Top Remote Senior Level Jobs in Des Moines, IA

Lead and scale a 23-person global B2B SaaS support organization through three managers. Own support operations, staffing capacity, SLAs, Zendesk administration and reporting, metrics, escalations, coaching, and customer experience. Manage Swift CX and AI-assisted triage, partner with Product and Engineering on systemic issues and tooling, and report performance and resourcing needs to executive leadership. Engage directly with customers during high-visibility escalations.

Owns renewals, retention, upsells, and cross-sells for mid-sized to large public transit agency customers. Responsibilities include managing account plans and success plans, building pipeline, leading the sales cycle, preparing proposals and ROI presentations, demonstrating the platform, navigating procurement and RFPs, meeting quotas, and collaborating cross-functionally to expand customer value.

Lead Vertex’s global Oracle partnership strategy and execution, including executive relationship management, joint business planning, solution integrations, co-selling, partner enablement, commercial alignment, and go-to-market initiatives. Coordinate cross-functional product, sales, marketing, solutions, customer success, and legal teams. Monitor pipeline, revenue, adoption, and strategic performance while managing risks and corrective actions. Lead a matrixed partnership team and serve as the executive spokesperson for the Oracle relationship.

Own a named portfolio of 25–50 Fortune 500 accounts across prospecting, enterprise sales, onboarding, enrollment adoption, expansion, and renewal. Build strategic account plans, manage complex stakeholder relationships, lead RFPs and negotiations, forecast multiple pipelines, and partner with implementation, customer success, marketing, product, and finance teams. Maintain executive-level relationships while driving durable, multi-year revenue growth.

Leads investor relations and corporate communications strategy for a clinical-stage biotech company. Translates complex scientific and clinical developments into compelling investor, analyst, media, and stakeholder messaging. Responsibilities include managing filings, press releases, conferences, roadshows, corporate content, executive communications, media relations, crisis response, spokesperson preparation, brand campaigns, and regulatory accuracy while collaborating with Finance, Legal, executives, and product teams.

Leads strategic planning, budgeting, forecasting, and financial analysis for the risk exchange platform. Partners with finance, accounting, actuarial, and distribution teams; analyzes operational and insurance results; prepares management reporting; supports monthly close; and presents insights to senior leadership. Drives Pigment planning-platform adoption and improves FP&A processes through AI, automation, documentation, and digital tools.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Lead paid acquisition strategy across complex, multichannel client programs, owning budgets, targeting, creative testing, forecasting, and optimization. Audit measurement, model payback, LTV, CAC, and ROI, and translate data into client decisions. Partner with CRO, analytics, engineering, lifecycle, and creative teams to deliver integrated programs. Influence executive stakeholders, identify account expansion opportunities, support business development, coach junior strategists, and build scalable AI-assisted workflows and brand-specific AI agents.

Build and lead Replicant’s company-wide AI enablement program. Develop MCP integrations, shared agents, agent identity management, enterprise tool connections, reusable AI workflows, and cost-visibility mechanisms. Partner with Sales, Delivery, Finance, People, Engineering, and other teams to identify opportunities, implement solutions, promote AI literacy, and develop internal champions. Optimize AI systems through model routing, prompt caching, better agent design, and secure infrastructure.

Leads employee benefits and total rewards strategy, including self-funded health plans, compensation programs, vendor relationships, HRIS administration, compliance, claims analysis, cost containment, open enrollment, and executive reporting. Partners with leadership, Finance, and HR to optimize benefits, compensation, healthcare costs, and employee value.