Sr Manager, PLM Operations

Posted 2 Hours Ago
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Bengaluru, Bengaluru Urban, Karnataka, IND
In-Office
Senior level
Healthtech • Biotech
The Role
Leads PLM strategy and operations in India, owning the capability roadmap, governance, transformation priorities, operating models, and execution discipline. Manages strategy and operations teams while partnering with R&D, supply chain, quality, manufacturing, IT, MDM, and architecture stakeholders. Drives data quality, configuration governance, process improvement, automation, analytics, AI adoption, value realization, executive alignment, and talent development across the PLM function.
Summary Generated by Built In
What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Position Summary:

The Senior Manager - PLM Strategy & Operations is responsible for leading Illumina’s Product Lifecycle Management strategy and operations in India, with accountability for advancing the PLM capability roadmap, strengthening enterprise change governance, and enabling scalable product lifecycle execution across business functions. This role leads a small PLM strategy team and a larger PLM operations team, connecting long-term business priorities with practical operating models, process transformation, data readiness, and disciplined execution.

The position partners closely with R&D, Supply Chain, Quality, Manufacturing, IT, MDM, Solution Architecture, Data Architecture, and other enterprise stakeholders to translate business needs into PLM strategy, transformation priorities, and measurable outcomes. The role is expected to operate with strong strategic problem-solving, executive-level influence, cross-functional alignment, and the ability to define the future state for PLM capabilities while ensuring operational excellence in day-to-day delivery.

Changes to individual responsibilities may occur due to business needs, and other related duties may be assigned.

Scope of Responsibilities:

  • Own and evolve the PLM strategy and multi-year roadmap for the India organization, aligned with enterprise objectives, product lifecycle priorities, operational needs, and digital transformation goals.
  • Lead both PLM strategy and operations teams, including a small senior strategy team and a larger operations organization, while building capability, accountability, and execution discipline across the function.
  • Define future-state PLM capabilities, operating models, governance mechanisms, and process improvement priorities that enable scalable, compliant, and efficient product lifecycle management.
  • Partner with cross-functional leaders across R&D, Supply Chain, Quality, Manufacturing, IT, MDM, Solution Architecture, and Data Architecture to align business intent, change impact, data readiness, implementation priorities, and adoption outcomes.
  • Lead complex problem solving across ambiguous business, process, data, and technology challenges where solutions require enterprise thinking, prioritization, stakeholder alignment, and structured decision-making.
  • Drive transformation initiatives that simplify change management, improve data quality, strengthen configuration governance, reduce process friction, and increase business value from PLM platforms and related enterprise systems.
  • Establish portfolio and governance frameworks to prioritize PLM initiatives, manage risk, sequence investments, and ensure clear linkage between roadmap priorities, measurable outcomes, and enterprise value realization.
  • Influence senior stakeholders and cross-functional partners through strategic recommendations, business cases, trade-off analysis, and clear communication of risks, dependencies, and decision points.
  • Champion responsible adoption of digital capabilities, automation, analytics, AI/LLM opportunities, and process mining to improve PLM effectiveness, operational productivity, user experience, and decision support.
  • Ensure day-to-day PLM operations remain effective, compliant, and service-oriented while progressively shifting the organization from transactional execution to strategic capability ownership.
  • Develop talent, mentoring senior professionals and people leaders, strengthening succession depth, and building a high-performing organization capable of supporting both current operations and future-state transformation.
  • Represent the PLM function in enterprise forums, audits, transformation reviews, and leadership discussions, ensuring the function is viewed as a strategic business partner and not only an operational support team.

Required Experience and Capabilities:

  • Demonstrated ability to define strategy, build roadmaps, solve complex enterprise problems, and translate business priorities into actionable transformation plans.
  • Strong understanding of PLM processes, change management, item and BoM lifecycle, configuration management, data governance, and cross-functional product lifecycle execution.
  • Experience leading managers, senior professionals, and large operational teams while also guiding strategy, transformation, and capability-building initiatives.
  • Proven ability to influence senior leaders and cross-functional stakeholders in complex, matrixed environments without relying solely on positional authority.
  • Experience developing governance models, business cases, KPI frameworks, value realization measures, and operating rhythms that connect strategy to execution.
  • Working knowledge of PLM platforms, ERP interactions, MDM concepts, solution architecture, data architecture, automation, analytics, and emerging digital capabilities preferred.
  • Ability to balance near-term operational performance with longer-term capability building, organizational maturity, and future-state design.

Experience/Education:

  • Typically requires a Bachelor’s degree in Engineering, Life Sciences, Information Systems, Business, Operations, or a related discipline, with a minimum of 12 years of progressive experience in PLM, operations leadership, enterprise transformation, product lifecycle management, business process architecture, MDM, digital strategy, or related functional environments.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Skills Required

  • Bachelor’s degree in Engineering, Life Sciences, Information Systems, Business, Operations, or a related discipline
  • Minimum 12 years of progressive experience in PLM, operations leadership, enterprise transformation, product lifecycle management, business process architecture, MDM, digital strategy, or related environments
  • Experience defining strategy, building roadmaps, solving complex enterprise problems, and creating actionable transformation plans
  • Strong understanding of PLM processes, change management, item and bill of materials lifecycle, configuration management, data governance, and cross-functional product lifecycle execution
  • Experience leading managers, senior professionals, and large operational teams
  • Ability to influence senior leaders and cross-functional stakeholders in complex, matrixed environments
  • Experience developing governance models, business cases, KPI frameworks, value realization measures, and operating rhythms
  • Working knowledge of PLM platforms, ERP interactions, MDM concepts, solution architecture, data architecture, automation, analytics, and emerging digital capabilities
  • Ability to balance near-term operational performance with long-term capability building and future-state design

Illumina Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Illumina and has not been reviewed or approved by Illumina.

  • Healthcare Strength — Health coverage includes comprehensive medical (HMO/PPO), dental, vision, mental health, life, and disability insurance with options such as FSAs/HSAs and wellness resources. Offerings are described as robust across regions with customization in certain locations.
  • Leave & Time Off Breadth — Time-off programs include flexible schedules and remote work, PTO or flexible time off, paid holidays and sick leave, and volunteer time. Company-wide shutdowns during summer and winter add additional paid time away.
  • Parental & Family Support — Family-focused programs include fertility assistance, adoption assistance, and reproductive health support alongside family medical leave. Paid parental leave is provided, with specifics varying by country and employment status.

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The Company
HQ: San Diego, CA
7,400 Employees
Year Founded: 1998

What We Do

Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.

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