Frontier is looking for a VP of Finance to serve as a strategic finance partner to the CFO and executive leadership team. This is a broad finance leadership role that combines strong FP&A leadership with genuine fluency in technical accounting and SEC reporting — the ideal candidate is as comfortable leading the annual budget cycle as they are working through a complex accounting memo or registration statement disclosure. The VP of Finance will work in conjunction with the Controller, providing senior-level financial oversight and support, including direct ownership of SEC reporting readiness and technical accounting matters as the company scales toward and through a public company structure.
Requirements
What will you be doing?
SEC Reporting & Technical Accounting
- Own SEC reporting readiness and capital markets workstreams, drawing on prior experience with registration statements, periodic reporting (10-K/10-Q), or public company financial operations.
- Serve as a senior technical accounting resource in conjunction with the Controller, researching and documenting positions on complex or judgment-heavy accounting matters (revenue recognition, equity, leases, etc.).
- Lead SOX 404(a)/(b) readiness from a planning and controls-design perspective, partnering with the Controller to build out the control environment ahead of public company requirements.
- Build out investor-facing financial materials, messaging, and disclosure language in close coordination with the CFO.
- Support capital markets transactions (equity/debt offerings, registration statements) as they arise, including coordination with underwriters, auditors, and outside counsel.
FP&A & Business Partnership
- Lead annual budgeting, long-range planning, monthly forecasting, and variance analysis across all departments, with strong financial modeling as a core skill.
- Serve as a strategic financial business partner to R&D, Clinical, Regulatory, Medical, and G&A leaders, translating program and headcount plans into financial models.
- Build and maintain financial models supporting capital planning, cash runway analysis, and scenario planning for the Board and investors.
- Lead clinical trial and R&D accrual forecasting in partnership with the Controller and Clinical Development teams.
- Partner closely with the CFO on Board presentations, investor materials, and strategic planning; prepare Board-level financial reporting packages and actual-to-budget analyses.
- Drive finance systems and process improvements (planning tools, reporting automation) to scale the finance organization as the company grows.
- Provide ad hoc financial analysis and special project support to the CFO.
What are we looking for?
- Bachelor's degree in Finance or Accounting required; CPA strongly preferred given the technical accounting and SEC reporting scope of this role. MBA a plus.
- 15+ years of progressive finance experience, with a genuine dual fluency: strong FP&A/financial modeling skills AND hands-on technical accounting and SEC reporting experience — not just exposure to one side.
- Big Four public accounting background strongly preferred, ideally followed by industry experience at a biotech/life sciences company that scaled through significant growth (clinical-stage to commercial, or private to public).
- Direct, hands-on experience with SEC reporting cycles (10-K/10-Q), registration statements, and/or public company financial operations required.
- Experience with capital markets transactions and working alongside underwriters, external auditors, and outside counsel strongly preferred.
- Comfortable working in conjunction with a Controller and accounting team as part of a broader finance leadership structure — this role adds senior technical depth, not a duplicate accounting function.
- Clinical trial accounting and biotech/therapeutics industry experience preferred.
- Excellent communication skills, with the ability to translate financial and accounting detail into clear guidance for non-finance executives.
Benefits
- Health Care Plan (Medical, Dental & Vision)
- Retirement Plan (401k, IRA)
- Life Insurance (Basic, Voluntary & AD&D)
- Paid Time Off (Vacation, Sick & Public Holidays)
- Family Leave (Maternity, Paternity)
- Short Term & Long Term Disability
- Training & Development
- Free Food & Snacks
- Wellness Resources
- Stock Option Plan
At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $250,000 to $310,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.
This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.
Skills Required
- Bachelor's degree in Finance or Accounting
- 15+ years of progressive finance experience
- Direct, hands-on experience with SEC reporting cycles (10-K/10-Q) and registration statements
- Demonstrated dual fluency in FP&A/financial modeling and technical accounting
- CPA
- Big Four public accounting background
- Experience with capital markets transactions and working with underwriters, auditors, and outside counsel
- Biotech/therapeutics industry experience and clinical trial accounting
- MBA
- Excellent communication skills translating financial and accounting detail to non-finance executives
What We Do
Frontier Medicines, located in South San Francisco, CA and Boston, MA, is a precision medicine company that has pioneered a powerful discovery and development platform designed to generate medicines against disease-causing proteins previously considered undruggable. We are deploying our technologies in chemoproteomics, covalent drug discovery, and machine learning to develop a pipeline of groundbreaking medicines against the most important drivers of disease. Our lead program targets both the activated and inactive forms of KRAS G12C, a validated driver in a number of cancers that until recently has been undruggable. Our pipeline embodies our vision of bolding advancing science to defeat disease, starting with cancer.







