Senior Scientist, Analytical Development

Posted 3 Days Ago
Be an Early Applicant
Boston, MA, USA
Hybrid
145K-165K Annually
Senior level
Artificial Intelligence • Machine Learning • Biotech • Design
A culture of recombination
The Role
Lead analytical development for antibodies, multispecifics, Fc-fusions, proteins, and cell and gene therapy therapeutics. Design experiments, develop and optimize HPLC/UPLC, mass spectrometry, capillary electrophoresis, and related characterization methods, and communicate findings across cross-functional teams. Mentor junior scientists, address complex analytical challenges, improve workflow throughput and reproducibility, and support transparent, data-driven project decisions.
Summary Generated by Built In

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.

We are seeking a Senior Scientist to join our Analytical Sciences team. In this role, you will lead analytical efforts to develop and optimize methods supporting the characterization of antibodies and diverse antibody formats (including bispecifics and other multispecifics, Fc-fusions, and other engineered architectures), proteins, and CGT therapeutics. You will actively collaborate with multiple teams, ensuring that your work and insights are aligned with broader program goals. You will apply your technical skills to address complex analytical challenges, continuously grow your expertise, and contribute to a culture of scientific rigor.

About the Role:

  • Lead analytical development efforts for key projects, designing and implementing experiments to generate actionable results.

  • Engage with cross-functional teams to share findings, raise critical analytical issues, and support aligned decision-making.

  • Manage and mentor junior scientists, focusing on experimental design, problem-solving, and fostering a culture of scientific rigor.

  • Ensure transparency and maintain consistent communication with project stakeholders about progress, risks, and results.

  • Continuously develop and apply technical skills in analytical method development (HPLC/UPLC, MS, CE, and other protein characterization techniques) to address evolving project needs.

  • Identify opportunities to improve workflows, analytical throughput, and reproducibility.

About You:

  • Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 4+ years of relevant biopharma analytical experience, or M.S. with 7+ years of relevant experience.

  • Hands-on experience in analytical method development (HPLC/UPLC, MS, CE, UV, etc.) across diverse antibody formats, with a willingness and aptitude to rapidly expand technical expertise.

  • Strong understanding of antibody structural formats and how format-specific architecture (bispecifics/multispecifics, Fc-fusions, biosimilars, and other engineered constructs) shapes analytical strategy and method selection.

  • Strong collaboration and alignment skills, with the ability to communicate findings clearly and maintain transparency with stakeholders.

  • Experience mentoring junior scientists, guiding them in experimental design and problem-solving, and fostering a culture of rigorous science.

  • Proactive problem-solving mindset, with the ability to apply analytical skills to address complex project challenges.

  • Experience engaging across teams and functions, influencing decisions through effective data-driven communication.

  • Excellent written and verbal communication skills.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Skills Required

  • Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or a related field plus 4 or more years of relevant biopharma analytical experience
  • Alternatively, M.S. degree plus 7 or more years of relevant experience
  • Hands-on analytical method development experience using HPLC, UPLC, mass spectrometry, capillary electrophoresis, and UV techniques
  • Experience working across diverse antibody formats, including bispecifics, multispecifics, Fc-fusions, biosimilars, and engineered constructs
  • Strong understanding of antibody structural formats and their impact on analytical strategy and method selection
  • Experience mentoring junior scientists and guiding experimental design and problem-solving
  • Strong cross-functional collaboration, stakeholder communication, and data-driven decision-making skills
  • Excellent written and verbal communication skills

Asimov Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Asimov and has not been reviewed or approved by Asimov.

  • Healthcare Strength — Medical, dental, and vision coverage is positioned as comprehensive, with additional protection benefits like life and disability insurance and access to an FSA. Medical coverage is also described as fully covered in at least one case, reinforcing perceived strength in baseline health benefits.
  • Retirement Support — A 401(k) plan with a company match is included as a core benefit and is repeatedly listed as part of the standard package. This adds a stable long-term savings component alongside other elements of total compensation.
  • Leave & Time Off Breadth — Paid holidays and sick time are complemented by an unlimited vacation policy and flexible scheduling. This combination suggests broad time-off coverage, while day-to-day usability can vary with workload and team norms.

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The Company
HQ: Cambridge, MA
95 Employees
Year Founded: 2017

What We Do

Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

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