Associate Research Fellow, Analytical Development

ROLE SUMMARY
As an Associate Research Fellow in Chemical Process and Analytical Development (CPAD) you will provide technical leadership to a team of process and analytical chemists engaged in the development and characterization of processes for our growing Drug-Linker portfolio. You will drive product characterization and development of robust control strategies by leveraging state-of-the-art technologies in chromatography and spectrometry. You will spearhead the advancement of Pfizer's Oncology portfolio through personal laboratory effort as well as oversee external resources through technology transfer and campaign execution at Contract Development and Manufacturing Organizations (CDMO). You will serve as a technical and strategic leader for early and late-phase programs while mentoring junior staff members in a supportive and inclusive work environment. You will propose technical and strategic solutions to Management and represent analytical development in cross-functional teams requiring excellent communication skills. Finally, you will be expected to establish an external presence as technical leader in the field by authoring journal articles and presenting at leading external scientific meetings.
ROLE RESPONSIBILITIES

• Lead Analytical method development activities for multiple Drug-Linker programs in across all development phases, including supporting manufacturing process development, developing, validating and transferring analytical methods and designing stability studies.
• Contribute to and potentially lead multidisciplinary teams at the sub-function level, developing plans and managing resources for development projects.
• Collaborate with colleagues to identify appropriate analytical approaches, including use of computational predictive tools, modeling software and data visualization tools where appropriate.
• Evaluate new approaches, instrumentation or analytical technologies.
• Develop appropriate Drug-Linker analytical control strategies that align with program and regulatory expectations.
• Encourage effective collaboration with project team members, presenting data, critically reviewing results, and solving technical challenges during development.
• Support off-site analytical technology transfers, method validation, manufacturing support, and interactions with CDMO's.
• Author relevant sections of the quality modules of regulatory submissions.

QUALIFICATIONS

• PhD with at least 12+ years of experience in pharmaceutical development.
• Effective leadership skills and the ability to enhance collaboration within a cross-functional team.
• Exceptional written communication skills, including the ability to maintain a precise scientific notebook and draft clear, concise reports, publications, and related documents.
• Deep experience in a wide range of analytical methodologies such as High-Pressure Liquid Chromatography, Ultra High-Pressure Liquid Chromatography, Gas Chromatography, and Mass Spectrometry.
• Demonstrated expertise in troubleshooting instruments and navigating various software and information systems, including electronic lab notebooks, OpenLab, and Laboratory Information Management Systems (LIMS).
• Proven track record of effective people management skills, either through direct line supervision or leading project teams.
• Ability to work independently and make decisions in ambiguous situations.

PREFERRED QUALIFICATIONS

• Experience with Drug-Linkers for Antibody Drug Conjugates (ADCs) or other targeted mixed-modality therapeutics.
• Experience in mentoring scientific staff, both directly and in a matrix environment.
• Experience with technology transfer activities and CRO/CDMO resource management.
• Experienced in authoring regulatory documents such as Investigational New Drug application (IND's) and New Drug Applications (NDA's).
• Experience in preparative chromatography is a plus.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
This is a lab-based position which requires adherence to safe work practices and procedures such as dawning appropriate PPE and working with engineering controls such as isolators and laminar flow hoods.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Occasional domestic and international travel required; CMOs,Conferences, etc.
PHYSICAL/MENTAL REQUIREMENTS

• This is a lab-based position with extended sitting periods
• The successful candidate will be capable of independent problem solving and working with minimal direction under most circumstances. Applicants should demonstrate strongly collaborative behaviors. The successful candidate will also possess strong oral and written communication skills. Strong analytical and computer skills are required.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
This is a lab-based position which requires adherence to safe work practices and procedures such as dawning appropriate PPE and working with engineering controls such as isolators and laminar flow hoods.
Occasional travel required.
Relocation support available
Work Location Assignment: Full-time on premise
The annual base salary for this position ranges from $156,600.00 to $261,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development