Company Overview:
Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.
Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.
Today, Strand has established multiple programmable mRNA platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a Phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.
Become the next standout single strand!
Job Summary:
Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a team with significant impact on Strand’s cell engineering programs. This opportunity will offer the employee the ability to work in a cross-functional environment and be a part of the future strategy of the company.
We are looking for a highly motivated and innovative candidate for the role of Associate Scientist II of NGS. This candidate will possess experience in high-throughput DNA and RNA sequencing workflows. This is a fantastic opportunity to make a significant impact as a scientifically motivated self-starter capable of independently conceiving, conducting, and critically analyzing their own work with minimal supervision.
Primary Responsibilities:
- Executing and supporting the development of Illumina NGS workflows, including library prep, sample QC, and sequencing.
- Executing and supporting the development of Oxford nanopore NGS workflows, including library prep, sample QC, and sequencing.
- Extracting DNA and RNA from diverse biological sources.
- Assisting with data analysis, summarizing results in study reports, maintaining clear records in an electronic lab notebook, and providing updates at team meetings.
Qualifications:
- B.S. or M.S. in Biological Sciences or related discipline.
- 2-4+ years of research experience in a biotechnology, pharmaceutical, and/or academic environment required.
- Experience with NGS library prep and Illumina instruments required.
- Experience with RNA and DNA extraction methods preferred.
- Experience with Oxford nanopore sequencing preferred.
- Experience using automation equipment preferred.
- Experience with cellular and molecular biology techniques such as mammalian cell culture, flow cytometry, and qPCR is a plus.
- Experience coding with python a plus.
Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals.
Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.
Job Type: Full-time
Salary: $82,000 - $88,000 annually plus bonus and equity incentives
Top Skills
What We Do
Strand was started by biological engineers working together at MIT. Building on the idea of creating smart therapies that are capable of making sophisticated decisions, they sought to apply the concept of the emerging field of mRNA therapeutics. This area was untapped by traditional synthetic biology, which led them to build their own mRNA “programming language,” creating the world’s first platform for mRNA smart therapies. Strand’s mRNA programming technology promises to make mRNA therapies safer and more effective by programming the location, timing, and intensity of therapeutic protein expression inside a patient’s body using mRNA-encoded logic circuits. These circuits can implement cell-type specific expression by sensing and classifying the unique miRNA expression signatures of cells, as well as controlling the dosage of protein expression by responding to exogenously administered small molecules.
