Job Description
At Vertex, we continue to invest in a future-ready workforce where AI helps people strengthen expertise, improve decision-making and create greater impact for our people and patients. We are looking for a Director, AI Transformation Operations to build the operating model that helps Vertex move AI reinvention projects from strategic decisions to coordinated execution.
Reporting to the VP, AI Transformation, you will connect strategy, governance, and delivery across Vertex’s AI transformation, translating portfolio decisions into coordinated action, keeping teams aligned, and creating the visibility and accountability to deliver with clarity and speed.
You will run the governance forums that guide the transformation, equipping leaders with the information, analysis, and stakeholder input needed to make timely decisions. You will turn those decisions into clear actions, responsibilities, and timelines, track follow-through, and keep leaders informed of progress, outstanding decisions, and areas that need their support.
To succeed, you will create scalable ways of working that strengthen decision-making, coordination, and follow-through, continually improving how the Transformation Office operates and the quality and pace of execution. You will model responsible use by continuously learning, applying AI to innovate your own work, and championing practices that create value.
Key Duties & Responsibilities:
- Governance planning. Maintain an integrated calendar of governance forums, decisions, milestones, and required inputs so work reaches the right leaders at the right time.
- Governance forum coordination. Coordinate the forums that guide Vertex’s AI transformation, including agendas, materials, stakeholder input, decisions, and follow-through.
- Decision preparation. Work across AI Transformation Strategy, Finance, Workforce Strategy & Innovation, Data Technology & Engineering, governance teams, and functional leaders to assemble the information and analysis needed for timely decisions.
- Decision follow-through. Translate governance and portfolio decisions into clear actions, responsibilities, timelines, and conditions; maintain a reliable record of commitments and open questions; and track progress through completion.
- Executive visibility and communications. Prepare concise, decision-oriented materials and updates that keep executive leaders, governance forums, and key stakeholders current on decisions, commitments, follow-through, and areas where leadership involvement is needed.
- Execution alignment. Keep decisions, responsibilities, actions, and timelines aligned across the teams contributing to the transformation.
- Transformation Office coordination. Manage the planning and follow-through needed to keep the Transformation Office focused on its priorities and connected to the broader portfolio.
- Scalable ways of working. Create and continually improve practical processes, tools, and templates that strengthen coordination and accountability across the transformation.
- AI-enabled operations. Use AI and automation to streamline work, improve the quality and timeliness of information, and surface insights that support better decisions.
Knowledge and Skills:
- Strong knowledge of executive governance, decision processes, transformation office operations, and cross-functional coordination.
- Ability to translate strategic and portfolio decisions into clear actions, responsibilities, timelines, conditions, and follow-through.
- Ability to design and coordinate governance forums, including decision requirements, agendas, stakeholder input, executive materials, records, and action tracking.
- Strong executive-writing and synthesis skills, with the ability to turn complex information into concise, decision-oriented materials and updates.
- Strong organizational judgment, with the ability to anticipate information needs, maintain momentum, and surface areas requiring leadership involvement.
- Ability to create scalable processes, tools, templates, and working practices that improve coordination without adding unnecessary complexity.
- Strong relationship-building and influence skills across functions, including the ability to establish shared expectations and maintain accountability without direct authority.
- Practical fluency with AI and automation tools and emerging AI capabilities, with the ability to use them responsibly to streamline work, improve the timeliness and quality of information, and surface useful insights.
- Ability to manage multiple concurrent governance activities, decisions, actions, and stakeholder needs in a fast-moving environment.
Education and Experience:
- Bachelor’s degree in business, operations, organizational management, communications, or a related field – or relevant experience
- Advanced degree preferred.
- Typically requires 10 or more years of experience in enterprise operations, transformation office operations, executive governance, or strategic program coordination, or the equivalent combination of education and experience.
- Demonstrated experience coordinating governance forums and decision processes for a complex, enterprise-wide transformation or portfolio.
- Experience preparing concise, decision-oriented materials for senior executives and translating leadership decisions into clear actions, responsibilities, and timelines.
- Experience maintaining disciplined follow-through across multiple functions, stakeholder groups, and concurrent priorities.
- Experience designing and improving scalable processes, governance routines, action-tracking practices, or management information that strengthen coordination and accountability.
- Experience working across strategy, Finance, technology, workforce, governance, and business teams in a complex, matrixed organization.
Pay Range:
$185,400 - $278,200Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Skills Required
- Bachelor's degree in business, operations, organizational management, communications, or a related field, or relevant equivalent experience
- 10 or more years of experience in enterprise operations, transformation office operations, executive governance, or strategic program coordination, or equivalent education and experience
- Experience coordinating governance forums and decision processes for a complex, enterprise-wide transformation or portfolio
- Experience preparing concise, decision-oriented materials for senior executives and translating leadership decisions into actions, responsibilities, and timelines
- Experience maintaining disciplined follow-through across multiple functions, stakeholder groups, and concurrent priorities
- Experience designing and improving scalable processes, governance routines, action-tracking practices, or management information
- Experience working across strategy, Finance, technology, workforce, governance, and business teams in a complex, matrixed organization
- Advanced degree
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
