Analytical Science and Technology Senior Scientist

Posted 13 Days Ago
Be an Early Applicant
Boston, MA, USA
Hybrid
120K-180K Annually
Senior level
Biotech • Pharmaceutical
The Role
Leads commercial analytical activities for cell and gene therapy products, including analytical method validation, technology transfer, testing oversight, continuous improvement, and lifecycle management. Authors and reviews SOPs, protocols, and technical reports while ensuring compliance with GMP and ICH, USP, and EMA requirements. Partners with analytical and process development, manufacturing, supply chain, quality teams, CDMOs, and contract laboratories to support launch readiness and commercial product lifecycle management.
Summary Generated by Built In

Job Description

General Summary:

The Senior Scientist, Analytical Sciences & Technology (AS&T), plays a critical role in the Commercial Manufacturing & Supply Chain team. You will be responsible for providing strong expertise with biological assays and analytical requirements to ensure launch readiness and lifecycle management for the commercial Cell and Gene therapy (CGT) portfolio.

Key Duties and Responsibilities:

  • Accountable for the success of commercial analytical activities, prioritization, and execution to meet program commitments
  • Subject Matter Expertise (SME) for ensuring the robustness of analytical methods and commercial testing requirements
  • Author and/or review technical documents, including method SOP, study protocol and technical report
  • Partners effectively with internal and external functions for commercial analytical technology transfer
  • Primary responsibilities extend to analytical method validations, continuous improvement, and lifecycle management
  • Collaborate with Vertex cross-functions, including Analytical Development, Process Development, Commercial Manufacturing, Supply Chain, Quality teams, Vertex Partners, and Contract Test labs.
  • Provides oversight for analytical testing and method performance executed at CDMOs and contract testing labs
  • Knowledge and Skills:

  • Demonstrated expertise in analytical method development, characterization, and qualification/validation for biologics
  • Knowledgeable in ICH/USP/EMA guidelines with a strong GMP background, CGT related preferred
  • Experience managing contract (CTO/CDMO) analytical testing, highly desirable
  • Experience with technical support of commercial biological products and cGMP manufacturing
  • Ability to prioritize objectives from multiple projects and adhere to scheduled timelines while maintaining flexibility and efficiency
  • Excellent technical writing skills, and communication skills with the proven ability to build open and collaborative
  • Hands-on experience with methods related to CGT products, prefer in-vitro cell-based functional, potency and/or microbiology assays
  • Education and Experience:

  • Bachelor’s degree or above in Science or related discipline
  • 6 years of experience in the pharmaceutical/biopharmaceutical industry with increasing project the equivalent combination of education and experience

  • At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

    Pay Range:

    $120,000 - $180,000

    Disclosure Statement:

    The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

    At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

    Flex Designation:

    Hybrid-Eligible Or On-Site Eligible

    Flex Eligibility Status:

    In this Hybrid-Eligible role, you can choose to be designated as: 
    1.    Hybrid: work remotely up to two days per week; or select
    2.    On-Site: work five days per week on-site with ad hoc flexibility.

    Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

    #LI-Hybrid
     

    Company Information

    Vertex is a global biotechnology company that invests in scientific innovation.

    Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

    Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

    Skills Required

    • Bachelor's degree or higher in science or a related discipline
    • Six years of experience in the pharmaceutical or biopharmaceutical industry, with increasing responsibility
    • Expertise in analytical method development, characterization, qualification, and validation for biologics
    • Knowledge of ICH, USP, and EMA guidelines
    • Strong GMP and cGMP experience
    • Experience providing technical support for commercial biological products and cGMP manufacturing
    • Ability to manage multiple projects, prioritize objectives, and meet scheduled timelines
    • Excellent technical writing and communication skills
    • Experience managing analytical testing through contract testing organizations or CDMOs
    • Cell and gene therapy experience
    • Hands-on experience with in-vitro cell-based functional, potency, or microbiology assays

    Vertex Pharmaceuticals Compensation & Benefits Highlights

    The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.

    • Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
    • Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
    • Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.

    Vertex Pharmaceuticals Insights

    Am I A Good Fit?
    beta
    Get Personalized Job Insights.
    Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.

    The Company
    HQ: Boston, MA
    5,000 Employees
    Year Founded: 1989

    What We Do

    Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.

    Similar Jobs

    Aurion Biotech, Inc. Logo Aurion Biotech, Inc.

    Scientist

    Healthtech • Biotech • Pharmaceutical
    In-Office
    Cambridge, MA, USA
    140K-155K

    Benchling Logo Benchling

    Technology Operations Engineer

    Cloud • Healthtech • Social Impact • Software • Biotech
    Hybrid
    Boston, MA, USA
    605 Employees
    81K-109K Annually

    NinjaOne Logo NinjaOne

    Senior Full-stack Engineer

    Information Technology • Productivity • Software • Infrastructure as a Service (IaaS)
    Remote or Hybrid
    19 Locations
    2000 Employees
    150K-200K Annually

    NinjaOne Logo NinjaOne

    Senior Software Engineer

    Information Technology • Productivity • Software • Infrastructure as a Service (IaaS)
    Remote or Hybrid
    18 Locations
    2000 Employees
    160K-200K Annually

    Similar Companies Hiring

    SOPHiA GENETICS Thumbnail
    Software • Healthtech • Biotech • Big Data • Artificial Intelligence
    Boston, MA
    450 Employees
    Pfizer Thumbnail
    Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
    New York, NY
    121990 Employees
    Cencora Thumbnail
    Healthtech • Logistics • Pharmaceutical
    Conshohocken, PA
    51000 Employees

    Sign up now Access later

    Create Free Account

    Please log in or sign up to report this job.

    Create Free Account