Teams at Monte Rosa Therapeutics

Designs and leads preclinical in vivo pharmacology studies in mouse models of immunology, inflammation, and oncology. Performs animal procedures, pharmacokinetic/pharmacodynamic studies, immune profiling, flow cytometry, tissue processing, and ex vivo assays. Interprets and presents findings, troubleshoots experiments, coordinates cross-functional study execution, mentors junior scientists, and supports animal facility operations, protocols, and standard operating procedures.

Develops and executes cellular assays supporting drug discovery, compound profiling, and mechanism-of-action studies. Responsibilities include mammalian cell culture, CRISPR/Cas9 engineering, engineered cell-line characterization, molecular biology, protein analysis, functional cellular readouts, assay optimization, automation, quantitative data analysis, and workflow scale-up. The contractor collaborates with internal teams and CROs, maintains experimental records and materials, troubleshoots independently, and follows laboratory safety and quality procedures.

Supports and administers clinical operations systems including EDC, IRT/RTSM, eTMF, and CTMS. Builds and maintains AWS-based data pipelines and integrations for clinical, operational, biomarker, and assay data. Automates manual processes, monitors pipeline health, supports audit readiness and data integrity, and partners with Clinical Operations, Clinical Data Science, Biomarkers, CROs, vendors, and IT teams.