Sail Biomedicines is harnessing evolutionary and artificial intelligence to revolutionize programmable medicines. Sail’s platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is building a wealth of data, enabling unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.
Sail is seeking a highly motivated Associate Scientist to join our Separation Sciences team within Analytical Sciences. This role will contribute to the advancement of our proprietary lipid nanoparticle and eRNA platforms by developing analytical procedures based on state-of-the-art separation methodologies. The ideal candidate will thrive in a dynamic, goal-oriented environment and demonstrate strong technical expertise, attention to detail, and interdisciplinary communication skills.
- Develop and implement novel analytical methods for new product characterization, release, and stability testing.
- Design and execute analytical experiments to assess product quality attributes and characterize Sail’s development candidates.
- Deploy high-throughput methods to assess preclinical materials.
- Contribute to the transfer of analytical procedures to internal and external teams.
- Analyze samples, perform data analysis, and maintain timely experiment documentation including authoring SOPs.
- Present analytical findings at internal meetings.
- BS in Chemistry, Biochemistry, or related discipline with 6+ years of experience in biotechnology/pharmaceuticals (or MS with 4+ years of experience).
- Expertise in physicochemical and biophysical methodologies, with extensive hands-on experience developing HPLC-based analytical procedures in biopharmaceutical settings.
- Proficiency with Empower, OpenLabs, or similar analytical software.
- Experience maintaining laboratory notebooks and following SOPs.
- Highly organized team player with excellent oral and written communication skills.
- Self-starter, detail-oriented, capable of managing laboratory activities effectively.
- Demonstrated ability to engage productively with diverse scientific stakeholders.
- Experience with mass spectrometry analysis of lipids, nucleic acids, and/or recombinant proteins would be an asset.
What We Do
Senda Biosciences, Inc. is uniquely positioned to transform human health by harnessing millions of years of evolution to program targeted, potent and tunable medicines. Nature has provided the codes to program human cells – both within the cell (mRNA), and, remarkably, to the cell - using what surrounds it. The trillions of non-human cells in the human ecosystem have evolved natural nanoparticles that precisely shuttle biomolecules into human cells, providing the missing pieces to fully unlock programmable medicines. Senda’s proprietary platform includes the first-ever atlas of nature-derived programmable systems at the molecular level and across all kingdoms of life – accessing the entire code provided by nature required to program cells. With this platform, Senda is developing a new class of SendRNA™ medicines. The unique properties of these medicines create new frontiers for mRNA therapeutics and vaccines for infectious, genetic, autoimmune, and metabolic diseases and oncology indications – with further potential to transform the gene editing and protein-based therapy landscapes as well. Based in Cambridge, MA, Senda was founded by Flagship Pioneering.
