The Role
WHO WE ARE
Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Senior Scientist, Discovery Immunology to work onsite based in our South San Francisco office.
ArsenalBio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.
Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.
This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.
WHAT YOU’LL DO
- Design, develop, and execute a broad range of cell-based functional and phenotypic in vitro assays to identify mechanisms of T cell activity under a variety of environments
- Work in teams as the immunology SME to drive the development, execution and interpretation of manual and automated CRISPR screens to identify novel ways to enhance and probe T cells
- Drive scientific and technical innovation collaboratively with other members of ArsenalBio
- Summarize and synthesize data across experiments and present findings at all levels of the organization
- Provide exceptional scientific leadership and mentorship to scientists and research associates
- Work collaboratively and proactively with colleagues in automation, computational biology, NGS and discovery in a matrixed team structure
WHO YOU ARE
- PhD in Immunology, Cellular Biology, Cancer Biology, or a related field with 2+ years of experience, OR a Master’s degree with 5+ years of experience, OR a Bachelor’s degree with 7+ years of experience. Industry experience is preferred but not required
- Strong background in immunology with a focus on T cell biology and direct experience with primary immune cell culture; prior experience with genetic engineering of primary immune cells and knowledge of tumor immunology and/or autoimmunity preferred
- Expertise in successfully developing and executing in vitro cellular assays including immune cell phenotyping, functional assessments, proliferation and cytokine analysis
- Outstanding written and oral communication skills and the ability to organize and communicate complex data sets clearly and concisely to key stakeholders from diverse backgrounds
- Ability to thrive in a fast-paced, collaborative team environment, effectively managing multiple priorities with a proactive mindset, strong self-motivation, and exceptional organizational skills.
- Experience with general molecular biology techniques would be preferred
- Previous experience with pooled/arrayed screening and interpreting scRNAseq and/or screening data would be preferred
- Experience with tumor or autoimmune disease models would be preferred
Preferred Qualifications:
BENEFITS AND PAY
ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge.
Our people-first culture cultivates a deep respect for humanity, not only in those we serve but also in one another. We take pride in being part of a company that values and celebrates diversity—in experiences, ideas, and interests. We are empowered in an environment that embraces unity and inclusivity, fostering a sense of belonging and mutual respect.
We provide powerful tools to empower our employees to take charge of their career paths and reach their full potential. At ArsenalBio, we believe in investing in our employees' well-being—both professionally and personally—because our people are our most valuable asset. Our essential team members bring exceptional expertise in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software, and other fields to turn the possibilities of tomorrow into the realities of today.
We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.
We are an equal opportunity employer and deeply value diversity within our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.
The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $131,200- $160,700. Salary ranges for other locations may vary. Base pay offered may vary based on job-related knowledge, experience, education, and location. Beyond these considerations, we are committed to pay equity and consider the internal equity of our current employees when making any final offers.
To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias or to ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.
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The Company
What We Do
ArsenalBio is a privately held, programmable cell therapy company focused on the realization of solid tumor cell therapy to defeat cancer. Our discovery engine comprises precise CRISPR-enabled genome editing, integrated circuits incorporating logic gates for improved tumor targeting, and therapeutic enhancements enabling multiple pharmaceutical functions. With our programmable and computationally driven approach, we aim for enhanced and broader efficacy, increased patient safety, reduced provider costs and expanded market access. Our team is engineering living medicines to attack cancer’s inherent multi-faceted nature and bring dramatic improvements to the lives of patients.
