A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech!
In Pharma Technical Development (PTD), we actively collaborate and develop creative technical solutions to efficiently transform scientific ideas into products. Our mission is to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, teamwork, dedication and mutual respect, and contributes every single day, continuously improving what it does.
Our global Analytical Development and Quality Control (ADQC) organization is a leader in developing, validating and executing physicochemical, immunochemical, and biological methods for our biologics pipeline. This function provides integrated analytical control strategies and systems that enable CMC development of biologic therapeutics, process development, product characterization, and drug delivery for biologic products from research (molecular assessment) through post product launch.
The OpportunityA Technical Development Principle Scientist position is available in the Analytical Development Department (within Pharma Technical Development organization). The selected candidate will participate as the analytical expert in a multi-disciplinary CMC (chemistry, manufacturing, and controls) team and will contribute to the development of several active clinical (phase 1-3) therapeutics simultaneously. The candidate will be responsible for designing and executing analytical studies that support process development and enable successful regulatory filings (IND, BLA). The successful candidate will have sound analytical chemistry fundamentals and an eagerness to flex between diverse analytical techniques including but not limited to high performance liquid chromatography, mass spectrometry, capillary electrophoresis, advanced spectroscopy.
Who you areRequired Qualifications
Ph.D. (4-6 additional years experience), M.S./B.S. (6-10 additional years experience) in Analytical Chemistry, Biology, Biochemistry, Chemistry, Chemical Engineering or related discipline
Sound fundamental knowledge in the analytical characterization of proteins or related therapeutic modalities
Well-rounded practical experience in the application of high performance liquid chromatography, liquid chromatography-mass spectrometry, capillary electrophoresis, and advanced spectroscopy with at least one area of deep analytical expertise
Knowledgeable about CMC (chemistry, manufacturing, control) development from Phase I to commercial
Self-motivated, have excellent organization, oral and written communication skills, and be willing to work both independently and as a team member. The candidate is expected to present data at internal and external meetings when appropriate.
Willing to work in a dynamic, fast-paced environment, and be capable of driving tasks to completion in a timely fashion.
Preferred Qualifications
Prior experience with small molecule linker drugs and antibody-drug conjugates (ADCs)
Prior experience supporting IND-enabling and BLA-enabling activities
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $120,800 - $224,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- Ph.D. in Analytical Chemistry, Biology or related discipline
- Sound analytical chemistry fundamentals
- Practical experience in high performance liquid chromatography and related techniques
- Knowledge of CMC development
- Excellent organization, oral and written communication skills
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.
