Associate Director / Principal Research Scientist II, Precision Medicine Immunology

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Waltham, MA, USA
Hybrid
142K-269K Annually
Senior level
Healthtech • Pharmaceutical
The Role
Leads translational and biomarker strategy, execution, interpretation, and reporting for immunology clinical development programs. Oversees assay development, sample management, CRO coordination, data analysis, regulatory documentation, budgets, timelines, and publication strategies. Directs cross-functional teams and collaborates with Medical Affairs, Commercial, regulatory stakeholders, and external scientific experts. Applies immunology and precision medicine expertise to clinical trial programs, biomarker research, and development strategy.
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Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Precision Medicine Immunology group is seeking an experienced translational and biomarker scientist with expertise in immunology to lead the development, planning, execution, and interpretation of precision medicine activities supporting AbbVie’s immunology clinical development portfolio.
 

Key responsibilities include:

  • Translational and biomarker strategy: Lead the development and implementation of translational and biomarker strategies for one or more clinical programs, spanning early translational development, mature product life cycle planning, and back-translational research.
  • Biomarker execution and interpretation: Oversee the design, conduct, interpretation, and reporting of biomarker activities and data in alignment with development, regulatory, and commercial strategies.
  • Cross-functional leadership: Lead asset-specific translational projects and teams within a matrixed environment.
  • Operational coordination: Partner with the internal Operations group to coordinate sample management, assay validation at internal laboratories and external CROs, statement-of-work reviews, and data management.
  • Program planning and compliance: Collaborate with key stakeholders to incorporate translational budgets, timelines, publication strategies, and regulatory compliance requirements into program strategy.
  • Clinical and regulatory documentation: Author and review the translational medicine components of development plans, study protocols, clinical study reports, regulatory submissions, and other clinical and regulatory documents.
  • External scientific engagement: Lead scientific collaborations and interactions with therapeutic-area key opinion leaders in partnership with Medical Affairs, Commercial, and other functions.
  • Scientific expertise: Maintain current knowledge of the primary scientific literature, state-of-the-art technologies, and emerging concepts in immunology.

Qualifications

  • Education and experience: PhD, PharmD, or MD with at least 6 years of relevant experience, or MS with at least 8 years of relevant experience, in the pharmaceutical industry or an equivalent setting. Substantial knowledge of translational and precision medicine science is required. The position level will be determined based on experience.
  • Scientific expertise: Strong scientific background in immunology or a related field, supported by a relevant publication record.
  • Translational leadership and assay development: Demonstrated leadership in translational science, including the use of pharmacodynamic, predictive, and exploratory biomarkers. Experience developing assays, such as ligand-binding assays, IHC/IF, gene expression profiling, or flow cytometry, is preferred.
  • Data analysis and visualization: Familiarity with data management and visualization tools, with experience collaborating with computational biologists to analyze complex clinical trial data sets.
  • Therapeutic-area expertise: Expertise in rheumatology is highly desirable.
  • Clinical development knowledge: Knowledge of clinical trial methodology, protocol design, regulatory requirements governing clinical trials, companion diagnostics, and development strategy is preferred.
  • Program and team management: Ability to manage clinical translational programs and cross-functional teams with moderate supervision.
  • Communication and organization: Excellent written and verbal communication skills, with the ability to present results clearly and concisely. Strong organizational skills, attention to detail, effective time management, and adaptability to changing priorities are essential.
  • Collaboration: Strong interpersonal and collaboration skills, with the ability to work effectively in a team-oriented, matrixed environment and navigate conflict constructively.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
  • This job is eligible to participate in our long-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Skills Required

  • PhD, PharmD, or MD with at least 6 years of relevant experience in the pharmaceutical industry or equivalent setting
  • MS with at least 8 years of relevant experience in the pharmaceutical industry or equivalent setting
  • Substantial knowledge of translational and precision medicine science
  • Strong scientific background in immunology or a related field
  • Relevant publication record
  • Leadership experience in translational science
  • Experience using pharmacodynamic, predictive, and exploratory biomarkers
  • Experience developing assays such as ligand-binding assays, IHC/IF, gene expression profiling, or flow cytometry
  • Familiarity with data management and visualization tools
  • Experience collaborating with computational biologists to analyze complex clinical trial datasets
  • Expertise in rheumatology
  • Knowledge of clinical trial methodology, protocol design, clinical trial regulatory requirements, companion diagnostics, and development strategy
  • Ability to manage clinical translational programs and cross-functional teams with moderate supervision
  • Excellent written and verbal communication skills
  • Strong organizational skills, attention to detail, time management, and adaptability
  • Strong interpersonal and collaboration skills in a matrixed environment

AbbVie Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.

  • Retirement Support — Retirement programs are portrayed as a standout, with a dollar‑for‑dollar 401(k) match up to 6% and an additional annual company contribution based on age and service. Feedback suggests this materially boosts perceived total compensation for many U.S. employees.
  • Parental & Family Support — Paid parental and caregiver leave are emphasized, including up to 12 weeks of fully paid parental leave for all parents and 4 weeks of paid caregiver leave in the U.S. Feedback suggests these policies are a meaningful differentiator for employees balancing family needs.
  • Leave & Time Off Breadth — Time off is described as extensive, with tiered vacation that scales with tenure, 17 company holidays, and two paid volunteer days in the U.S. Feedback suggests the breadth of leave contributes notably to overall benefits satisfaction.

AbbVie Insights

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The Company
HQ: North Chicago, IL
56,000 Employees
Year Founded: 2013

What We Do

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.

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