At MetrumRG, we’re a diverse, mission-driven team working to transform biomedical decision-making and improve global health. We’re passionate about continuous learning and committed to openly sharing knowledge with the scientific community.
We’re looking for a PK/PD Modeling and Simulation Scientist with a minimum of 5 years of post-doctoral experience to join our collaborative, fast-moving environment. We know our success depends on the well-being and fulfillment of our team, so we strive to make work engaging, rewarding, and fun.
In this role, you’ll contribute to biomedical research, development, and post-marketing efforts across drugs, biologics, devices, and diagnostics. You’ll design and apply quantitative pharmacometric strategies to guide decision-making and accelerate innovation. You’ll also take part in reporting, publications, and ongoing professional development in modeling and simulation.
If you’re energized by scientific growth, meaningful work, and collaboration—we’d love to hear from you.
- Lead interactions with biomedical industry collaborators
- Develop strategies and conduct modeling and simulation to support biomedical decision making
- Develop population pharmacokinetic (PK), pharmacodynamic (PD), exposure-response, disease progression, and/or systems pharmacology models
- Apply models to support decision-making through Monte-Carlo simulation
- Perform model-based meta-analysis of therapeutic area summary-level data
- Perform quality control of modeling and simulation analyses
- Prepare technical reports, manuscripts, and presentations
- Work collaboratively within assigned agile project team(s) to accomplish team goals
- Required: Strong proficiency with a scriptable modeling and simulation language (e.g. R, MatLab, Python)
- Required: Advanced expertise with domain-specific modeling software (e.g. NONMEM, ADAPT, Monolix) and Bayesian modeling software (e.g. Stan, JAGS, OpenBUGS)
- Desirable: Experience with Shiny, Markdown, LaTeX, unix/Linux, subversion, git
- Desirable: A strong understanding of statistical analysis of longitudinal, landmark, and repeated-measures, continuous or categorical data, within a multi-level hierarchy
- Required: M.S. or Ph.D. Degree in Mathematics, Statistics, Pharmacometrics, Pharmacokinetics, Bioinformatics, Chemical or Biomedical Engineering, or related quantitative field
- Required: Minimum five years of experience in PKPD modeling and simulation post-graduate degree
The job frequently requires working at a computer terminal, standing or sitting, and the ability to operate a computer with proficiency.
Work Environment:The work environment is quiet with no adverse conditions.
Metrum Research Group offers competitive salaries and an excellent benefits package. You can read more about us by clicking the link at the top of this page, 'Company Website'.
Metrum Research Group EEO Statement
MetrumRG believes that innovation is cultivated when we challenge each other with new ideas and perspectives. MetrumRG is an equal opportunity employer that is committed to building a diverse and inclusive team. All employment decisions are based on qualifications, merit, and business needs, and we prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, gender identity, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
MetrumRG is committed to providing equal employment opportunities and reasonable accommodations for candidates and employees with disabilities. We encourage all qualified candidates to apply for positions within our organization. If you require reasonable accommodation because of a medical condition for the application or interview process, please contact Scotti Rylands or our Talent and Culture Department, (860)735-7043 x-622, or message us and we will work with you to meet your needs.
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What We Do
Metrum Research Group, established in 2004, is a global leader in biomedical modeling and simulation. We have enabled rational and strategic decision making for more than 200 companies on over 700 projects. At Metrum Research Group we support our clients in advancing drug development programs by supplying them with the highest quality scientific expertise. For more information about Metrum Research Group please visit metrumrg.com
