AFM Scientist

Posted Yesterday
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Houston, TX, USA
In-Office
Expert/Leader
Healthtech • Biotech • Nanotechnology • Pharmaceutical
The Role
The AFM Scientist will conduct AFM research, develop measurement protocols, ensure data quality, provide training, and support clinical operations. Requires on-site work and travel in the USA.
Summary Generated by Built In

About ARTIDIS

ARTIDIS is a clinical-stage health-tech start-up founded in Basel, Switzerland, that has developed the first nanomechanical biomarker for cancer diagnosis and treatment optimization. The ARTIDIS nanotechnology platform integrates different types of clinical data into the ARTIDISNET digital platform, allowing physicians to significantly shorten the current diagnostic process and benefit both the patient and the healthcare system. ARTIDIS enables professionals to design personalized cancer treatment plans tailored to individual patients' needs and desired outcomes. 

Job Purpose

We are seeking an AFM Scientist to join our Application Support team. In this role, you will leverage your advanced AFM expertise to support pre-clinical and clinical operations, develop and optimize measurement protocols, and ensure the highest standards of data quality, reproducibility, and regulatory compliance. You will work closely with research teams, clinical partners, and customers to deliver exceptional support, training, and troubleshooting. This position requires 100% on-site availability and approximately 50% travel within the USA.

Duties and Responsibilities

  • Conduct pre-clinical and clinical AFM-based research to characterize the nanomechanical properties of solid tumors.

  • Develop and refine measurement protocols, including sample preparation methods, measurement standards, and custom specimen holder design.

  • Optimize and execute measurement routines both at ARTIDIS facilities and customer sites.

  • Prepare technical documentation, study reports, work instructions (WIs), and test plans in compliance with FDA regulations and ISO 13485 standards.

  • Provide on-site support and troubleshooting for clinical and research teams, adapting to hospital and laboratory schedules.

  • Improve AFM data analysis pipelines, conduct advanced statistical analyses, and support analytical validation testing.

  • Validate the performance of new devices and measurement tools on biological samples in clinical settings.

  • Develop training protocols and education for internals and externals.

  • Gather and document user requirement and feedback to guide ongoing development and product improvements.

  • Maintain strong relationships with hospital partners and customers through regular site visits and workflow support.

Qualifications

  • Ph.D. or equivalent in Physics, Biomedical Engineering, Materials Science, or a related field with a focus on AFM or scanning probe microscopy.

  • Proven experience in AFM measurements of biological samples, tissue/cell nanomechanics, sample preparation, and quantitative data analysis.

  • Familiar with medical device operations, ISO 13485, FDA guidelines, CE Marking, and international regulatory frameworks.

  • Skilled in technical training, application support, and tailoring AFM solutions to end-user needs.

  • Strong ability to troubleshoot AFM systems, optimize measurement workflows, and collaborate in multidisciplinary environments.

  • Willingness and ability to travel frequently in the USA.

  • Excellent written and verbal skills for technical documentation, presentations, and scientific discussions.

  • Ability to manage multiple AFM-related projects in a fast-paced, evolving environment.

Working Conditions

You will join a highly motivated international team in a dynamic start-up environment. This role offers the opportunity to rapidly expand your expertise, take ownership of critical AFM projects, and contribute to impactful cancer research. We value initiative, direct communication, and a team spirit that goes the extra mile. Your efforts will be rewarded with challenging projects, meaningful contributions to patient care, and a competitive compensation package with performance-based bonuses.

Skills Required

  • Ph.D. in Physics, Biomedical Engineering, Materials Science, or related field
  • Proven experience in AFM measurements of biological samples
  • Familiarity with medical device operations, ISO 13485, FDA guidelines
  • Skilled in technical training and application support
  • Strong troubleshooting skills with AFM systems
  • Excellent written and verbal communication skills
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The Company
73 Employees
Year Founded: 2017

What We Do

ARTIDIS AG is a clinical-stage health technology company that aims to set the gold standard in tissue analysis and therapy optimization. By combining its proprietary nanotechnology platform for rapid tissue analysis with a holistic data solution, ARTIDIS accelerates drug discovery, tissue engineering, and personalized treatment. The company focuses its research and development efforts on solid tumors to enhance responses to chemotherapy, immunotherapy, and cell therapies, driving precision in cancer care.

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