching, and much more
If you’re looking for a role that’ll challenge you, offer a variety of work and learning, while helping an amazing industry, we’d love to hear from you!
Why IDEXX:
We’re proud of the work we do, because our work matters. An innovation leader in every industry we serve since 1983, our team members help pet owners worldwide keep their companion animals healthy and happy, ensure safe drinking water for billions, and help farmers protect livestock and poultry from disease.
We have customers in over 175 countries and a collaborative global workforce. Our culture embraces challenges and encourages learning and discovery. At IDEXX, you’ll be supported by competitive compensation, incentives, and benefits while enjoying purposeful work that drives improvement.
If meaningful work and a sense of purpose are at the top of your list, you’ll find it here. Let’s pursue what matters together.
About the job location:If you’re thinking about relocating for this role, here are a few things to know about living in Maine (often called “Vacationland”). The Westbrook, ME area provides great access to active downtown areas and the outdoors, with the coast and numerous mountains and hiking trails nearby. You’ll also find a number of large companies like ours in the area, creating a vibrant work culture.
You can learn more on the Portland tourism website: https://www.visitportland.com/visit/resources/moving-to-maine/
IDEXX values a diverse workforce and workplace and strongly encourages women, people of color, LGBTQ+ individuals, people with disabilities, members of ethnic minorities, foreign-born residents, and veterans to apply.
IDEXX is an equal opportunity employer. Applicants will not be discriminated against because of race, color, creed, sex, sexual orientation, gender identity or expression, age, religion, national origin, citizenship status, disability, ancestry, marital status, veteran status, medical condition, or any protected category prohibited by local, state, or federal laws.
While we appreciate our staffing partners, we are unable to accept unsolicited agency resumes.
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Skills Required
- Bachelor's degree in Molecular Biology, Biochemistry, Immunology, or related field with 5-7 years' lab experience, or Master's with 3-5 years' experience
- Hands-on experience with primer design, PCR, restriction enzyme cloning, Gibson assembly, site-directed mutagenesis, and sequence analysis
- Experience with recombinant protein or antibody expression in mammalian, insect, or bacterial systems
- Familiarity with protein characterization techniques including SDS-PAGE, analytical SEC, Western blot, and ELISA
- Familiarity with laboratory automation/liquid handling platforms (e.g., Hamilton, Tecan, Biomek) and development of automated protocols
- Ability to document experiments, maintain accurate electronic records, and adhere to safety and regulatory requirements
- Experience with AKTA FPLC or similar protein purification instruments
- Experience with antibody discovery platforms such as hybridoma technology, phage display, or single B-cell cloning
- Background in immunoassay development or in vitro diagnostics
- Working knowledge of binding assay technologies such as BLI or SPR
- Strong analytical, problem-solving, communication, organizational skills, and ability to manage multiple projects
IDEXX Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about IDEXX and has not been reviewed or approved by IDEXX.
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Healthcare Strength — Health coverage is described as comprehensive with day-one eligibility and added programs for mental health and musculoskeletal care. Feedback suggests insurance quality is strong, with multiple plan options and supportive wellness services.
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Retirement Support — Retirement savings support is highlighted through a clear 401(k) match that begins after an initial waiting period. Feedback suggests this materially strengthens total compensation beyond base pay.
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Leave & Time Off Breadth — Time-off programs are depicted as generous, including PTO, paid holidays, and volunteer days. Parental leave and adoption assistance add to the breadth of paid leave options.
IDEXX Insights
What We Do
10,000 people, one global focus - enhancing the health and well-being of pets, people, and livestock. We are passionate about what we do at IDEXX – and why wouldn’t we be? When you’re working to raise the standard of care for pets, make drinking water safe for billions and keep our livestock population around the globe healthy and free of disease, it’s no wonder that what we do each day is more than just a job. There’s an energy across IDEXX that is contagious – where caring and committed people come together to make things better. IDEXX Laboratories, Inc. (NASDAQ: IDXX), a member of the S&P 500, is a leader in pet healthcare innovation, serving practicing veterinarians around the world with a broad range of diagnostic and information technology-based products and services. Headquartered in southern Maine, we conduct operations through more than 70 locations around the world and serve customers in over 175 countries. Our primary business focuses on pet health, a growing market around the world. Our products —in-clinic diagnostic tests and instrumentation, reference laboratory and telemedicine consultation services, and practice management software—enhance the ability of veterinarians to provide advanced medical care, improve staff efficiency and to build more economically successful practices. We also develop and manufacture diagnostic tests and information for the global production animal industry, including poultry and livestock, as well as tests for the quality and safety of water and milk. Please visit our website, IDEXX.com/careers, for further information and to view all of our job opportunities.
