Translational Science Lead

Posted 7 Hours Ago
Be an Early Applicant
3 Locations
Hybrid
Expert/Leader
Artificial Intelligence • Healthtech • Professional Services • Analytics • Consulting
Where passion changes lives
The Role
Leads and expands ZS Discovery’s translational science practice for pharma and biotech clients. Responsibilities include developing biomarker, patient stratification, and patient-centered prediction offerings; engaging senior R&D stakeholders; originating business; creating reusable methodologies; building a global team; and establishing external thought leadership. The role requires deep expertise across the discovery-to-clinical-entry lifecycle, multi-modal biomedical data, computational methods, precision medicine, and AI applications in translational science.
Summary Generated by Built In
ZS is a place where passion changes lives. As a management consulting and technology firm focused on improving life and how we live it, we transform ideas into impact by bringing together data, science, technology and human ingenuity to deliver better outcomes for all. Here you'll work side-by-side with a powerful collective of thinkers and experts shaping life-changing solutions for patients, caregivers and consumers, worldwide. ZSers drive impact by bringing a client-first mentality to each and every engagement. We partner collaboratively with our clients to develop custom solutions and technology products that create value and deliver company results across critical areas of their business. Bring your curiosity for learning, bold ideas, courage and passion to drive life-changing impact to ZS.
#LI-AS4
ZS Discovery partners with pharmaceutical and biotech clients to accelerate the discovery of safer, more effective therapeutics. The team brings hands-on scientific expertise, advanced analytics, AI, and strategic consulting to help research organizations become more productive, more data-driven, and more confident in their decisions. As a venture within ZS building toward practice status, Discovery combines agility and innovation with the resources and knowledge of the broader firm.
Translational Science Lead
ZSD delivers successful projects in biomarker selection, patient segmentation, translational hypothesis validation, and multi-modal data integration and exploratory analytics, and demand for this work is growing. You'll bring deep expertise to that work, own an account, and contribute to how ZSD delivers translational science offerings, drawing on the firm's strengths in AI, bioinformatics, and data excellence.
What you'll do:
  • Refine and extend ZSD's translational science and patient-centered prediction offerings, hardening and innovating high impact capabilities spanning forward translation, reverse translation, and patient stratification
  • Engage senior R&D leaders at pharma and biotech organizations to prove market demand, originate engagements, and build a pipeline of opportunities in the translational science space
  • Move translational science capabilities from point solutions to a repeatable practice with reusable frameworks, accelerators, and methodologies the broader team can deliver
  • Develop and expand the global translational science team
  • Establish ZSD's external credibility in translational sciences and patient-centered prediction through thought leadership, conference presence, and published perspectives
  • Leverage and innovate ZSD's existing strengths in AI, bioinformatics, and data excellence
  • Serve as a domain-credible thought partner for senior R&D stakeholders, translating complex translational science challenges into actionable ZSD solutions

What you'll bring:
  • Advanced degree (PhD, MD, or equivalent) in a relevant scientific discipline: translational science, biomarker research, computational biology, statistical genetics, or related
  • 10+ years of experience in pharma R&D, a life sciences platform company, or a translational science function, with a focus on patient-centered prediction, biomarkers, or translational medicine
  • Experience spanning the discovery-development boundary; understanding the full research lifecycle from target identification through clinical entry
  • Deep familiarity with the data types used across the research lifecycle: trial biospecimens, on-study PD/ctDNA/MRD reads, real-world evidence (e.g., Tempus, Flatiron), population cohorts (e.g., UK Biobank, FinnGen, All of Us), and multi-modal omics (bulk and single-cell, spatial transcriptomics, methylation, imaging)
  • Credible as a thought partner with senior R&D leaders on patient-centered prediction topics; able to engage across both scientific and business dimensions
  • Experience defining and shaping a new offering, practice area, or capability
  • Strong analytical and computational orientation; familiarity with precision medicine tools, model-informed drug development, and AI applications in translational sciences
  • Experience in a consulting firm, life sciences platform company, pharma services organization, or pharma/biotech R&D environment preferred
  • Fluency in English
  • Client-first mentality
  • Intense work ethic
  • Collaborative spirit and problem-solving approach

How you'll grow:
  • Cross-functional skills development & custom learning pathways
  • Milestone training programs aligned to career progression opportunities
  • Internal mobility paths that empower growth via s-curves, individual contribution and role expansions

Perks & Benefits:
At ZS, your growth matters. We offer a comprehensive total rewards package that supports your health and well-being, financial future, time away, and professional development. With robust skills-building programs, multiple career progression paths, internal mobility, and a deeply collaborative culture, you'll have the opportunity to do meaningful work, expand your capabilities, and thrive as part of a global community. For details on total rewards in United States , visit ZS US office locations | Where we work | ZS .
Hybrid working model:
We are committed to giving our employees a flexible and connected way of working. A flexible and connected ZS allows us to combine work from home and on-site presence at clients/ZS offices for the majority of our week. The magic of ZS culture and innovation thrives in both planned and spontaneous face-to-face connections.
Travel:
Travel is a requirement at ZS for client facing ZSers; business needs of your project and client are the priority. While some projects may be local, all client-facing ZSers should be prepared to travel as needed. Travel provides opportunities to strengthen client relationships, gain diverse experiences, and enhance professional growth by working in different environments and cultures.
Considering applying?
At ZS, we honor the visible and invisible elements of our identities, personal experiences, and belief systems-the ones that comprise us as individuals, shape who we are, and make us unique. We believe your personal interests, identities, and desire to learn are integral to your success here. We are committed to building a team that reflects a broad variety of backgrounds, perspectives, and experiences. Learn more about our inclusion and belonging efforts and the networks ZS supports to assist our ZSers in cultivating community spaces and obtaining the resources they need to thrive.
If you're eager to grow, contribute, and bring your unique self to our work, we encourage you to apply.
ZS is an equal opportunity employer and is committed to providing equal employment and advancement opportunities without regard to any class protected by applicable law.
Work Authorization:
This position is not eligible for visa sponsorship. Candidates must have authorization to work in the United States that does not now or in the future require employer sponsorship.
To complete your application:
An on-line application, including a full set of transcripts (official or unofficial), is required to be considered.
NO AGENCY CALLS, PLEASE.
Find Out More At:
www.zs.com

Skills Required

  • Advanced degree such as a PhD, MD, or equivalent in translational science, biomarker research, computational biology, statistical genetics, or a related scientific discipline
  • 10+ years of experience in pharma R&D, a life sciences platform company, or a translational science function
  • Experience focused on patient-centered prediction, biomarkers, or translational medicine
  • Experience spanning discovery through development, including target identification through clinical entry
  • Deep familiarity with research lifecycle data, including trial biospecimens, pharmacodynamic and ctDNA/MRD reads, real-world evidence, population cohorts, and multi-modal omics
  • Ability to serve as a thought partner to senior R&D leaders across scientific and business topics
  • Experience defining or shaping a new offering, practice area, or capability
  • Strong analytical and computational orientation, including familiarity with precision medicine tools, model-informed drug development, and AI applications in translational sciences
  • Experience in a consulting firm, life sciences platform company, pharma services organization, or pharma/biotech R&D environment
  • Fluency in English
  • Client-first mentality
  • Intense work ethic
  • Collaborative spirit and problem-solving approach

What the Team is Saying

Ash Easwar
Suzanne Boyan
Kristina Sambucci
Callum Brazier
Michelle Lu
Mike Vula
Mina Labib
Judith Kulich
Anna Simon
Rachana Late
Bazgha Qutab
Ayush Kataria
Carolina Blanco
Kumar Ritwik
Emily Reynolds
Mahmood Majeed
Mahmood Majeed
Bazgha Qutab
Mahmood Majeed

ZS Compensation & Benefits Highlights

  • Healthcare Strength — Healthcare is described as a standout, with low‑cost medical through UMR/UnitedHealthcare, fully covered vision with an eyewear allowance, and mental‑health resources such as Talkspace, Bend Health, and a 24/7 EAP. Dental coverage is detailed as strong as well, including 100% for preventive/basic services and additional support for major and orthodontic care.
  • Parental & Family Support — The package includes 10 weeks of paid family leave and extensive family‑forming support (e.g., Carrot), plus backup childcare/eldercare/pet care and travel support like Milk Stork. These offerings indicate robust support for a wide range of family needs.
  • Leave & Time Off Breadth — Paid time off starts at 15 days from hire and increases to 20 days after 36 months, alongside 11 paid holidays, a floating holiday, and sick time with rollover. This structure signals broad time‑off provisions on paper.

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The Company
HQ: Evanston, IL
15,000 Employees
Year Founded: 1983

What We Do

ZS is a management consulting and technology firm that partners with companies to improve life and how we live it. We transform ideas into impact by bringing together data, science, technology and human ingenuity to deliver better outcomes for all. Founded in 1983, ZS has more than 15,000+ employees in over 40 offices worldwide.

Why Work With Us

ZS is home to passionate people who embrace innovative thinking, collaboration and a client-first mindset. Welcome to a company where new ideas are celebrated, curiosity is welcomed, learning opportunities are abundant and colleagues become lifelong connections.

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Hybrid Workspace

Employees engage in a combination of remote and on-site work.

The Flexible & Connected model is our ZS standard. ZSers decide where it makes the most sense for them to work each day given client or teamwork.

Typical time on-site: 3 days a week
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