Jobs at Xenon Pharmaceuticals Inc.

Provide scientific leadership for clinical study design, execution, analysis, and reporting across assigned neuroscience programs. Support protocol development, safety and efficacy data review, regulatory documentation, cross-functional collaboration with CROs and partners, investigator interactions, and development of SOPs and study materials to ensure scientifically rigorous, operationally feasible clinical development.

Lead scientific contribution to design, execution, analysis, and interpretation of clinical trials for neuroscience programs. Draft and review clinical and regulatory documents, collaborate cross-functionally and with CROs/investigators, monitor safety and efficacy data, perform literature review, support study start-up and training, and help develop development strategies, SOPs, and scientific communications.

Lead and optimize the Commercial Review Committee (CRC/MLR) process to ensure compliant, efficient marketing review. Partner across Marketing, Regulatory, Legal, Medical Affairs, Compliance, and IT to manage systems (e.g., Veeva), vendors, and content lifecycle. Drive process improvements, KPI reporting, training, and roadmap for content operations. Manage vendor/agency relationships, forecasting, capacity planning, and governance; recruit and lead staff as needed. Support pre-launch activities with some international travel.

Lead commercial data management for a pre-launch/launch biotech product: build governed commercial data ecosystem, own MDM for HCP/HCO/payer identities, manage data quality and stewardship, coordinate vendors and data platforms, translate business needs to data requirements, and enable reporting-ready datasets to support analytics and launch decision-making.

Lead payer engagement for the West region to secure rapid formulary coverage and access parity for Xenon products. Build and maintain strategic payer relationships, develop account plans, negotiate contracts, align with Medical Affairs and Value & Access, support field pull-through and training, deliver payer insights, manage budgets, recruit and coach staff, and represent Xenon at industry conferences. Some international travel may be required.

Lead development and execution of US HCP education strategy to support brand and launch objectives. Design and run peer-to-peer programs, congress strategy, digital learning, workshops and advisory boards. Integrate cross-functionally with Medical, Sales, Market Access, and Compliance. Manage KOLs, agencies, budgets, KPIs, and analytics to drive HCP adoption and launch readiness.

Lead U.S. payer market access for Azetukalner, building relationships with national/regional payers, securing formulary coverage and contracting, developing account strategies, collaborating with Commercial, Medical Affairs, and HEOR, supporting field teams, and representing Xenon at industry conferences to ensure rapid patient access.

The Director of Pricing and Contracting will develop and implement U.S. pricing strategies and payer contracting frameworks while collaborating cross-functionally to ensure successful market access and financial performance for Xenon's products.

Lead design and implementation of enterprise integration and data engineering. Manage integration capabilities, establish data governance, and ensure compliance and quality of data flows across applications.

Coordinate high-volume full-cycle recruitment and candidate experience across Canada and the U.S.; manage onboarding, employee life-cycle transactions, HRIS data entry (Dayforce), and support Workday implementation. Maintain ATS records, schedule interviews, facilitate background checks, prepare job postings and employment agreements, collaborate with payroll, and support HR administration and projects. Ensure process accuracy, confidentiality, and operational improvements in a fast-paced biopharma environment.

Manage the end-to-end supply chain strategy, ensuring compliance and efficiency from clinical development to commercialization, while leading cross-functional teams and optimizing processes.

The Executive Director, Total Rewards will manage and design compensation strategies, ensuring alignment with business goals, compliance, and market competitiveness to retain top talent in North America.

The Director, Forecast & Research will lead forecasting, market research, and insights generation for Xenon's epilepsy portfolio, collaborating with cross-functional leaders to deliver actionable analytics.

The Executive Director, Total Rewards will lead total compensation strategies to attract and retain talent, managing salary, benefits, and recognition programs in a strategic HR role.

The Senior Manager will oversee regulatory submission processes, manage external publishing vendors, support project teams, maintain regulatory calendars, and enhance operational functions within the Regulatory Affairs department.

The Senior Manager/Associate Director, Access Marketing will execute the azetukalner access strategy, develop payer value proposition, and manage patient access materials, collaborating with internal and external stakeholders.

The Manager/Senior Manager will lead data management for clinical trials, oversee vendors, design databases, and ensure compliance with regulations.

The Manager/Senior Manager will lead data management activities for clinical trials, collaborating across functions to design databases and manage vendors, while ensuring compliance with regulations.

Manage clinical trials for multiple Phase 3 studies, ensuring collaboration with teams, vendor management, adherence to regulations, and effective timelines. Train new staff and oversee trial best practices.

Oversee multiple Phase 3 clinical trials, manage study operations, collaborate with teams, and ensure adherence to regulatory standards, while mentoring staff.