Oracle and AMD Partner to Launch AI Data Center Supercluster

Oracle-run data centers will be powered by tens of thousands of AMD’s latest-model AI chips.

Written by Ashley Bowden
Published on Oct. 14, 2025
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Image: Shutterstick
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Rose Velazquez | Oct 14, 2025

Cloud infrastructure giant Oracle is furthering its ongoing partnership with Advanced Micro Devices, a computer chip manufacturer based in California. The companies will collaborate to implement an Oracle-run data center supercluster powered by AMD’s most advanced AI chips.

Launched on Oracle Cloud Infrastructure, the supercluster will run on 50,000 AMD Instinct MI450 Series graphics processing units in the initial phase, starting in the third quarter of 2026. The companies plan to further the partnership, expanding into 2027 and beyond. The supercluster will leverage AMD’s Helios rack design, a vertically-optimized, rack-scale architecture intended to provide increased performance, scalability and energy efficiency.

The Helios server racks combine MI450 GPUs with an AMD-designed central processing unit, which will serve as the main computer brain in every data center, according to reporting by The Wall Street Journal. The data center cluster will use the equivalent of 200 megawatts of computing power.

Oracle and AMD’s partnership comes as companies work to secure access to the latest AI processors. Their goal is to enable large-scale AI training and inference as demand for AI capacity increases in time with fast-advancing AI models. Through their collaboration, Oracle and AMD want to provide more flexible, open compute solutions designed for immense scale and efficiency, enabling organizations to train and run workloads required for next-generation AI models.

“By bringing together the latest AMD processor innovations with OCI’s secure, flexible platform and advanced networking powered by Oracle Acceleron, customers can push the boundaries with confidence,” Mahesh Thiagarajan, EVP for the OCI Security and Developer Platform, said in a statement. “Through our decade-long collaboration with AMD… we’re continuing to deliver the best price-performance, open, secure and scalable cloud foundation in partnership with AMD to meet customer needs for this next era of AI.”

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