Onyx Bio

> Onyx is a research collective in Berkeley, California, building a virtual immune system: a model of how real people respond to infection, inflammation, and treatment. > > > Most immune data is a snapshot. Onyx follows the same people over time and around key clinical events, such as changes in treatment, vaccination, or infection. Our members, healthy adults and people with autoimmune disease, take part as partners in discovery. > > Every sample is processed in our own lab in Berkeley, CA. We generate single-cell transcriptomics with T- and B-cell receptor tracking, proteomics covering about 1,000 plasma proteins, metabolomics, and genomics, linked to longitudinal clinical data at the participant level. > > Biopharma and AI teams use Onyx data to develop medicines, understand complex biology, identify new targets, and stratify clinical study cohorts. They can access existing datasets or assemble a custom cohort focused on the biology they want to understand. > > Onyx was founded by Roger Chen (CEO) and Amit Lakhani (CTO). >