This is a hybrid position and must be located within 100 miles of any of the Mayo Clinic campuses for on-site expectations based on business needs.
This role sits within Financial and Accounting Services, and this group is primarily focused on time series analytics and Generative AI Solutions tailored for finance applications, not clinical.
AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
As an AI/ML Engineer, you may work on the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will work on the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
• Working on component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
• Collaborating with a multidisciplinary team, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
• Interpreting / analyzing data to inform strategic decisions and communicate complex findings in easily understandable terms to bridge the gap between AI technologies and clinical applications.
• Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to design, develop and deploy end-to-end AI solutions for healthcare applications.
• Participating in the engineering of systems crucial for developing and deploying AI solutions.
• Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
• Contributing to implementing the best practices and standards for AI development and deployment methodologies, tools, and platforms.
• Providing training and education to healthcare staff on the use of AI tools and technologies.
A master’s degree in engineering, computer science, mathematics, health science, or a related field and 1 year experience,
OR
A bachelor’s degree with 3 years of experience.
• Experience applying AI and machine learning in production environments or similar highly regulated or technology focused industries, showcasing an understanding of healthcare technology.
• Skill in cloud infrastructure environment and software development tools.
• Experience working with large, complex, and heterogeneous data sets, preferably in healthcare.
• Skill in AI/ML techniques and frameworks.
• History of collaborating across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
• Familiarity with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
• Strong interpersonal, communication, and time management skills.
Preferred Expertise in delivering time series analytical models and/or agentic solutions in Copilot Studio or Google.
Preferred Qualifications:
• A Ph.D. or other doctorate degree is preferred.
• Expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, and Generative AI, with proficiency in tools like Python, TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
• Knowledge of the healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
• Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different project scenarios.
• Expertise in user-centered design, human factors engineering, usability testing methodologies, and evaluation across AI product development. Ability to conduct expert reviews using established usability practices and methods. Presents findings in easy-to-understand terms for the business or clinical practice.
• Ability to articulate complex technical concepts to diverse audiences, facilitating clear understanding and engagement from technical and non-technical stakeholders.
• Ability to manage a varied workload of projects with multiple priorities and stay current on healthcare trends.
• Experience with healthcare industry informatics standards, best practices, and common data models.
**This vacancy is not eligible for sponsorship / we will not sponsor or transfer visas for this position.
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Master's degree in engineering, computer science, mathematics, health science, or related field plus 1 year experience, OR Bachelor's degree plus 3 years experience
- Experience applying AI and machine learning in production environments or regulated industries
- Skill with cloud infrastructure environments and software development tools
- Experience working with large, complex, heterogeneous data sets (preferably healthcare)
- Skill in AI/ML techniques and frameworks (deep learning, NLP, computer vision, LLMs)
- Experience designing, testing, and maintaining CI/CD pipelines and automated MLOps workflows
- History of collaborating across diverse teams and communicating complex technical concepts to non-technical stakeholders
- Familiarity with best practices in data engineering, data science, AI engineering, and MLOps communities
- Strong interpersonal, communication, and time management skills
- Preferred: Expertise in delivering time series analytical models and/or agentic solutions in Copilot Studio or Google
- Preferred: Ph.D. or other doctorate degree
- Preferred: Proficiency with Python, TensorFlow, PyTorch, scikit-learn, Keras
- Preferred: Knowledge of healthcare domain (clinical workflows, EHRs, regulatory requirements, informatics standards)
- Preferred: Familiarity with systems/quality engineering best practices, regulatory standards, and compliance frameworks
- Preferred: Expertise in user-centered design, human factors, and usability testing methodologies
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.


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