At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function:
Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:
Biotherapeutics R&DJob Category:
Scientific/TechnologyAll Job Posting Locations:
Spring House, Pennsylvania, United States of AmericaJob Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine
An internal pre-identified candidate for consideration has been identified. However, all applications will be considered.
We are searching for the best talent for an Associate Scientist I.
Purpose: This role will focus on CAR screening and lead selection (CSLS) to support the development of CAR-T cell therapies.
This position offers an exciting opportunity to contribute to the field of CAR-T cell therapy and work alongside a team of passionate scientists advancing cutting-edge treatments targeting hematological and solid tumors.
Key Responsibilities:
- Assist in the culture and expansion of primary T cells, as well as the generation of CAR-T cells via viral transduction techniques
- Support the development and optimization of high- and medium-throughput CAR-T cell manufacturing workflows
- Perform flow cytometry-based experiments for cellular characterization and analysis
- Perform Droplet Digital PCR (ddPCR) assays and analysis of vector copy numbers (VCN) of CAR T cells
- Operate, maintain, and troubleshoot basic automation systems utilized in cell therapy processes
- Identify and resolve technical challenges encountered during laboratory procedures to ensure smooth workflow
- Analyze experimental data using software tools such as GraphPad PRISM, FlowJo, and Microsoft Office Suite
- Maintain precise and comprehensive experimental records in electronic laboratory notebooks (ELNs) to ensure reproducibility and compliance
- Collaborate with cross-functional team members to refine protocols, enhance process efficiency, and achieve project milestones
- Strictly adhere to safety protocols, regulatory standards, and laboratory guidelines while performing experiments
Qualifications:
- Bachelor’s degree in Biology, Biotechnology, Biomedical Engineering, or a related field and at least 2 years of laboratory experience (industry experience is preferred).
- Or a Master’s Degree in Biology, Biotechnology, Biomedical Engineering or a related field with at least a year of laboratory experience.
- Hands-on experience with Pipetting (single and multi-channel pipettes), aseptic cell culture, cell banking, with a strong preference for experience working with primary immune cells.
- Experience with multicolor Flow Cytometry is required.
- Experience with ddPCR and VCN assays is highly preferred.
- Experience working in BSL2 and BSL2+ labs; familiarity with viral transduction techniques is highly desirable.
- Exposure to automation technologies used in laboratory workflows is preferred.
- Basic proficiency with data analysis tools and software, such as GraphPad PRISM, FlowJo, and Microsoft Office.
- Strong organizational abilities and attention to detail, with a demonstrated ability to maintain clear and accurate records.
- Effective communication and interpersonal skills to succeed in a collaborative team setting.
- Motivated, and ability to learn new techniques, perform multiple tasks simultaneously.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
- Availability to work on-site in Spring House, PA, during standard business hours.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([email protected]) or contact AskGS to be directed to your accommodation resource.
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Johnson & Johnson is the largest and most broadly based healthcare company in the world. We’re producing life-changing breakthroughs every day, and have been for the last 130 years.
The combination of new technologies and your expertise enables amazing things to happen. Teams from J&J’s consumer business are creating digital tools to help people track the health of their skin. Those working in medical devices are 3-D printing artificial joints personalized for each patient, while researchers in pharmaceuticals use AI to discover lifesaving drugs. Imagine what the rest of our team of 134,000 people at 260 companies in more than 60 countries across the world is accomplishing. We redefine what it means to be a big company in today’s world.
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