Sr. Scientist

Posted 2 Days Ago
Be an Early Applicant
South San Francisco, CA, USA
In-Office
150K-170K Annually
Senior level
Healthtech • Information Technology • Biotech
The Role
Lead development and clinical implementation of NGS-based MRD assays, designing and executing feasibility, optimization, and verification studies. Drive workflow automation, QC, throughput, and LIMS integration; author regulatory documentation and SOPs. Serve as SME for NGS, oncology genomics, and ctDNA technologies while collaborating cross-functionally and mentoring laboratory personnel to support technology transfer and commercialization.
Summary Generated by Built In

At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions. 

Our Values:

  • We Seek A Better Way: We pursue bold ideas, embrace complexity, and keep pushing forward.
  • We Make It Happen: We act with urgency, deliver with excellence, and always find a way. 
  • We Are Stronger Together: We engage with empathy, align around what's best for Veracyte, and celebrate as one team. 
  • We Care Deeply: We show up with integrity, kindness, and respect for one another. 

The Position:

We are seeking an experienced Senior Scientist to lead the development of next-generation MRD assays from concept through clinical lab implementation. This individual will drive technical strategy, experimental design, and scientific decision-making across assay development, automation, and workflow optimization. The ideal candidate has direct experience in NGS-based oncology diagnostics and a proven track record of developing clinical assays in regulated environments through cross-functional leadership and scientific innovation.

Responsibilities:
  • Lead the development, verification, and transfer of NGS-based MRD assays from concept through clinical lab implementation.
  • Independently develop workflows suitable for clinical operations, including automation, QC, throughput requirements, and LIMS integration.
  • Conceive innovative solutions and develop rigorous experimental strategies to advance assay performance, sensitivity, robustness, scalability, and operational readiness.
  • Design and execute feasibility, optimization, and verification studies, with independent ownership of objectives, study design, planning, execution, and analysis guided by systematic application of biochemistry and bioinformatic principles
  • Author and review protocols, SOPs, reports, requirements, risk assessments, and design control documentation supporting product development and regulatory compliance.
  • Serve as a subject matter expert in NGS, oncology genomics, and ctDNA/MRD technologies, leading troubleshooting and resolution of complex technical challenges.
  • Collaborate cross-functionally with Bioinformatics, Data Science, Operations, Clinical Laboratory, Automation, SW/LIMS, Quality, and Regulatory teams to develop and implement robust diagnostic products.
  • Support technology transfer, assay implementation, and commercialization activities, including training and mentoring laboratory personnel and junior scientists.
Who You Are:
  • NGS assay expert with deep theoretical and hands-on knowledge of the biochemistry underlying multi-component molecular biology methods at the sample preparation and assay level.  Has a track record of successfully troubleshooting and optimizing molecular biology techniques/assays in a developed workflow.
  • Bench scientist eager to participate directly in laboratory work independently and in cooperation/coordination with others. Must be able to mentor others and effectively manage (design, monitor, complete, troubleshoot) laboratory project tasks performed in the hands of others.
  • Rigorous and skilled in NGS data analysis, with command of common and assay-specific metrics and excellent data analysis and visualization skills using common statistical methods and software (JMP, R, Python)
  • Successful product developer with experience writing requirements and systematically building products under global PDP
  • Innovative technical leader eager to tackle complex scientific programs and generate solutions to challenging technical problems.
  • Team player who elevates performance within and across functions through technical collaboration, mentorship of junior scientists, and positive attitude
  • Practical developer with the ability to evaluate multiple technical variables and translate data into actionable decisions that consider program priorities, timelines, and cross-functional requirements
  • Clear and effective communicator with exceptional written and verbal communication skills
  • Flexible and open-minded contributor in the face of shifting resources & priorities
  • Passionate about developing diagnostics that improve outcomes for cancer patients.
Qualifications:
  • PhD in Molecular Biology, Genetics, Biochemistry, or a related field.
  • 6 – 7 years of post-doctoral and relevant industry experience focused on NGS wet-lab experimentation, preferably in a Product Development environment
  • Extensive experience developing NGS-based assays for clinical, diagnostic, or regulated applications, including the development of library preparation chemistries and direct experience with common clinical sample matrices (blood, tissue, FFPE)
  • Experience with automation and design and development of high-throughput workflows
  • Strong command of NGS-based genomic data analysis, interpretation, and visualization, including direct experience with common statistical methods and software (JMP, R, Python)
  • Strong background in cancer genomics, liquid biopsy, ctDNA, or related molecular diagnostic technologies. Direct experience developing MRD or liquid biopsy diagnostics a plus.
  • Experience with LDT product development under design control and quality system and regulatory requirements (CAP/CLIA, NYSDOH)
  • Proven ability to independently lead complex technical projects.

#LI-Onsite



The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to years of experience, skillset, geographic location, industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units.

Pay range
$150,000$170,000 USD

What We Can Offer You

Veracyte is a growing company that offers significant career opportunities if you are curious, driven, patient-oriented and aspire to help us build a great company. We offer competitive compensation and benefits, and are committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions. We are thrilled to be recognized as a 2024 Certified™ Great Place to Work® in both the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where passion meets purpose.


About Veracyte

Veracyte (Nasdaq: VCYT) is a global diagnostics company whose vision is to transform cancer care for patients all over the world. We empower clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our Veracyte Diagnostics Platform delivers high-performing cancer tests that are fueled by broad genomic and clinical data, deep bioinformatic and AI capabilities, and a powerful evidence-generation engine, which ultimately drives durable reimbursement and guideline inclusion for our tests, along with new insights to support continued innovation and pipeline development. For more information, please visit www.veracyte.com or follow us on LinkedIn or X (Twitter).

Veracyte, Inc. is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status. Veracyte participates in E-Verify in the United States. View our CCPA Disclosure Notice

If you receive any suspicious alerts or communications through LinkedIn or other online job sites for any position at Veracyte, please exercise caution and promptly report any concerns to [email protected]

Skills Required

  • PhD in Molecular Biology, Genetics, Biochemistry, or a related field.
  • 6-7 years of post-doctoral and relevant industry experience focused on NGS wet-lab experimentation, preferably in a product development environment.
  • Extensive experience developing NGS-based assays for clinical, diagnostic, or regulated applications, including library preparation chemistries and common clinical sample matrices (blood, tissue, FFPE).
  • Hands-on bench experience with ability to mentor junior scientists and manage laboratory project tasks.
  • Experience with automation and design and development of high-throughput workflows.
  • Strong command of NGS-based genomic data analysis, interpretation, and visualization, including experience with JMP, R, and Python.
  • Strong background in cancer genomics, liquid biopsy, and ctDNA technologies.
  • Experience with LDT product development under design control and quality system and regulatory requirements (CAP/CLIA, NYSDOH).
  • Experience authoring and reviewing protocols, SOPs, reports, requirements, risk assessments, and design control documentation supporting regulated product development.
  • Direct experience developing MRD or liquid biopsy diagnostics.
  • Proven ability to independently lead complex technical projects and drive technical strategy across cross-functional teams.

Veracyte Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Veracyte and has not been reviewed or approved by Veracyte.

  • Leave & Time Off Breadth Time away includes PTO, sick leave, paid medical leave, and paid parental leave; PTO is characterized as better than average with accrual increasing over tenure.
  • Retirement Support Retirement benefits include a 401(k) with employer match, with indications the match has been enhanced recently.
  • Equity Value & Accessibility Equity is accessible through an ESPP and RSUs for certain roles, and added share authorization signals continued equity availability.

Veracyte Insights

Am I A Good Fit?
beta
Get Personalized Job Insights.
Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.

The Company
HQ: South San Francisco, CA
596 Employees
Year Founded: 2008

What We Do

Veracyte is a global diagnostics company that empowers clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our growing menu of diagnostic tests answers important clinical questions to help patients avoid risky, costly procedures and interventions, and accelerate time to appropriate treatment

Similar Jobs

CrowdStrike Logo CrowdStrike

Senior Data Scientist

Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Remote or Hybrid
USA
11000 Employees
140K-215K Annually

Coursera + Udemy  Logo Coursera + Udemy

Senior Data Scientist

Artificial Intelligence • Consumer Web • Edtech • Enterprise Web • HR Tech • Social Impact • Generative AI
Remote or Hybrid
United States
1500 Employees
132K-166K Annually

Expedia Group Logo Expedia Group

Scientist

AdTech • eCommerce • Information Technology • Software • Travel • Generative AI
Hybrid
San Jose, CA, USA
16000 Employees
173K-299K Annually

Tempus AI Logo Tempus AI

Scientist

Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Remote or Hybrid
3 Locations
3775 Employees
125K-190K Annually

Similar Companies Hiring

OneImaging Thumbnail
Healthtech
Miami, FL
62 Employees
NODA AI Thumbnail
Artificial Intelligence • Information Technology • Software • Cybersecurity
Sydney, AU
54 Employees
Golden Pet Brands Thumbnail
Digital Media • eCommerce • Information Technology • Marketing Tech • Pet • Retail • Social Media
El Segundo, California
178 Employees

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account