About Grafton Sciences
We’re building AI systems with general physical ability — the capacity to experiment, engineer, or manufacture anything. We believe achieving this is a key step towards building superintelligence. With deep technical roots and real-world progress at scale (e.g., a $42M NIH project), we’re pushing the frontier of physical AI. Joining us means inventing from first principles, owning real systems end-to-end, and helping build a capability the world has never had before.
About the Role
We’re seeking a Senior Systems Integration Engineer to unify complex mechanical, electrical, firmware, controls, and robotics subsystems into fully operational tools and automated cells. You’ll own bring-up, debugging, hardware–software interactions, and system-level reliability. This is a deeply hands-on role for someone who thrives on making the whole system work — diagnosing cross-discipline issues, validating performance, and driving integration from prototype to stable operation.
Responsibilities
• Integrate mechanical, electrical, controls, firmware, and robotics components into reliable end-to-end systems.
• Lead system bring-up, debugging, calibration, and validation across complex electromechanical assemblies.
• Diagnose cross-discipline failures, trace root causes, and drive rapid fixes involving multiple engineering teams.
• Collaborate across robotics, automation, electrical, mechanical, and software teams to ensure smooth system-level operation.
Qualifications
• Strong experience integrating hardware and software systems in robotics, automation, manufacturing, or complex electromechanical products.
• Deep debugging instincts across mechanical, electrical, firmware, and controls interfaces.
• Ability to reason about system-level behavior, identify failure modes, and drive reliable operation across subsystems.
• Comfortable working hands-on with equipment, instrumentation, and prototypes in fast-moving engineering environments.
Above all, we look for candidates who can demonstrate world-class excellence.
Compensation
We offer competitive salary, meaningful equity, and benefits.
Top Skills
What We Do
Grafton Sciences (formerly, Grafton Biosciences) is pioneering physical general intelligence, autonomous systems that merge artificial intelligence, robotics, and reasoning to accelerate scientific discovery.
By designing platforms for autonomous discovery, we aim to solve the grandest challenges across science. As part of our ongoing initiatives in disease, we have received a $42.5 million contract from ARPA-H to solve early detection of cancer at Stage 1.
Backed by visionary partners, we are redefining how discovery itself is done.
