MISSION
Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.
POSITION SUMMARY
The Zone Director is a second-line field leader responsible for driving commercial performance, building 4 high-performing Region Business Director (RBD) teams, and ensuring execution excellence across the liver portfolio. This role translates national strategy into regional impact, with a strong emphasis on rare disease expertise, patient-centricity, and cross-functional leadership.
Assigned Area: WA, OR, CA, NV, AZ, UT, ID MT, WY, CO, NM, TX, KS, SD, ND, OK. LA, AR, MO, IA, MN, WI, IL, KY, MS, AL
JOB FUNCTIONS/RESPONSIBILITIES
Enterprise Leadership
- Own and deliver Zone business performance across the liver portfolio with a strategic, big-picture mindset
- Drive change and innovation
- Develop and execute zone-specific business plans aligned to national strategy
- Analyze market trends, competitive dynamics, and performance data to inform actions
Team Leadership & Development
- Lead, coach, and develop first-line leaders to maximize team effectiveness
- Build a strong leadership pipeline and succession plans
- Foster a culture of accountability, engagement, and continuous improvement
Execution Excellence
- Ensure consistent and high-quality execution of brand strategy in the field
- Monitor KPIs and drive disciplined performance management
- Identify and scale best practices across regions
Cross-Functional Collaboration
- Partner with Marketing, Market Access, Medical Affairs, Patient Services and Operations
- Ensure alignment on strategy and coordinated execution
- Provide field insights to inform brand planning and lifecycle strategy
Market & Customer Engagement
- Maintain strategic relationships with key opinion leaders (KOLs) and top accounts
- Understand regional nuances in referral patterns and treatment pathways
- Support teams in navigating complex access and reimbursement environments
Compliance & Ethical Leadership
- Ensure all activities comply with regulatory, legal, and company policies
- Model integrity and patient-first decision making
- Reinforce a culture of compliance across the organization
QUALIFICATIONS
Education/Experience:
- Bachelor’s degree required; advanced degree preferred (MBA, etc.)
- 7+ years pharmaceutical/biotech experience, plus minimum of 5 years of leadership experience
- Successful experience leading leaders (second-line leadership) highly desired
- Significant rare disease and/or specialty experience
- Experience in rare liver disease a plus
- Proven success in product launches, ideally with first-in-class therapies and in competitive markets
- Demonstrated ability to build, lead, train and develop high-performing teams
- Proven success in sales leadership roles with the ability to inspire, influence and align teams
- Experience navigating complex rare disease patient journeys, including diagnosis, referral pathways, and difficult access to therapies
- Strong leadership presence with the ability to inspire, influence, and align teams
- Strong understanding of market access, payer dynamics, and patient services
- Demonstrated ability to lead in a matrixed organization
- High integrity, ethical standards, and commitment to compliance
- Thrives in a fast-paced, dynamic, and collaborative environment
- Able to travel frequently, up to 70% overnight travel and has a valid drivers’ license
#LI-REMOTE
Mirum Pharmaceuticals is committed to Equal Employment Opportunity (EEO) and to compliance with all Federal, State and Local laws that prohibit employment discrimination on the basis of race, age, national origin, ethnicity, religion, gender, gender identity, pregnancy, marital status, sexual orientation, citizenship, genetic disposition or characteristics, disability, veteran’s status or any other classification protected by applicable State/Federal/Local laws.
Mirum Pharmaceuticals provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures.
Skills Required
- Bachelor's degree
- Advanced degree (MBA, etc.)
- 7+ years pharmaceutical/biotech experience
- Minimum of 5 years leadership experience
- Successful experience leading leaders (second-line leadership)
- Significant rare disease and/or specialty experience
- Experience in rare liver disease
- Proven success in product launches, ideally with first-in-class therapies
- Demonstrated ability to build, lead, train and develop high-performing teams
- Proven success in sales leadership roles with ability to inspire, influence and align teams
- Experience navigating complex rare disease patient journeys, including referral pathways and access challenges
- Strong understanding of market access, payer dynamics, and patient services
- Demonstrated ability to lead in a matrixed organization
- High integrity, ethical standards, and commitment to compliance
- Thrives in a fast-paced, dynamic, and collaborative environment
- Able to travel frequently, up to 70% overnight
- Valid driver's license
Mirum Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mirum Pharmaceuticals and has not been reviewed or approved by Mirum Pharmaceuticals.
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Equity Value & Accessibility — Equity grants to new hires and an employee stock purchase plan make ownership more accessible and can boost total rewards when performance is strong. Public disclosures highlight frequent option/RSU inducements.
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Healthcare Strength — Comprehensive medical, dental, and vision coverage is employer-paid for employees, with added life, disability, and EAP support. This combination reduces financial burden and enhances overall wellbeing.
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Leave & Time Off Breadth — A broad time-off program includes multiple paid company holidays, a year-end shutdown, accrued vacation, and paid parental leave. This breadth provides additional rest periods beyond standard vacation.
Mirum Pharmaceuticals Insights
What We Do
Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. Mirum’s approved medication is LIVMARLI® (maralixibat) oral solution which is approved in the U.S. for the treatment of cholestatic pruritus in patients with Alagille syndrome one year of age and older. Mirum’s late-stage pipeline includes two investigational treatments for debilitating liver diseases affecting children and adults. Maralixibat (LIVMARLI), an oral ileal bile acid transporter (IBAT) inhibitor, is currently being evaluated in clinical trials for pediatric liver diseases and includes the MARCH Phase 3 study for progressive familial intrahepatic cholestasis (PFIC) and the EMBARK Phase 2b study for patients with biliary atresia. In addition, Mirum has an expanded access program open in Canada, Australia, the UK and several countries in Europe for eligible patients with Alagille syndrome. Mirum has submitted a Marketing Authorization Application to the European Medicines Agency for maralixibat for the treatment of cholestatic liver disease in patients with Alagille syndrome. Mirum’s second investigational treatment, volixibat, also an oral IBAT inhibitor, is being evaluated in three potentially registrational studies including the OHANA Phase 2b study for pregnant women with intrahepatic cholestasis of pregnancy, VISTAS Phase 2b study for adults with primary sclerosing cholangitis, and the VANTAGE Phase 2b study for primary biliary cholangitis.
