Nabsys

Nabsys uses proprietary electronic nano-channel detectors to analyze long DNA molecules at high velocity. Electronic detection enables Nabsys to achieve significantly higher resolution than can be obtained using optical mapping methods. Nabsys HD-Mapping™ solid-state electronic nano-channel detectors build whole genome maps with sub-diffraction-limit resolution that are truly high definition. These maps offer compelling advantages for the analysis of structural variation, the assembly of genomes, and as a method for confirming putative variants called using other technologies. HD-Mapping works by adding sequence-specific tags to long DNA molecules. These molecules pass through the nano-detectors at high velocity using a combination of electrophoretic and hydrodynamic control. The detectors report the locations of the sequence-specific tags on the molecules. The information is then analyzed by Nabsys analytical software. Key application areas that are enabled by Nabsys include: • De Novo Assembly • Structural Variant Discovery • Variant Verification • Microbiome Analysis • Metagenome Characterization • Hybrid Assembly Nabsys provides the complete solution for electronic genome mapping. The Nabsys HD-Mapping platform includes: • HD-Mapping instrument • Electronic nano-channel detector chips • Complete run reagent cartridge • Sample prep kit • Comprehensive control and data analysis software Nabsys HD Mapping provides routine, accurate, cost-effective analysis of genomic structural information. The HD-Mapping platform employs fully electronic detection of tagged single DNA molecules to provide significantly higher sensitivity, accuracy, scalability and speed of detection in comparison to existing mapping technologies. Single-molecule reads, hundreds of kilobases in length, have high resolution and low error rates, resulting in high information content per read.